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Accurate segmentation of brain images typically requires the integration of complementary information from multiple image modalities. However, clinical data for all modalities may not be available for every patient, creating a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Haitao Li , Ziyu Li , Yiheng Mao , Zhengyao Ding , Zhengxing Huang

Accurate medical image segmentation commonly requires effective learning of the complementary information from multimodal data. However, in clinical practice, we often encounter the problem of missing imaging modalities. We tackle this…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Cheng Chen , Qi Dou , Yueming Jin , Hao Chen , Jing Qin , Pheng-Ann Heng

Deep learning models have shown promising performance for cell nucleus segmentation in the field of pathology image analysis. However, training a robust model from multiple domains remains a great challenge for cell nucleus segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Dawei Fan , Yifan Gao , Jiaming Yu , Yanping Chen , Wencheng Li , Chuancong Lin , Kaibin Li , Changcai Yang , Riqing Chen , Lifang Wei

The clinical utility of deep learning models for medical image segmentation is severely constrained by their inability to generalize to unseen domains. This failure is often rooted in the models learning spurious correlations between…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Tao Tang , Shijie Xu , Jionglong Su , Zhixiang Lu

Causal reasoning provides a language to ask important interventional and counterfactual questions beyond purely statistical association. In medical imaging, for example, we may want to study the causal effect of genetic, environmental, or…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Rajat Rasal , Daniel C. Castro , Nick Pawlowski , Ben Glocker

Multimodal 3D MRI brain tumor segmentation is a pivotal step in radiotherapy target delineation, surgical planning and post-treatment assessment. Existing methods often assume artifact-free MRI images. However, inevitable patient motion…

Image and Video Processing · Electrical Eng. & Systems 2026-05-18 Yuchun Wang , Xiaosong Li , Gefei Liang , Yang Liu

Multi-modal brain tumor segmentation typically involves four magnetic resonance imaging (MRI) modalities, while incomplete modalities significantly degrade performance. Existing solutions employ explicit or implicit modality adaptation,…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Kaixiang Yang , Wenqi Shan , Xudong Li , Xuan Wang , Xikai Yang , Xi Wang , Pheng-Ann Heng , Qiang Li , Zhiwei Wang

Multi-modal brain tumor segmentation is critical for clinical diagnosis, and it requires accurate identification of distinct internal anatomical subregions. While the recent prompt-based segmentation paradigms enable interactive experiences…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Yuxiang Luo , Qing Xu , Hai Huang , Yuqi Ouyang , Zhen Chen , Wenting Duan

Accurate brain tumor segmentation using multiparametric MRI is critical for effective treatment planning. However, in clinical settings, complete acquisition of all MRI sequences is not always possible. The absence of certain MRI modalities…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Danish Ali , Ajmal Mian , Naveed Akhtar , Ghulam Mubashar Hassan

Accurate segmentation of brain tumors in MRI scans is critical for clinical diagnosis and treatment planning. We propose a semi-supervised, two-stage framework that extends the ReCoSeg approach to the larger and more heterogeneous BraTS…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Sara Yavari , Rahul Nitin Pandya , Jacob Furst

Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents a more difficult scenario. To cope with this challenge, Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Tianyi Liu , Zhaorui Tan , Muyin Chen , Xi Yang , Haochuan Jiang , Kaizhu Huang

Purpose: Gliomas are the most common and aggressive type of brain tumors due to their infiltrative nature and rapid progression. The process of distinguishing tumor boundaries from healthy cells is still a challenging task in the clinical…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Ramy A. Zeineldin , Mohamed E. Karar , Jan Coburger , Christian R. Wirtz , Oliver Burgert

The accurate segmentation of brain tumors from multi-modal MRI is critical for clinical diagnosis and treatment planning. While integrating complementary information from various MRI sequences is a common practice, the frequent absence of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Dongqing Xie , Yonghuang Wu , Zisheng Ai , Jun Min , Zhencun Jiang , Shaojin Geng , Lei Wang

Medical multimodal representation learning aims to integrate heterogeneous clinical data into unified patient representations to support predictive modeling, which remains an essential yet challenging task in the medical data mining…

Machine Learning · Computer Science 2025-09-09 Xiaoguang Zhu , Lianlong Sun , Yang Liu , Pengyi Jiang , Uma Srivatsa , Nipavan Chiamvimonvat , Vladimir Filkov

Deep neural networks (DNNs) often struggle with out-of-distribution data, limiting their reliability in diverse realworld applications. To address this issue, domain generalization methods have been developed to learn domain-invariant…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Jiaxi Li , Di Lin , Hao Chen , Hongying Liu , Liang Wan , Wei Feng

Brain tumor segmentation based on multi-modal magnetic resonance imaging (MRI) plays a pivotal role in assisting brain cancer diagnosis, treatment, and postoperative evaluations. Despite the achieved inspiring performance by existing…

Image and Video Processing · Electrical Eng. & Systems 2022-11-16 Haoran Li , Cheng Li , Weijian Huang , Xiawu Zheng , Yan Xi , Shanshan Wang

Deep learning (DL) has recently drawn much attention in image analysis, natural language process, and high-dimensional medical data analysis. Under the causal direct acyclic graph (DAG) interpretation, the input variables without incoming…

Applications · Statistics 2022-03-22 Jong-Hyeon Jeong , Yichen Jia

We formulate a general framework for building structural causal models (SCMs) with deep learning components. The proposed approach employs normalising flows and variational inference to enable tractable inference of exogenous noise…

Machine Learning · Statistics 2020-10-26 Nick Pawlowski , Daniel C. Castro , Ben Glocker

Recent advances in machine learning and prevalence of digital medical images have opened up an opportunity to address the challenging brain tumor segmentation (BTS) task by using deep convolutional neural networks. However, different from…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Dingwen Zhang , Guohai Huang , Qiang Zhang , Jungong Han , Junwei Han , Yizhou Yu

Variational autoencoders (VAEs) and other generative methods have garnered growing interest not just for their generative properties but also for the ability to dis-entangle a low-dimensional latent variable space. However, few existing…

Machine Learning · Computer Science 2023-02-14 Sunay Bhat , Jeffrey Jiang , Omead Pooladzandi , Gregory Pottie
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