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Synthetic data generation in histopathology faces unique challenges: preserving tissue heterogeneity, capturing subtle morphological features, and scaling to unannotated datasets. We present a latent diffusion model that generates realistic…
CNNs have been widely applied for medical image analysis. However, limited memory capacity is one of the most common drawbacks of processing high-resolution 3D volumetric data. 3D volumes are usually cropped or downsized first before…
This paper introduces a network for volumetric segmentation that learns from sparsely annotated volumetric images. We outline two attractive use cases of this method: (1) In a semi-automated setup, the user annotates some slices in the…
Scaling up model size and training data has advanced foundation models for instance-level perception, achieving state-of-the-art in-domain and zero-shot performance across object detection and segmentation. However, their high computational…
Understanding the kinetics of drug-protein interactions is paramount for drug design, yet the field lacks large-scale, dynamic data to move beyond static structural analysis. Here, we present DD-03B, a massively scalable database providing…
The mature soybean plants are of complex architecture with pods frequently touching each other, posing a challenge for in-situ segmentation of on-branch soybean pods. Deep learning-based methods can achieve accurate training and strong…
Falls represent a significant cause of injury among the elderly population. Extensive research has been devoted to the utilization of wearable IMU sensors in conjunction with machine learning techniques for fall detection. To address the…
Data-driven methods such as convolutional neural networks (CNNs) are known to deliver state-of-the-art performance on image recognition tasks when the training data are abundant. However, in some instances, such as change detection in…
A key limitation of deep convolutional neural networks (DCNN) based image segmentation methods is the lack of generalizability. Manually traced training images are typically required when segmenting organs in a new imaging modality or from…
Generalist biomedical image segmentation models such as Cellpose are increasingly applied across diverse imaging modalities and cell types. However, two critical challenges remain underexplored: (1) the extent of training data redundancy…
Existing 3D instance segmentation methods are predominated by the bottom-up design -- manually fine-tuned algorithm to group points into clusters followed by a refinement network. However, by relying on the quality of the clusters, these…
The performance of deep neural networks is strongly influenced by the quality of their training data. However, mitigating dataset bias by manually curating challenging edge cases remains a major bottleneck. To address this, we propose an…
The use of machine learning (ML) methods for development of robust and flexible visual inspection system has shown promising. However their performance is highly dependent on the amount and diversity of training data. This is often…
Foundation models for interactive segmentation in 2D natural images and videos have sparked significant interest in building 3D foundation models for medical imaging. However, the domain gaps and clinical use cases for 3D medical imaging…
We introduce EvObj for unsupervised 3D instance segmentation that bridges the geometric domain gap between synthetic pretraining data and real-world point clouds. Current methods suffer from structural discrepancies when transferring object…
Pseudo-healthy synthesis is the task of creating a subject-specific `healthy' image from a pathological one. Such images can be helpful in tasks such as anomaly detection and understanding changes induced by pathology and disease. In this…
Surgical planning and training based on machine learning requires a large amount of 3D anatomical models reconstructed from medical imaging, which is currently one of the major bottlenecks. Obtaining these data from real patients and during…
Increasing data set sizes of 3D microscopy imaging experiments demand for an automation of segmentation processes to be able to extract meaningful biomedical information. Due to the shortage of annotated 3D image data that can be used for…
Nuclei segmentation and classification is a significant process in pathology image analysis. Deep learning-based approaches have greatly contributed to the higher accuracy of this task. However, those approaches suffer from the imbalanced…
Segmentation of structural parts of 3D models of plants is an important step for plant phenotyping, especially for monitoring architectural and morphological traits. Current state-of-the art approaches rely on hand-crafted 3D local features…