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Brain tumors are serious health problems that require early diagnosis due to their high mortality rates. Diagnosing tumors by examining Magnetic Resonance Imaging (MRI) images is a process that requires expertise and is prone to error.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Mustafa Yurdakul , Şakir Taşdemir

Being cautious is crucial for enhancing the trustworthiness of machine learning systems integrated into decision-making pipelines. Although calibrated probabilities help in optimal decision-making, perfect calibration remains unattainable,…

Machine Learning · Computer Science 2024-08-12 Mari-Liis Allikivi , Joonas Järve , Meelis Kull

Noisy labels are a pervasive challenge in medical image classification, where annotation errors arise from inter-observer variability and diagnostic ambiguity. Although several noise-robust learning methods have been proposed, their…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Maycon R. S. Pereira , Filipe R. Cordeiro

Instance segmentation plays a pivotal role in medical image analysis by enabling precise localization and delineation of lesions, tumors, and anatomical structures. Although deep learning models such as Mask R-CNN and BlendMask have…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Mengxia Dai , Wenqian Luo , Tianyang Li

Artificial intelligence (AI) systems accelerate medical workflows and improve diagnostic accuracy in healthcare, serving as second-opinion systems. However, the unpredictability of AI errors poses a significant challenge, particularly in…

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

Recent brain tumor classification methods often report high accuracy but rely on deep, over-parameterized architectures with limited interpretability, making it difficult to determine whether predictions are driven by tumor-relevant…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Rajan Das Gupta , Md Imrul Hasan Showmick , Lei Wei , Mushfiqur Rahman Abir , Shanjida Akter , Md. Yeasin Rahat , Md. Jakir Hossen

Skin cancer is also one of the most common and dangerous types of cancer in the world that requires timely and precise diagnosis. In this paper, a deep-learning architecture of the multi-class skin lesion classification on the HAM10000…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Md. Maksudul Haque , Rahnuma Akter , A S M Ahsanul Sarkar Akib , Abdul Hasib

Background and objective: Employing deep learning models in critical domains such as medical imaging poses challenges associated with the limited availability of training data. We present a strategy for improving the performance and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Eva Pachetti , Sotirios A. Tsaftaris , Sara Colantonio

Deep neural networks have demonstrated promising performance on image recognition tasks. However, they may heavily rely on confounding factors, using irrelevant artifacts or bias within the dataset as the cue to improve performance. When a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Siyuan Yan , Zhen Yu , Xuelin Zhang , Dwarikanath Mahapatra , Shekhar S. Chandra , Monika Janda , Peter Soyer , Zongyuan Ge

In medical image classification tasks, it is common to find that the number of normal samples far exceeds the number of abnormal samples. In such class-imbalanced situations, reliable training of deep neural networks continues to be a major…

Machine Learning · Computer Science 2022-04-06 Sivaramakrishnan Rajaraman , Prasanth Ganesan , Sameer Antani

Uncertainty quantification is becoming increasingly important in image segmentation, especially for high-stakes applications like medical imaging. While conformal risk control generalizes conformal prediction beyond standard miscoverage to…

Machine Learning · Computer Science 2025-04-11 Rui Luo , Zhixin Zhou

With the advance of deep learning, much progress has been made in building powerful artificial intelligence (AI) systems for automatic Chest X-ray (CXR) analysis. Most existing AI models are trained to be a binary classifier with the aim of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Xiangyu Peng , Kai Wang , Jianfei Yang , Yingying Zhu , Yang You

Prostate cancer diagnosis through MR imaging have currently relied on radiologists' interpretation, whilst modern AI-based methods have been developed to detect clinically significant cancers independent of radiologists. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2026-01-09 Xiangcen Wu , Yipei Wang , Qianye Yang , Natasha Thorley , Shonit Punwani , Veeru Kasivisvanathan , Ester Bonmati , Yipeng Hu

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Accurate brain tumor segmentation from MRI scans is critical for diagnosis and treatment planning. Despite the strong performance of recent deep learning approaches, two fundamental limitations remain: (1) the lack of reliable uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Bahram Mohammadi , Yanqiu Wu , Vu Minh Hieu Phan , Sam White , Minh-Son To , Jian Yang , Michael Sheng , Yang Song , Yuankai Qi

This work reveals undiscovered challenges in the performance and generalizability of deep learning models. We (1) identify spurious shortcuts and evaluation issues that can inflate performance and (2) propose training and analysis methods…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Trevor Tsue , Brent Mombourquette , Ahmed Taha , Thomas Paul Matthews , Yen Nhi Truong Vu , Jason Su

Accurate uncertainty quantification is critical for reliable predictive modeling. Existing methods typically address either aleatoric uncertainty due to measurement noise or epistemic uncertainty resulting from limited data, but not both in…

Machine Learning · Statistics 2026-03-04 Ilia Azizi , Juraj Bodik , Jakob Heiss , Bin Yu

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier