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In Schiebinger et al. (2017), the authors use optimal transport of measures on empirical distributions arising from biological experiments to relate the single cell RNA sequencing profiles for induced pluripotent stem cells differentiating.…

Quantitative Methods · Quantitative Biology 2017-10-23 Salil Bhate

The goal of Feature Selection - comprising filter, wrapper, and embedded approaches - is to find the optimal feature subset for designated downstream tasks. Nevertheless, current feature selection methods are limited by: 1) the selection…

Machine Learning · Computer Science 2023-09-18 Meng Xiao , Dongjie Wang , Min Wu , Pengfei Wang , Yuanchun Zhou , Yanjie Fu

We investigate the robustness of Large Language Models (LLMs) to structural interventions by deleting and swapping adjacent layers during inference. Surprisingly, models retain 72-95% of their original top-1 prediction accuracy without any…

Machine Learning · Computer Science 2025-06-17 Vedang Lad , Jin Hwa Lee , Wes Gurnee , Max Tegmark

Despite the empirical success of foundation models, we do not have a systematic characterization of the representations that these models learn. In this paper, we establish the contexture theory. It shows that a large class of…

Machine Learning · Computer Science 2025-05-06 Runtian Zhai , Kai Yang , Che-Ping Tsai , Burak Varici , Zico Kolter , Pradeep Ravikumar

Diffusion Transformers have achieved state-of-the-art performance in class-conditional and multimodal generation, yet the structure of their learned conditional embeddings remains poorly understood. In this work, we present the first…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Trung X. Pham , Kang Zhang , Ji Woo Hong , Chang D. Yoo

The proposed method extends upon the representational output of semantic instance segmentation by explicitly including both visible and occluded parts. A fully convolutional network is trained to produce consistent pixel-level embedding…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Yanfeng Liu , Eric Psota , Lance Pérez

Contextual embeddings derived from transformer-based neural language models have shown state-of-the-art performance for various tasks such as question answering, sentiment analysis, and textual similarity in recent years. Extensive work…

Computation and Language · Computer Science 2020-11-03 Brihi Joshi , Neil Shah , Francesco Barbieri , Leonardo Neves

Predicting the response of a patient to a cancer treatment is of high interest. Nonetheless, this task is still challenging from a medical point of view due to the complexity of the interaction between the patient organism and the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Mahfoud Chaibi , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

Understanding which inductive biases could be helpful for the unsupervised learning of object-centric representations of natural scenes is challenging. In this paper, we systematically investigate the performance of two models on datasets…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Samuele Papa , Ole Winther , Andrea Dittadi

We propose TabTransformer, a novel deep tabular data modeling architecture for supervised and semi-supervised learning. The TabTransformer is built upon self-attention based Transformers. The Transformer layers transform the embeddings of…

Machine Learning · Computer Science 2020-12-15 Xin Huang , Ashish Khetan , Milan Cvitkovic , Zohar Karnin

Coordinated cellular movements are key processes in tissue morphogenesis. Using a cell-based modeling approach we study the dynamics of epithelial layers lining surfaces with constant and varying curvature. We demonstrate that extrinsic…

Soft Condensed Matter · Physics 2024-03-21 Lea Happel , Axel Voigt

Conventional deep networks rely on one-way backpropagation that overlooks reconciling high-level predictions with lower-level representations. We propose \emph{Contextual Feedback Loops} (CFLs), a lightweight mechanism that re-injects…

Machine Learning · Computer Science 2025-04-30 Jacob Fein-Ashley , Rajgopal Kannan , Viktor Prasanna

Epithelial cell layers on soft elastic substrates or pillar arrays are commonly used as model systems for investigating the role of force in tissue growth, maintenance and repair. Here we show analytically that the experimentally observed…

Tissues and Organs · Quantitative Biology 2012-01-16 Carina M. Edwards , Ulrich S. Schwarz

We consider the problem of accurately identifying cell boundaries and labeling individual cells in confocal microscopy images, specifically, 3D image stacks of cells with tagged cell membranes. Precise identification of cell boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Jiaxiang Jiang , Po-Yu Kao , Samuel A. Belteton , Daniel B. Szymanski , B. S. Manjunath

Masked Image Modeling (MIM) achieves outstanding success in self-supervised representation learning. Unfortunately, MIM models typically have huge computational burden and slow learning process, which is an inevitable obstacle for their…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Haoqing Wang , Yehui Tang , Yunhe Wang , Jianyuan Guo , Zhi-Hong Deng , Kai Han

Deploying foundation models in embodied edge systems is fundamentally a systems problem, not just a problem of model compression. Real-time control must operate within strict size, weight, and power constraints, where memory traffic,…

Recent studies show that deep vision-only and language-only models--trained on disjoint modalities--nonetheless project their inputs into a partially aligned representational space. Yet we still lack a clear picture of where in each network…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Zoe Wanying He , Sean Trott , Meenakshi Khosla

Inferencing with network data necessitates the mapping of its nodes into a vector space, where the relationships are preserved. However, with multi-layered networks, where multiple types of relationships exist for the same set of nodes, it…

Social and Information Networks · Computer Science 2019-03-05 Huan Song , Jayaraman J. Thiagarajan

A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…

Biological Physics · Physics 2015-05-30 Makiko Nonomura

Autoregressive language models have demonstrated a remarkable ability to extract latent structure from text. The embeddings from large language models have been shown to capture aspects of the syntax and semantics of language. But what…

Machine Learning · Computer Science 2026-01-09 Liyi Zhang , Michael Y. Li , R. Thomas McCoy , Theodore R. Sumers , Jian-Qiao Zhu , Thomas L. Griffiths
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