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Surface Enhanced Raman Spectroscopy (SERS) is a well-established technique for enhancing Raman signals. Recently photonic integrated circuits have been used, as an alternative to microscopy based excitation and collection, to probe SERS…

Surface-Enhanced Raman Scattering (SERS) allows for detection and identification of molecular vibrational fingerprints in minute sample quantities. The SERS process can be also exploited for optical manipulation of molecular vibrations. We…

The long-range action of surface-enhanced Raman scattering (SERS) is probed via distance-dependent measurements of molecular Raman spectra. To this end, identical SERS substrates composed of irregular silver nanoisland arrays were covered…

Materials Science · Physics 2015-06-12 V. I. Kukushkin , A. B. Van'kov , I. V. Kukushkin

Raman spectroscopy, a photonic modality based on the inelastic backscattering of coherent light, is a valuable asset to the intraoperative sensing space, offering non-ionizing potential and highly-specific molecular fingerprint-like…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Ashutosh Raman , Ren A. Odion , Kent K. Yamamoto , Weston Ross , Tuan Vo-Dinh , Patrick J. Codd

Surface-enhanced Raman spectroscopy (SERS) allows single-molecule detection due to the strong field localization occurring at sharp bends or kinks of the metal-vacuum interface. An important question concerns the limits of the signal…

Optics · Physics 2008-06-19 Sanshui Xiao , Niels Asger Mortensen , Antti-Pekka Jauho

Dynamic surface-enhanced Raman spectroscopy (SERS) is nowadays one of the most interesting applications of SERS, in particular for single molecule studies. In fact, it enables the study of real-time processes at the molecular level. This…

We propose an integrated surface enhanced Raman scattering (SERS) chip based on liquid-core waveguide with total reflection, through which the depression of leaky mode enable a long propagating distance. An Raman enhancement factor for…

Optics · Physics 2015-12-08 Chunhong Lai , Gang Chen , Li Chen , Junhui Li , Qinghao Liu , Yi Xu

The ability to perform sensitive, real-time, in situ, multiplex chemical analysis is indispensable for diverse applications such as human health monitoring, food safety testing, forensic analysis, environmental sensing, and homeland…

Surface-enhanced Raman scattering (SERS) is a critical tool for chemical sensing and spectroscopy, and a key question is how to optimally design nanostructures for maximizing SERS. We present fundamental limits on spatially-averaged SERS…

Optics · Physics 2025-02-17 Pengning Chao , Ian M. Hammond , Steven G. Johnson

Single-molecule detection with chemical specificity is a powerful and much desired tool for biology, chemistry, physics, and sensing technologies. Surface-enhanced spectroscopies enable single molecule studies, yet reliable substrates of…

Mesoscale and Nanoscale Physics · Physics 2008-02-22 D. R. Ward , N. K. Grady , C. S. Levin , N. J. Halas , Y. Wu , P. Nordlander , D. Natelson

Surface enhanced Raman scattering (SERS) exploits surface plasmons induced by the incident field in metallic nanostructures to significantly increase the Raman intensity. Graphene provides the ideal prototype two dimensional (2d) test…

Mesoscale and Nanoscale Physics · Physics 2013-04-03 F. Schedin , E. Lidorikis , A. Lombardo , V. G. Kravets , A. K. Geim , A. N. Grigorenko , K. S. Novoselov , A. C. Ferrari

The Raman scattering of light by molecular vibrations offers a powerful technique to 'fingerprint' molecules via their internal bonds and symmetries. Since Raman scattering is weak, methods to enhance, direct and harness it are highly…

We theoretically propose a new method in cavity- and surface-enhanced Raman spectroscopy (SERS) with improved temporal resolution in the measurement of stochastic Raman spectral fluctuations. Our approach combines Fourier spectroscopy and…

Optics · Physics 2025-07-02 Colburn Cobb-Bruno , Hendrik Utzat

Surface-enhanced Raman spectroscopy (SERS) is a sensitive label-free optical method that can provide fingerprint Raman spectra of biomolecules such as DNA, amino acids and proteins. While SERS of single DNA molecule has been recently…

A method is proposed to pin down an unambiguous proof for single molecule surface enhanced Raman spectroscopy (SERS). The simultaneous use of two analyte molecules enables a clear confirmation of the single (or few) molecule nature of the…

Chemical Physics · Physics 2007-05-23 E. C. Le Ru , M. Meyer , P. G. Etchegoin

The last two decades have witnessed a dramatic growth of wearable sensor technology, mainly represented by flexible, stretchable, on-skin electronic sensors that provide rich information of the wearer's health conditions and surroundings. A…

We present a microscopic model for surface-enhanced Raman scattering (SERS) from molecules adsorbed on small noble-metal nanoparticles. In the absence of direct overlap of molecular orbitals and electronic states in the metal, the main…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 Vitaliy N. Pustovit , Tigran V. Shahbazyan

Surface enhanced Raman spectroscopy (SERS) is a useful multidisciplinary analytic technique. However, it is still a challenge to produce SERS substrates that are highly sensitive, reproducible, stable, reusable, and scalable. Here, we…

Mesoscale and Nanoscale Physics · Physics 2016-07-14 Qiran Cai , Srikanth Mateti , Wenrong Yang , Rob Jones , Kenji Watanabe , Takashi Taniguchi , Shaoming Huang , Ying Chen , Lu Hua Li

This article reviews the new developments in Tip-enhanced Raman scattering (TERS). The fundamental mechanisms underlying the Raman enhancement are discussed, including the role of the plasmonic character of the metallic tips, the nature of…

Chemical Physics · Physics 2008-04-01 Catalin C. Neacsu , Samuel Berweger , Markus B. Raschke

The low efficiency of Raman spectroscopy can be overcome by placing the active molecules in the vicinity of scatterers, typically rough surfaces or nanostructures with various shapes. This surface-enhanced Raman scattering (SERS) leads to…

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