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Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

The recently emerging conditional diffusion models seem promising for mitigating the labor and expenses in building large 3D medical imaging datasets. However, previous studies on 3D CT generation primarily focus on specific organs…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Linrui Dai , Rongzhao Zhang , Yongrui Yu , Xiaofan Zhang

Two-dimensional single-slice abdominal computed tomography (CT) provides a detailed tissue map with high resolution allowing quantitative characterization of relationships between health conditions and aging. However, longitudinal analysis…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Xin Yu , Qi Yang , Yucheng Tang , Riqiang Gao , Shunxing Bao , Leon Y. Cai , Ho Hin Lee , Yuankai Huo , Ann Zenobia Moore , Luigi Ferrucci , Bennett A. Landman

We propose a cascaded 3D diffusion model framework to synthesize high-fidelity 3D PET/CT volumes directly from demographic variables, addressing the growing need for realistic digital twins in oncologic imaging, virtual trials, and…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Siyeop Yoon , Sifan Song , Pengfei Jin , Matthew Tivnan , Yujin Oh , Sekeun Kim , Dufan Wu , Xiang Li , Quanzheng Li

Spatial control methods using additional modules on pretrained diffusion models have gained attention for enabling conditional generation in natural images. These methods guide the generation process with new conditions while leveraging the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Suhyun Ahn , Wonjung Park , Jihoon Cho , Seunghyuck Park , Jinah Park

Anatomy shape modeling is a fundamental problem in medical data analysis. However, the geometric complexity and topological variability of anatomical structures pose significant challenges to accurate anatomical shape generation. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Guoqing Zhang , Jingyun Yang , Siqi Chen , Anping Zhang , Yang Li

Diffusion probabilistic models have demonstrated significant potential in generating high-quality, realistic medical images, providing a promising solution to the persistent challenge of data scarcity in the medical field. Nevertheless,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Delin An , Chaoli Wang

As a new emerging and promising type of generative models, diffusion models have proven to outperform Generative Adversarial Networks (GANs) in multiple tasks, including image synthesis. In this work, we explore semantic image synthesis for…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Yan Zhuang , Benjamin Hou , Tejas Sudharshan Mathai , Pritam Mukherjee , Boah Kim , Ronald M. Summers

The scarcity of high-quality segmentation masks remains a major bottleneck for medical image analysis, particularly in non-contrast CT (NCCT) neuroimaging, where manual annotation is costly and variable. To address this limitation, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Lucia Borrego , Vajira Thambawita , Marco Ciuffreda , Ines del Val , Alejandro Dominguez , Josep Munuera

In the realm of medical image analysis, self-supervised learning (SSL) techniques have emerged to alleviate labeling demands, while still facing the challenge of training data scarcity owing to escalating resource requirements and privacy…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Yuran Wang , Zhijing Wan , Yansheng Qiu , Zheng Wang

Fetal ultrasound (US) examinations require the acquisition of multiple planes, each providing unique diagnostic information to evaluate fetal development and screening for congenital anomalies. However, obtaining a comprehensive,…

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

The acquisition of annotated datasets with paired images and segmentation masks is a critical challenge in domains such as medical imaging, remote sensing, and computer vision. Manual annotation demands significant resources, faces ethical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Rupak Bose , Chinedu Innocent Nwoye , Aditya Bhat , Nicolas Padoy

The development of robust deep learning models for breast ultrasound (BUS) image analysis is significantly constrained by the scarcity of expert-annotated data. To address this limitation, we propose a clinically controllable generative…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Haoyu Pan , Hongxin Lin , Zetian Feng , Chuxuan Lin , Junyang Mo , Chu Zhang , Zijian Wu , Yi Wang , Qingqing Zheng

Abdominal organ segmentation from CT and MRI is an essential prerequisite for surgical planning and computer-aided navigation systems. It is challenging due to the high variability in the shape, size, and position of abdominal organs.…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Fabian Bongratz , Anne-Marie Rickmann , Christian Wachinger

The scarcity of well-annotated diverse medical images is a major hurdle for developing reliable AI models in healthcare. Substantial technical advances have been made in generative foundation models for natural images. Here we develop…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Yuanfeng Ji , Dan Lin , Xiyue Wang , Lu Zhang , Wenhui Zhou , Chongjian Ge , Ruihang Chu , Xiaoli Yang , Junhan Zhao , Junsong Chen , Xiangde Luo , Sen Yang , Jin Fang , Ping Luo , Ruijiang Li

2D low-dose single-slice abdominal computed tomography (CT) slice enables direct measurements of body composition, which are critical to quantitatively characterizing health relationships on aging. However, longitudinal analysis of body…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Xin Yu , Qi Yang , Yucheng Tang , Riqiang Gao , Shunxing Bao , LeonY. Cai , Ho Hin Lee , Yuankai Huo , Ann Zenobia Moore , Luigi Ferrucci , Bennett A. Landman

Recent works in medical image segmentation have actively explored various deep learning architectures or objective functions to encode high-level features from volumetric data owing to limited image annotations. However, most existing…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Chae Eun Lee , Minyoung Chung , Yeong-Gil Shin

Acquiring annotated data at scale with rare diseases or conditions remains a challenge. It would be extremely useful to have a method that controllably synthesizes images that can correct such underrepresentation. Assuming a proper latent…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Spyridon Thermos , Xiao Liu , Alison O'Neil , Sotirios A. Tsaftaris
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