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An important problem in the field of bioinformatics is to identify interactive effects among profiled variables for outcome prediction. In this paper, a logistic regression model with pairwise interactions among a set of binary covariates…

Artificial Intelligence · Computer Science 2016-12-30 Easton Li Xu , Xiaoning Qian , Tie Liu , Shuguang Cui

Graph-structured data exhibit substantial heterogeneity in where their predictive signals originate: in some domains, node-level semantics dominate, while in others, structural patterns play a central role. This structure-semantics…

Computation and Language · Computer Science 2026-04-03 Safal Thapaliya , Zehong Wang , Jiazheng Li , Ziming Li , Yanfang Ye , Chuxu Zhang

We study the problem of learning robust discriminative representations of causally related latent variables given the underlying causal graph and a training set comprising passively collected observational data and interventional data…

Machine Learning · Computer Science 2025-12-16 Gautam Sreekumar , Vishnu Naresh Boddeti

The trade-off between expressiveness and interpretability remains a core challenge when building human-centric predictive models for classification and decision-making. While symbolic rules offer interpretability, they often lack…

Artificial Intelligence · Computer Science 2024-06-26 Ruochen Wang , Si Si , Felix Yu , Dorothea Wiesmann , Cho-Jui Hsieh , Inderjit Dhillon

A central challenge in neuroscience is understanding how neural system implements computation through its dynamics. We propose a nonlinear time series model aimed at characterizing interpretable dynamics from neural trajectories. Our model…

Quantitative Methods · Quantitative Biology 2016-10-28 Yuan Zhao , Il Memming Park

This paper explores the intricate relationship between interpretability and robustness in deep learning models. Despite their remarkable performance across various tasks, deep learning models often exhibit critical vulnerabilities,…

Machine Learning · Computer Science 2024-12-30 Navid Nayyem , Abdullah Rakin , Longwei Wang

We investigate the data-driven discovery of constitutive closures in nonlinear reaction-diffusion systems with known governing PDE structures. Our objective is to robustly recover diffusion and reaction laws from spatiotemporal observations…

Computational Engineering, Finance, and Science · Computer Science 2026-04-03 Hanbing Liang , Ze Tao , Fujun Liu

We propose neural-symbolic integration for abstract concept explanation and interactive learning. Neural-symbolic integration and explanation allow users and domain-experts to learn about the data-driven decision making process of large…

Artificial Intelligence · Computer Science 2022-01-19 Benedikt Wagner , Artur d'Avila Garcez

Symbolic equations are at the core of scientific discovery. The task of discovering the underlying equation from a set of input-output pairs is called symbolic regression. Traditionally, symbolic regression methods use hand-designed…

Machine Learning · Computer Science 2021-06-14 Luca Biggio , Tommaso Bendinelli , Alexander Neitz , Aurelien Lucchi , Giambattista Parascandolo

Learning-based signal processing systems increasingly support high-stakes medical decisions using heterogeneous biomedical signals, including medical images, physiological time series, and clinical records. Despite strong predictive…

Signal Processing · Electrical Eng. & Systems 2026-03-02 Surajit Das , Maxine Tan

In social science, formal and quantitative models, such as ones describing economic growth and collective action, are used to formulate mechanistic explanations, provide predictions, and uncover questions about observed phenomena. Here, we…

Symbolic Computation · Computer Science 2023-08-17 Julia Balla , Sihao Huang , Owen Dugan , Rumen Dangovski , Marin Soljacic

Recently deep reinforcement learning has achieved tremendous success in wide ranges of applications. However, it notoriously lacks data-efficiency and interpretability. Data-efficiency is important as interacting with the environment is…

Machine Learning · Computer Science 2021-06-23 Duo Xu , Faramarz Fekri

There is recently a surge in approaches that learn low-dimensional embeddings of nodes in networks. As there are many large-scale real-world networks, it's inefficient for existing approaches to store amounts of parameters in memory and…

Social and Information Networks · Computer Science 2018-12-24 Zhengyan Zhang , Cheng Yang , Zhiyuan Liu , Maosong Sun , Zhichong Fang , Bo Zhang , Leyu Lin

Speculative inference is a promising paradigm employing small speculative models (SSMs) as drafters to generate draft tokens, which are subsequently verified in parallel by the target large language model (LLM). This approach enhances the…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-16 Luyao Gao , Jianchun Liu , Hongli Xu , Xichong Zhang , Yunming Liao , Liusheng Huang

Language models' (LMs) proficiency in handling deterministic symbolic reasoning and rule-based tasks remains limited due to their dependency implicit learning on textual data. To endow LMs with genuine rule comprehension abilities, we…

Computation and Language · Computer Science 2024-03-12 Yixuan Weng , Minjun Zhu , Fei Xia , Bin Li , Shizhu He , Kang Liu , Jun Zhao

Stochastic recurrent neural networks with latent random variables of complex dependency structures have shown to be more successful in modeling sequential data than deterministic deep models. However, the majority of existing methods have…

Machine Learning · Computer Science 2020-04-24 Ehsan Hajiramezanali , Arman Hasanzadeh , Nick Duffield , Krishna Narayanan , Mingyuan Zhou , Xiaoning Qian

In some situations, the interpretability of the machine learning models plays a role as important as the model accuracy. Interpretability comes from the need to trust the prediction model, verify some of its properties, or even enforce them…

Machine Learning · Computer Science 2024-04-10 Guilherme Seidyo Imai Aldeia , Fabricio Olivetti de Franca

Symbolic regression is a type of discrete optimization problem that involves searching expressions that fit given data points. In many cases, other mathematical constraints about the unknown expression not only provide more information…

Machine Learning · Computer Science 2021-02-16 Li Li , Minjie Fan , Rishabh Singh , Patrick Riley

When the system is linear, why should learning be nonlinear? Linear dynamical systems, the analytical backbone of control theory, signal processing and circuit analysis, have exact closed-form solutions via the state transition matrix. Yet…

Machine Learning · Computer Science 2026-03-31 Shafayeth Jamil , Rehan Kapadia

Evolving networks are complex data structures that emerge in a wide range of systems in science and engineering. Learning expressive representations for such networks that encode their structural connectivity and temporal evolution is…

Machine Learning · Computer Science 2024-08-26 Amirhossein Nouranizadeh , Fatemeh Tabatabaei Far , Mohammad Rahmati