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Bayesian design of experiments and sample size calculations usually rely on complex Monte Carlo simulations in practice. Obtaining bounds on Bayesian notions of the false-positive rate and power therefore often lack closed-form or…

Methodology · Statistics 2025-02-06 Riko Kelter , Samuel Pawel

This paper considers sequential adaptive estimation of sparse signals under a constraint on the total sensing effort. The advantage of adaptivity in this context is the ability to focus more resources on regions of space where signal…

Methodology · Statistics 2013-04-03 Dennis Wei , Alfred O. Hero

Pilot studies are often the first step of experimental research. It is usually on a smaller scale and the results can inform intervention development, study feasibility and how the study implementation will play out, if such a larger main…

Methodology · Statistics 2021-05-13 Chi-Hong Tseng , Danielle Sim

Multi-arm bandit experimental designs are increasingly being adopted over standard randomized trials due to their potential to improve outcomes for study participants, enable faster identification of the best-performing options, and/or…

Methodology · Statistics 2025-06-04 Brian M Cho , Aurélien Bibaut , Nathan Kallus

We present adaptive sequential SAA (sample average approximation) algorithms to solve large-scale two-stage stochastic linear programs. The iterative algorithm framework we propose is organized into \emph{outer} and \emph{inner} iterations…

Optimization and Control · Mathematics 2020-12-08 Raghu Pasupathy , Yongjia Song

Adaptive sample size re-estimation (SSR) is a well-established strategy for improving the efficiency and flexibility of clinical trials. Its central challenge is determining whether, and by how much, to increase the sample size at an…

Methodology · Statistics 2025-10-20 Rui Jin , Cai Wu , Qiqi Deng

Identifying subgroups, which respond differently to a treatment, both in terms of efficacy and safety, is an important part of drug development. A well-known challenge in exploratory subgroup analyses is the small sample size in the…

Computation · Statistics 2016-06-28 Marius Thomas , Björn Bornkamp

Probability proportional to size (PPS) sampling schemes with a target sample size aim to produce a sample comprising a specified number $n$ of items while ensuring that each item in the population appears in the sample with a probability…

Methodology · Statistics 2024-11-14 Brian Hentschel , Peter J. Haas , Yuanyuan Tian

Estimating sample size and statistical power is an essential part of a good study design. This R package allows users to conduct power analysis based on Monte Carlo simulations in settings in which consideration of the correlations between…

Methodology · Statistics 2024-04-16 Phuc H. Nguyen , Stephanie M. Engel , Amy H. Herring

In observational studies, accurately characterizing variance is critical for sample size determination, yet unaccounted-for variability from propensity score estimation and the resulting weights limit the accuracy of standard variance…

Methodology · Statistics 2026-04-24 Taekwon Hong , Daeyoung Lim , Woojung Bae , Yong Ma

The Ramsey sequence is a canonical example of a quantum phase measurement for a spin qubit. In Ramsey measurements, the measurement efficiency can be optimized through careful selection of settings for the phase accumulation time setting,…

Quantum Physics · Physics 2021-10-27 Robert D. McMichael , Sergey Dushenko , Sean M. Blakley

The recently proposed stochastic Polyak stepsize (SPS) and stochastic line-search (SLS) for SGD have shown remarkable effectiveness when training over-parameterized models. However, in non-interpolation settings, both algorithms only…

Machine Learning · Computer Science 2023-08-22 Xiaowen Jiang , Sebastian U. Stich

Real-world experiments involve batched & delayed feedback, non-stationarity, multiple objectives & constraints, and (often some) personalization. Tailoring adaptive methods to address these challenges on a per-problem basis is infeasible,…

Machine Learning · Computer Science 2024-11-11 Ethan Che , Daniel R. Jiang , Hongseok Namkoong , Jimmy Wang

Surrogate models have become ubiquitous in science and engineering for their capability of emulating expensive computer codes, necessary to model and investigate complex phenomena. Bayesian emulators based on Gaussian processes adequately…

Computation · Statistics 2017-08-02 A. Garbuno-Inigo , F. A. DiazDelaO , K. M. Zuev

Randomization testing is a fundamental method in statistics, enabling inferential tasks such as testing for (conditional) independence of random variables, constructing confidence intervals in semiparametric location models, and…

Methodology · Statistics 2023-03-21 Yash Nair , Lucas Janson

Adaptive experiments use preliminary analyses of the data to inform further course of action and are commonly used in many disciplines including medical and social sciences. Because the null hypothesis and experimental design are…

Methodology · Statistics 2026-05-26 Tobias Freidling , Qingyuan Zhao , Zijun Gao

With the emergence of high-throughput technologies, it is possible to measure large amounts of data relatively at low cost. Such situations arise in many fields from sciences to humanities, and variable selection may be of great help to…

Computation · Statistics 2021-08-17 Jung Nicolas , Frédéric Bertrand , Myriam Maumy-Bertrand

Design of experiments has traditionally relied on the frequentist hypothesis testing framework where the optimal size of the experiment is specified as the minimum sample size that guarantees a required level of power. Sample size…

Methodology · Statistics 2025-08-07 Shirin Golchi , Luke Hagar

A common problem in health research is that we have a large database with many variables measured on a large number of individuals. We are interested in measuring additional variables on a subsample; these measurements may be newly…

Methodology · Statistics 2022-03-22 Thomas Lumley , Tong Chen

Large Language Models (LLMs) demonstrate impressive ability in handling reasoning tasks. However, unlike humans who can instinctively adapt their problem-solving strategies to the complexity of task, most LLM-based methods adopt a…

Computation and Language · Computer Science 2024-12-24 Jianpeng Zhou , Wanjun Zhong , Yanlin Wang , Jiahai Wang