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Large Language Models (LLMs) have shown impressive performance on existing medical question-answering benchmarks. This high performance makes it increasingly difficult to meaningfully evaluate and differentiate advanced methods. We present…

Computation and Language · Computer Science 2025-03-21 Xiangru Tang , Daniel Shao , Jiwoong Sohn , Jiapeng Chen , Jiayi Zhang , Jinyu Xiang , Fang Wu , Yilun Zhao , Chenglin Wu , Wenqi Shi , Arman Cohan , Mark Gerstein

While agent evaluation has shifted toward long-horizon tasks, most benchmarks still emphasize local, step-level reasoning rather than the global constrained optimization (e.g., time and financial budgets) that demands genuine planning…

Artificial Intelligence · Computer Science 2026-01-27 Yinger Zhang , Shutong Jiang , Renhao Li , Jianhong Tu , Yang Su , Lianghao Deng , Xudong Guo , Chenxu Lv , Junyang Lin

Recent advances in mathematical reasoning and the long-term planning capabilities of large language models (LLMs) have precipitated the development of agents, which are being increasingly leveraged in business operations processes. Decision…

Artificial Intelligence · Computer Science 2025-08-18 Xuhua Zhao , Yuxuan Xie , Caihua Chen , Yuxiang Sun

Large language model (LLM) agents have exhibited strong problem-solving competence across domains like research and coding. Yet, it remains underexplored whether LLM agents can tackle compounding real-world problems that require a diverse…

Artificial Intelligence · Computer Science 2025-11-04 Hanwen Xu , Xuyao Huang , Yuzhe Liu , Kai Yu , Zhijie Deng

Artificial intelligence systems for scientific discovery have demonstrated remarkable potential, yet existing approaches remain largely proprietary and operate in batch-processing modes requiring hours per research cycle, precluding…

Artificial Intelligence · Computer Science 2026-01-28 Lukas Weidener , Marko Brkić , Mihailo Jovanović , Ritvik Singh , Chiara Baccin , Emre Ulgac , Alex Dobrin , Aakaash Meduri

Agentic memory systems enable large language model (LLM) agents to maintain state across long interactions, supporting long-horizon reasoning and personalization beyond fixed context windows. Despite rapid architectural development, the…

Computation and Language · Computer Science 2026-05-21 Dongming Jiang , Yi Li , Songtao Wei , Jinxin Yang , Ayushi Kishore , Alysa Zhao , Dingyi Kang , Xu Hu , Feng Chen , Qiannan Li , Bingzhe Li

Existing AutoML systems have advanced the automation of machine learning (ML); however, they still require substantial manual configuration and expert input, particularly when handling multimodal data. We introduce MLZero, a novel…

AI agents are increasingly useful for biological data analysis, but existing benchmarks mostly test broad biological knowledge, executable workflows, or localized analysis steps rather than end-to-end scientific reasoning over spatial…

Artificial Intelligence · Computer Science 2026-05-28 Ian Diks , Harihara Muralidharan , Tim Proctor , Kenny Workman

Recent advances in code generation models have unlocked unprecedented opportunities for automating feature engineering, yet their adoption in real-world ML teams remains constrained by critical challenges: (i) the scarcity of datasets…

Machine Learning · Computer Science 2026-01-19 Himanshu Thakur , Anusha Kamath , Anurag Muthyala , Dhwani Sanmukhani , Smruthi Mukund , Jay Katukuri

Large language model (LLM) agents have demonstrated strong capabilities across diverse domains, yet automated agent design remains a significant challenge. Current automated agent design approaches are often constrained by limited search…

Computation and Language · Computer Science 2025-11-21 Yu Li , Lehui Li , Zhihao Wu , Qingmin Liao , Jianye Hao , Kun Shao , Fengli Xu , Yong Li

Foundation models (FMs) are catalyzing a transformative shift in materials science (MatSci) by enabling scalable, general-purpose, and multimodal AI systems for scientific discovery. Unlike traditional machine learning models, which are…

Machine Learning · Computer Science 2025-06-27 Minh-Hao Van , Prateek Verma , Chen Zhao , Xintao Wu

We introduce Agentic Reasoning, a framework that enhances large language model (LLM) reasoning by integrating external tool-using agents. Agentic Reasoning dynamically leverages web search, code execution, and structured memory to address…

Artificial Intelligence · Computer Science 2025-07-16 Junde Wu , Jiayuan Zhu , Yuyuan Liu , Min Xu , Yueming Jin

Efficient control in long-horizon robotic manipulation is challenging due to complex representation and policy learning requirements. Model-based visual reinforcement learning (RL) has shown great potential in addressing these challenges…

Robotics · Computer Science 2025-01-27 Zixuan Chen , Jing Huo , Yangtao Chen , Yang Gao

As Large Language Models (LLMs) and other AI systems evolve, robustly estimating their capabilities from inherently stochastic outputs while systematically quantifying uncertainty in these estimates becomes increasingly important. Further,…

Artificial Intelligence · Computer Science 2025-07-15 Lennart Luettgau , Harry Coppock , Magda Dubois , Christopher Summerfield , Cozmin Ududec

Generative AI (GenAI) has transformed applications in natural language processing and content creation, yet centralized inference remains hindered by high latency, limited customizability, and privacy concerns. Deploying large models (LMs)…

Systems and Control · Electrical Eng. & Systems 2026-02-10 Haiyuan Li , Hari Madhukumar , Shuangyi Yan , Yulei Wu , Dimitra Simeonidou

The advancements of large language models (LLMs) have piqued growing interest in developing LLM-based language agents to automate scientific discovery end-to-end, which has sparked both excitement and skepticism about their true…

One of the grand challenges of artificial general intelligence is developing agents capable of conducting scientific research and discovering new knowledge. While frontier models have already been used as aides to human scientists, e.g. for…

Artificial Intelligence · Computer Science 2024-09-04 Chris Lu , Cong Lu , Robert Tjarko Lange , Jakob Foerster , Jeff Clune , David Ha

As LLM agents tackle increasingly complex tasks, a critical question is whether they can maintain strategic coherence over long horizons: planning under uncertainty, learning from delayed feedback, and adapting when early mistakes compound.…

Computation and Language · Computer Science 2026-04-02 Muyu He , Adit Jain , Anand Kumar , Vincent Tu , Soumyadeep Bakshi , Sachin Patro , Nazneen Rajani

The reasoning capabilities of LLM (Large Language Model) are widely acknowledged in recent research, inspiring studies on tool learning and autonomous agents. LLM serves as the "brain" of the agent, orchestrating multiple tools for…

Machine Learning · Computer Science 2024-03-26 Xiangyan Liu , Rongxue Li , Wei Ji , Tao Lin

Despite Large Language Models (LLMs) like GPT-4 achieving impressive results in function-level code generation, they struggle with repository-scale code understanding (e.g., coming up with the right arguments for calling routines),…