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Resective surgery may be curative for drug-resistant focal epilepsy, but only 40% to 70% of patients achieve seizure freedom after surgery. Retrospective quantitative analysis could elucidate patterns in resected structures and patient…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Fernando Pérez-García , Roman Rodionov , Ali Alim-Marvasti , Rachel Sparks , John S. Duncan , Sébastien Ourselin

Inverse reinforcement learning (IRL) aims to explicitly infer an underlying reward function based on collected expert demonstrations. Considering that obtaining expert demonstrations can be costly, the focus of current IRL techniques is on…

Machine Learning · Computer Science 2023-10-16 Lu Li , Yuxin Pan , Ruobing Chen , Jie Liu , Zilin Wang , Yu Liu , Zhiheng Li

Diffusion language models (DLMs) expose their denoising trajectories, offering a natural handle for inference-time control; accordingly, an ideal hallucination mitigation framework should intervene during generation using this model-native…

Artificial Intelligence · Computer Science 2026-04-06 Yash Shah , Abhijit Chakraborty , Naresh Kumar Devulapally , Vishnu Lokhande , Vivek Gupta

Trajectory prediction methods have demonstrated remarkable capabilities in capturing complex motion patterns. However, existing methods rely on global state assumptions, suffer from insufficient belief inference under partial observability,…

Artificial Intelligence · Computer Science 2026-05-26 Yanping Wu , Ji Zhang , Hao Chen , Edmond S. L. Ho , Chongfeng Wei

Timely and interpretable early warning of sepsis remains a major clinical challenge due to the complex temporal dynamics of physiological deterioration. Traditional data-driven models often provide accurate yet opaque predictions, limiting…

Machine Learning · Computer Science 2026-04-24 Weizhi Nie , Zhen Qu , Weijie Wang , Chunpei Li , Ke Lu , Bingyang Zhou , Hongzhi Yu

Deep learning is attracting significant interest in the neuroimaging community as a means to diagnose psychiatric and neurological disorders from structural magnetic resonance images. However, there is a tendency amongst researchers to…

Machine Learning · Computer Science 2019-10-22 David Wood , James Cole , Thomas Booth

Identifying epileptic seizures through analysis of the electroencephalography (EEG) signal becomes a standard method for the diagnosis of epilepsy. Manual seizure identification on EEG by trained neurologists is time-consuming,…

Machine Learning · Computer Science 2019-06-07 X. Yao , X. Li , Q. Ye , Y. Huang , Q. Cheng , G. -Q. Zhang

Purpose: To introduce novel dynamic structural parameters and evaluate their integration within a multimodal deep learning (DL) framework for predicting postoperative visual recovery in idiopathic full-thickness macular hole (iFTMH)…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Yinzheng Zhao , Zhihao Zhao , Rundong Jiang , Louisa Sackewitz , Quanmin Liang , Mathias Maier , Daniel Zapp , Peter Charbel Issa , Mohammad Ali Nasseri

Large language models (LLMs) offer transformative potential for clinical decision support in spine surgery but pose significant risks through hallucinations, which are factually inconsistent or contextually misaligned outputs that may…

Machine Learning · Computer Science 2025-11-21 Dong Chen , Yanzhe Wei , Zonglin He , Guan-Ming Kuang , Canhua Ye , Meiru An , Huili Peng , Yong Hu , Huiren Tao , Kenneth MC Cheung

Alzheimer's disease (AD) is a progressive neurodegenerative condition necessitating early and precise diagnosis to provide prompt clinical management. Given the paramount importance of early diagnosis, recent studies have increasingly…

Machine Learning · Computer Science 2026-02-18 Fatemeh Khalvandi , Saadat Izadi , Abdolah Chalechale

Predicting future system behaviour from past observed behaviour (time series) is fundamental to science and engineering. In computational neuroscience, the prediction of future epileptic seizures from brain activity measurements, using EEG…

Epilepsy is a chronic, noncommunicable brain disorder, and sudden seizure onsets can significantly impact patients' quality of life and health. However, wearable seizure-predicting devices are still limited, partly due to the bulky size of…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Ruifeng Zheng , Cong Chen , Shuang Wang , Yiming Liu , Lin You , Jindong Lu , Ruizhe Zhu , Guodao Zhang , Kejie Huang

Epilepsy is a disorder of the brain denoted by frequent seizures. The symptoms of seizure include confusion, abnormal staring, and rapid, sudden, and uncontrollable hand movements. Epileptic seizure detection methods involve neurological…

We present an end-to-end, interpretable, deep-learning architecture to learn a graph kernel that predicts the outcome of chronic disease drug prescription. This is achieved through a deep metric learning collaborative with a Support Vector…

Machine Learning · Computer Science 2020-08-06 Hao-Ren Yao , Der-Chen Chang , Ophir Frieder , Wendy Huang , I-Chia Liang , Chi-Feng Hung

In this work, we explore the various Brain Neuron tracking techniques, which is one of the most significant applications of Diffusion Tensor Imaging. Tractography provides us with a non-invasive method to analyze underlying tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Nandakishore Puttashamachar , Ulas Bagci

Epilepsy affects 50 million people worldwide and is one of the most common serious neurological disorders. Seizure detection and classification is a valuable tool for diagnosing and maintaining the condition. An automated classification…

Signal Processing · Electrical Eng. & Systems 2022-08-22 Scot Davidson , Niamh McCallan , Kok Yew Ng , Pardis Biglarbeigi , Dewar Finlay , Boon Leong Lan , James McLaughlin

Clinical decision support requires not only correct answers but also clinically valid reasoning. We propose Differential Reasoning Learning (DRL), a framework that improves clinical agents by learning from reasoning discrepancies. From…

Artificial Intelligence · Computer Science 2026-02-11 Jinsong Liu , Yuhang Jiang , Ramayya Krishnan , Rema Padman , Yiye Zhang , Jiang Bian

This work explores the potential utility of neural network classifiers for real-time classification of field-potential based biomarkers in next-generation responsive neuromodulation systems. Compared to classical filter-based classifiers,…

Signal Processing · Electrical Eng. & Systems 2023-01-16 Ali Kavoosi , Robert Toth , Moaad Benjaber , Mayela Zamora , Antonio Valentin , Andrew Sharott , Timothy Denison

As machine learning continues to gain momentum in the neuroscience community, we witness the emergence of novel applications such as diagnostics, characterization, and treatment outcome prediction for psychiatric and neurological disorders,…

Computer Vision and Pattern Recognition · Computer Science 2018-04-27 Maxim Sharaev , Alexander Andreev , Alexey Artemov , Alexander Bernstein , Evgeny Burnaev , Ekaterina Kondratyeva , Svetlana Sushchinskaya , Renat Akzhigitov

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…