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Deep learning based techniques have been recently used with promising results for data integration problems. Some methods directly use pre-trained embeddings that were trained on a large corpus such as Wikipedia. However, they may not…

Databases · Computer Science 2020-09-04 Riccardo Cappuzzo , Paolo Papotti , Saravanan Thirumuruganathan

We present BEEP (Biomedical Evidence-Enhanced Predictions), a novel approach for clinical outcome prediction that retrieves patient-specific medical literature and incorporates it into predictive models. Based on each individual patient's…

Computation and Language · Computer Science 2022-11-17 Aakanksha Naik , Sravanthi Parasa , Sergey Feldman , Lucy Lu Wang , Tom Hope

Epilepsy is a chronic neurological disorder with a significant prevalence. However, there is still no adequate technological support to enable epilepsy detection and continuous outpatient monitoring in everyday life. Hyperdimensional (HD)…

Neural and Evolutionary Computing · Computer Science 2024-04-30 Una Pale , Tomas Teijeiro , David Atienza

The recent advancement of large language models has spurred a growing trend of integrating pre-trained language model (PLM) embeddings into topic models, fundamentally reshaping how topics capture semantic structure. Classical models such…

Computation and Language · Computer Science 2026-03-12 Hanlin Xiao , Mauricio A. Álvarez , Rainer Breitling

Retrieval augmentation has become an effective solution to empower large language models (LLMs) with external and verified knowledge sources from the database, which overcomes the limitations and hallucinations of LLMs in handling…

Information Retrieval · Computer Science 2023-11-21 Tong Wu , Yulei Qin , Enwei Zhang , Zihan Xu , Yuting Gao , Ke Li , Xing Sun

Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

Computation and Language · Computer Science 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Pre-trained language models (PTLMs) acquire domain-independent linguistic knowledge through pre-training with massive textual resources. Additional pre-training is effective in adapting PTLMs to domains that are not well covered by the…

Computation and Language · Computer Science 2021-09-20 Kosuke Nishida , Kyosuke Nishida , Sen Yoshida

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

Computation and Language · Computer Science 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

Post-stroke patient rehabilitation requires precise, personalized treatment plans. Natural Language Processing (NLP) offers potential to extract valuable exercise information from clinical notes, aiding in the development of more effective…

Computation and Language · Computer Science 2024-03-18 Sonish Sivarajkumar , Fengyi Gao , Parker E. Denny , Bayan M. Aldhahwani , Shyam Visweswaran , Allyn Bove , Yanshan Wang

Deep learning models have demonstrated superior performance in various healthcare applications. However, the major limitation of these deep models is usually the lack of high-quality training data due to the private and sensitive nature of…

Computation and Language · Computer Science 2022-11-15 Qiuhao Lu , Dejing Dou , Thien Huu Nguyen

Large Language Models (LLMs) have shown promise in clinical applications through prompt engineering, allowing flexible clinical predictions. However, they struggle to produce reliable prediction probabilities, which are crucial for…

Artificial Intelligence · Computer Science 2024-12-05 Bowen Gu , Rishi J. Desai , Kueiyu Joshua Lin , Jie Yang

Objective: To evaluate large language models (LLMs) against supervised baselines for fine-grained, lesion-level detection of incidentalomas requiring follow-up, addressing the limitations of current document-level classification systems.…

Computation and Language · Computer Science 2025-12-08 Namu Park , Farzad Ahmed , Zhaoyi Sun , Kevin Lybarger , Ethan Breinhorst , Julie Hu , Ozlem Uzuner , Martin Gunn , Meliha Yetisgen

The widespread adoption of large language models (LLMs) makes it important to recognize their strengths and limitations. We argue that in order to develop a holistic understanding of these systems we need to consider the problem that they…

Computation and Language · Computer Science 2023-09-26 R. Thomas McCoy , Shunyu Yao , Dan Friedman , Matthew Hardy , Thomas L. Griffiths

Estimating the impact of trauma treatment protocols is complicated by the high dimensional yet finite sample nature of trauma data collected from observational studies. Viscoelastic assays are highly predictive measures of hemostasis.…

Applications · Statistics 2022-09-27 Linqing Wei , Lucy Z. Kornblith , Alan Hubbard

Large-scale EHR prediction across institutions is hindered by substantial heterogeneity in schemas and code systems. Although Common Data Models (CDMs) can standardize records for multi-institutional learning, the manual harmonization and…

Computation and Language · Computer Science 2026-04-02 Kyunghoon Hur , Heeyoung Kwak , Jinsu Jang , Nakhwan Kim , Edward Choi

Causal structure discovery from observations can be improved by integrating background knowledge provided by an expert to reduce the hypothesis space. Recently, Large Language Models (LLMs) have begun to be considered as sources of prior…

Machine Learning · Computer Science 2024-05-24 Victor-Alexandru Darvariu , Stephen Hailes , Mirco Musolesi

Large language models (LLMs) trained with next-word-prediction have achieved success as clinical foundation models. Representations from these language backbones yield strong linear probe performance across biomedical tasks, suggesting that…

Artificial Intelligence · Computer Science 2026-01-30 Irsyad Adam , Zekai Chen , David Laprade , Shaun Porwal , David Laub , Erik Reinertsen , Arda Pekis , Kevin Brown

Chemotherapy for cancer treatment is costly and accompanied by severe side effects, highlighting the critical need for early prediction of treatment outcomes to improve patient management and informed decision-making. Predictive models for…

Recent years have witnessed increasing interests in prompt-based learning in which models can be trained on only a few annotated instances, making them suitable in low-resource settings. When using prompt-based learning for text…

Computation and Language · Computer Science 2023-05-11 Hongjing Li , Hanqi Yan , Yanran Li , Li Qian , Yulan He , Lin Gui