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Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

In emergency departments, rural hospitals, or clinics in less developed regions, clinicians often lack fast image analysis by trained radiologists, which can have a detrimental effect on patients' healthcare. Large Language Models (LLMs)…

Artificial Intelligence · Computer Science 2024-09-11 David Bani-Harouni , Nassir Navab , Matthias Keicher

This study reviewed the use of Large Language Models (LLMs) in healthcare, focusing on their training corpora, customization techniques, and evaluation metrics. A systematic search of studies from 2021 to 2024 identified 61 articles. Four…

Computation and Language · Computer Science 2025-02-18 Shuqi Yang , Mingrui Jing , Shuai Wang , Jiaxin Kou , Manfei Shi , Weijie Xing , Yan Hu , Zheng Zhu

Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively…

Artificial Intelligence · Computer Science 2025-05-27 William Han , Chaojing Duan , Zhepeng Cen , Yihang Yao , Xiaoyu Song , Atharva Mhaskar , Dylan Leong , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Improving the accuracy and reliability of medical coding reduces clinician burnout and supports revenue cycle processes, freeing providers to focus more on patient care. However, automating the assignment of ICD-10-CM and CPT codes from…

Domain-adapted open-weight large language models (LLMs) offer promising healthcare applications, from queryable knowledge bases to multimodal assistants, with the crucial advantage of local deployment for privacy preservation. However,…

Computation and Language · Computer Science 2025-10-22 Lara Ahrens , Wilhelm Haverkamp , Nils Strodthoff

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

Background: Large language models (LLMs) have seen extraordinary advances with applications in clinical decision support. However, high-quality evidence is urgently needed on the potential and limitation of LLMs in providing accurate…

Artificial Intelligence · Computer Science 2024-09-24 Yuxing Zhi , Yuan Guo , Kai Yuan , Hesong Wang , Heng Xu , Haina Yao , Albert C Yang , Guangrui Huang , Yuping Duan

We evaluated the viability of using a Large Language Model (LLM) to extract patient-specific specific toxicity and progression outcomes from unstructured radiology reports. We retrospectively extracted 160 follow-up CT and PET/CT electronic…

Medical Physics · Physics 2026-03-02 Justin Pijanowski , Yakout Mezgueldi , Alan Lee , Drew Moghanaki , Ricky R. Savjani , James Lamb

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

Computation and Language · Computer Science 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

Background: Advancements in large language models (LLMs) have opened new possibilities in psychiatric interviews, an underexplored area where LLMs could be valuable. This study focuses on enhancing psychiatric interviews by analyzing…

Artificial Intelligence · Computer Science 2025-02-11 Jae-hee So , Joonhwan Chang , Eunji Kim , Junho Na , JiYeon Choi , Jy-yong Sohn , Byung-Hoon Kim , Sang Hui Chu

Background Large Language Models (LLMs), enhanced with Clinical Practice Guidelines (CPGs), can significantly improve Clinical Decision Support (CDS). However, methods for incorporating CPGs into LLMs are not well studied. Methods We…

Computation and Language · Computer Science 2024-01-25 David Oniani , Xizhi Wu , Shyam Visweswaran , Sumit Kapoor , Shravan Kooragayalu , Katelyn Polanska , Yanshan Wang

Instruction-tuned Large Language Models (LLMs) have exhibited impressive language understanding and the capacity to generate responses that follow specific prompts. However, due to the computational demands associated with training these…

Computation and Language · Computer Science 2024-03-26 Yida Mu , Ben P. Wu , William Thorne , Ambrose Robinson , Nikolaos Aletras , Carolina Scarton , Kalina Bontcheva , Xingyi Song

Mobile and wearable healthcare monitoring play a vital role in facilitating timely interventions, managing chronic health conditions, and ultimately improving individuals' quality of life. Previous studies on large language models (LLMs)…

Artificial Intelligence · Computer Science 2025-10-01 Xin Wang , Ting Dang , Xinyu Zhang , Vassilis Kostakos , Michael J. Witbrock , Hong Jia

Large Language Models (LLMs) show potential for medical applications but often lack specialized clinical knowledge. Retrieval Augmented Generation (RAG) allows customization with domain-specific information, making it suitable for…

Large Language Models (LLMs) have shown significant promise across various natural language processing tasks. However, their application in the field of pathology, particularly for extracting meaningful insights from unstructured medical…

Computation and Language · Computer Science 2025-03-04 Rachit Saluja , Jacob Rosenthal , Yoav Artzi , David J. Pisapia , Benjamin L. Liechty , Mert R. Sabuncu

This study presents an innovative approach to the application of large language models (LLMs) in clinical decision-making, focusing on OpenAI's ChatGPT. Our approach introduces the use of contextual prompts-strategically designed to include…

Artificial Intelligence · Computer Science 2023-08-22 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia

Advances in Large Language Models (LLMs) have led to significant interest in their potential to support human experts across a range of domains, including public health. In this work we present automated evaluations of LLMs for public…

Large Language Models (LLMs) have become a key topic in AI and NLP, transforming sectors like healthcare, finance, education, and marketing by improving customer service, automating tasks, providing insights, improving diagnostics, and…

Artificial Intelligence · Computer Science 2025-12-05 Vignesh Kumar Kembu , Pierandrea Morandini , Marta Bianca Maria Ranzini , Antonino Nocera

Large language models (LLMs) are increasingly being used in a zero-shot fashion to assess mental health conditions, yet we have limited knowledge on what factors affect their accuracy. In this study, we utilize a clinical dataset of natural…