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Open-sourcing foundation models (FMs) enables broad reuse but also exposes model trainers to economic and safety risks from unrestricted downstream fine-tuning. We address this problem by building non-fine-tunable foundation models: models…

Machine Learning · Computer Science 2026-02-03 Ziyao Wang , Nizhang Li , Pingzhi Li , Guoheng Sun , Tianlong Chen , Ang Li

Ensuring equitable Artificial Intelligence (AI) in healthcare demands systems that make unbiased decisions across all demographic groups, bridging technical innovation with ethical principles. Foundation Models (FMs), trained on vast…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Dilermando Queiroz , Anderson Carlos , André Anjos , Lilian Berton

Foundation models (FMs) are recognized as a transformative breakthrough that has started to reshape the future of artificial intelligence (AI) across both academia and industry. The integration of FMs into wireless networks is expected to…

Networking and Internet Architecture · Computer Science 2026-01-07 Han Zhang , Mohammad Farzanullah , Mohammad Ghassemi , Akram Bin Sediq , Ali Afana , Melike Erol-Kantarci

Hybrid quantum-high performance computing (Q-HPC) workflows are emerging as a key strategy for running quantum applications at scale in current noisy intermediate-scale quantum (NISQ) devices. These workflows must operate seamlessly across…

Computer simulations have long been key to understanding and designing phase-change materials (PCMs) for memory technologies. Machine learning is now increasingly being used to accelerate the modelling of PCMs, and yet it remains…

Materials Science · Physics 2025-02-13 Yuxing Zhou , Daniel F. Thomas du Toit , Stephen R. Elliott , Wei Zhang , Volker L. Deringer

In modern generative-AI workloads, matrix-vector/matrix-matrix multiplications (\emph{MatMul}) dominate the compute and energy cost. Achieving dramatic reductions in energy per token therefore requires a novel, specialized hardware that is…

Other Condensed Matter · Physics 2026-03-11 Denis Mamaluy , Md Rahatul Islam Udoy , Juan P. Mendez , Ben Feinberg , Wei Pan , Ahmedullah Aziz

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

Computing systems form the backbone of many aspects of our life, hence they are becoming as vital as water, electricity, and road infrastructures for our society. Yet, engineering long running computing systems that achieve their goals in…

Software Engineering · Computer Science 2021-08-20 Danny Weyns , Thomas Bäck , Renè Vidal , Xin Yao , Ahmed Nabil Belbachir

Pre-trained machine learning (ML) models have shown great performance for a wide range of applications, in particular in natural language processing (NLP) and computer vision (CV). Here, we study how pre-training could be used for…

Machine Learning · Computer Science 2024-01-05 Shashank Subramanian , Peter Harrington , Kurt Keutzer , Wahid Bhimji , Dmitriy Morozov , Michael Mahoney , Amir Gholami

Large Language Models (LLMs) have surged as a transformative technology for science and society, prompting governments worldwide to pursue sovereign AI capabilities that ensure data compliance and cultural representation. However, the…

Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Suraj Pai , Ibrahim Hadzic , Dennis Bontempi , Keno Bressem , Benjamin H. Kann , Andriy Fedorov , Raymond H. Mak , Hugo J. W. L. Aerts

Federated Learning (FL) has become an established technique to facilitate privacy-preserving collaborative training across a multitude of clients. However, new approaches to FL often discuss their contributions involving small deep-learning…

Machine Learning · Computer Science 2026-05-05 Herbert Woisetschläger , Alexander Isenko , Shiqiang Wang , Ruben Mayer , Hans-Arno Jacobsen

The widespread success of foundation models in natural language processing and computer vision has inspired researchers to extend the concept to scientific machine learning and computational science. However, this position paper argues that…

Despite tremendous progress in developing deep-learning-based weather forecasting systems, their design space, including the impact of different design choices, is yet to be well understood. This paper aims to fill this knowledge gap by…

Foundation models (FMs) are transforming computational pathology by offering new ways to analyze histopathology images. However, FMs typically require weeks of training on large databases, making their creation a resource-intensive process.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Till Nicke , Daniela Schacherer , Jan Raphael Schäfer , Natalia Artysh , Antje Prasse , André Homeyer , Andrea Schenk , Henning Höfener , Johannes Lotz

Foundation models offer a new opportunity to redesign existing systems and workflows with a new AI first perspective. However, operationalizing this opportunity faces several challenges and tradeoffs. The goal of this article is to offer an…

Computers and Society · Computer Science 2024-01-26 Peyman Faratin , Ray Garcia , Jacomo Corbo

Computer models are indispensable tools for understanding the Earth system. While high-resolution operational models have achieved many successes, they exhibit persistent biases, particularly in simulating extreme events and statistical…

Machine Learning · Computer Science 2025-10-16 Pouria Behnoudfar , Charlotte Moser , Marc Bocquet , Sibo Cheng , Nan Chen

High Performance Computing (HPC), Artificial Intelligence (AI)/Machine Learning (ML), and Quantum Computing (QC) and communications offer immense opportunities for innovation and impact on society. Researchers in these areas depend on…

Computers and Society · Computer Science 2020-12-18 William Gropp , Sujata Banerjee , Ian Foster

High Performance Computing (HPC) aims at providing reasonably fast computing solutions to scientific and real life problems. The advent of multicore architectures is noticeable in the HPC history, because it has brought the underlying…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-07 Claude Tadonki

Foundation models, first introduced in 2021, refer to large-scale pretrained models (e.g., large language models (LLMs) and vision-language models (VLMs)) that learn from extensive unlabeled datasets through unsupervised methods, enabling…

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