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Early and accurate interpretation of screening mammograms is essential for effective breast cancer detection, yet it remains a complex challenge due to subtle imaging findings and diagnostic ambiguity. Many existing AI approaches fall short…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Yalda Zafari , Roaa Elalfy , Mohamed Mabrok , Somaya Al-Maadeed , Tamer Khattab , Essam A. Rashed

The PI-CAI (Prostate Imaging: Cancer AI) challenge led to expert-level diagnostic algorithms for clinically significant prostate cancer detection. The algorithms receive biparametric MRI scans as input, which consist of T2-weighted and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Alessa Hering , Sarah de Boer , Anindo Saha , Jasper J. Twilt , Mattias P. Heinrich , Derya Yakar , Maarten de Rooij , Henkjan Huisman , Joeran S. Bosma

The increasing deployment of artificial intelligence (AI) in clinical settings challenges foundational assumptions underlying traditional frameworks of medical evidence. Classical statistical approaches, centered on randomized controlled…

Methodology · Statistics 2026-01-07 Richik Chakraborty

Although deep learning models in medical imaging often achieve excellent classification performance, they can rely on shortcut learning, exploiting spurious correlations or confounding factors that are not causally related to the target…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Sarah Müller , Philipp Berens

The application of Deep Learning (DL) for medical diagnosis is often hampered by two problems. First, the amount of training data may be scarce, as it is limited by the number of patients who have acquired the condition to be diagnosed.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-17 Diyuan Lu , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

Reinforcement learning post-training has substantially improved the reasoning accuracy of vision-language models, yet the resulting policies remain poorly calibrated. Terminal correctness rewards provide no gradient that penalizes confident…

Machine Learning · Computer Science 2026-05-19 Peng Cui , Boyao Yang , Jun Zhu

The widespread adoption of machine learning in critical applications demands techniques to mitigate high-consequence errors. Our method utilizes a dual-classifier GBDT pipeline to distinguish routine human-like errors from high-risk…

Artificial Intelligence · Computer Science 2026-05-05 Abolfazl Mohammadi-Seif , Ricardo Baeza-Yates

Deep models, such as convolutional neural networks (CNNs) and vision transformer (ViT), demonstrate remarkable performance in image classification. However, those deep models require large data to fine-tune, which is impractical in the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Yihang Wu , Muhammad Owais , Reem Kateb , Ahmad Chaddad

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

Oral cancer is frequently diagnosed at later stages due to its similarity to other lesions. Existing research on computer aided diagnosis has made progress using deep learning; however, most approaches remain limited by small, imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Joy Naoum , Revana Salama , Ali Hamdi

Relatively abundant availability of medical imaging data has provided significant support in the development and testing of Neural Network based image processing methods. Clinicians often face issues in selecting suitable image processing…

Image and Video Processing · Electrical Eng. & Systems 2021-09-10 Mayank Goswami

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

Artificial Intelligence · Computer Science 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee

As artificial intelligence systems move toward clinical deployment, ensuring reliable prediction behavior is fundamental for safety-critical decision-making tasks. One proposed safeguard is selective prediction, where models can defer…

Machine Learning · Computer Science 2026-05-25 L. Julián Lechuga López , Farah E. Shamout , Tim G. J. Rudner

Selective classification enables models to make predictions only when they are sufficiently confident, aiming to enhance safety and reliability, which is important in high-stakes scenarios. Previous methods mainly use deep neural networks…

Machine Learning · Computer Science 2024-06-10 Yu-Chang Wu , Shen-Huan Lyu , Haopu Shang , Xiangyu Wang , Chao Qian

This paper proposes an efficient system for classifying cervical cancer cells using pre-trained convolutional neural networks (CNNs). We first fine-tune five pre-trained CNNs and minimize the overall cost of misclassification by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Ashfiqun Mustari , Rushmia Ahmed , Afsara Tasnim , Jakia Sultana Juthi , G M Shahariar

Breast cancer is one of the leading fatal disease worldwide with high risk control if early discovered. Conventional method for breast screening is x-ray mammography, which is known to be challenging for early detection of cancer lesions.…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Essam A. Rashed , M. Samir Abou El Seoud

While state-of-the-art models for breast cancer detection leverage multi-view mammograms for enhanced diagnostic accuracy, they often focus solely on visual mammography data. However, radiologists document valuable lesion descriptors that…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Gil Ben-Artzi , Feras Daragma , Shahar Mahpod

Deep learning models have achieved promising results in breast cancer classification, yet their 'black-box' nature raises interpretability concerns. This research addresses the crucial need to gain insights into the decision-making process…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Ann-Kristin Balve , Peter Hendrix

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Machine Learning · Statistics 2018-06-28 Jens Behrmann , Christian Etmann , Tobias Boskamp , Rita Casadonte , Jörg Kriegsmann , Peter Maass