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Large language model (LLM)-based multi-agent systems have demonstrated impressive capabilities in handling complex tasks. However, the complexity of agentic behaviors makes these systems difficult to understand. When failures occur,…

Human-Computer Interaction · Computer Science 2026-02-06 Rui Sheng , Yukun Yang , Chuhan Shi , Yanna Lin , Zixin Chen , Huamin Qu , Furui Cheng

The global ageing population necessitates new and emerging strategies for caring for older adults. In this article, we explore the potential for transformation in elderly care through Agentic Artificial Intelligence (AI), powered by Large…

Artificial Intelligence · Computer Science 2025-07-22 Ruhul Amin Khalil , Kashif Ahmad , Hazrat Ali

Researchers are investing substantial effort in developing powerful general-purpose agents, wherein Foundation Models are used as modules within agentic systems (e.g. Chain-of-Thought, Self-Reflection, Toolformer). However, the history of…

Artificial Intelligence · Computer Science 2025-03-04 Shengran Hu , Cong Lu , Jeff Clune

With recent advances in Large Language Models (LLMs), Agentic AI has become phenomenal in real-world applications, moving toward multiple LLM-based agents to perceive, learn, reason, and act collaboratively. These LLM-based Multi-Agent…

Artificial Intelligence · Computer Science 2025-01-14 Khanh-Tung Tran , Dung Dao , Minh-Duong Nguyen , Quoc-Viet Pham , Barry O'Sullivan , Hoang D. Nguyen

This study reports the findings of qualitative interview sessions conducted with ICU clinicians for the co-design of a system user interface of an artificial intelligence (AI)-driven clinical decision support (CDS) system. This system…

Human-Computer Interaction · Computer Science 2025-03-13 Andrea E. Davidson , Jessica M. Ray , Ayush K. Patel , Yulia Strekalova Levites , Parisa Rashidi , Azra Bihorac

This paper introduces a methodology based on agentic workflows for economic research that leverages Large Language Models (LLMs) and multimodal AI to enhance research efficiency and reproducibility. Our approach features autonomous and…

General Economics · Economics 2025-04-15 Herbert Dawid , Philipp Harting , Hankui Wang , Zhongli Wang , Jiachen Yi

Today's conversational agents are restricted to simple standalone commands. In this paper, we present Iris, an agent that draws on human conversational strategies to combine commands, allowing it to perform more complex tasks that it has…

Human-Computer Interaction · Computer Science 2017-07-18 Ethan Fast , Binbin Chen , Julia Mendelsohn , Jonathan Bassen , Michael Bernstein

Large language models (LLMs) are increasingly used in clinical settings, raising concerns about racial bias in both generated medical text and clinical reasoning. Existing studies have identified bias in medical LLMs, but many focus on…

Computers and Society · Computer Science 2026-04-21 Sihao Xing , Zaur Gouliev

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

Data-driven scientific discovery requires the iterative integration of scientific domain knowledge, statistical expertise, and an understanding of data semantics to make nuanced analytical decisions, e.g., about which variables,…

Agentic AI systems built on large language models (LLMs) offer significant potential for automating complex workflows, from software development to customer support. However, LLM agents often underperform due to suboptimal configurations;…

The rapid advancement of large language models (LLMs) has driven the development of agentic systems capable of autonomously performing complex tasks. Despite their impressive capabilities, LLMs remain constrained by their internal knowledge…

Information Retrieval · Computer Science 2025-08-19 Wenlin Zhang , Xiaopeng Li , Yingyi Zhang , Pengyue Jia , Yichao Wang , Huifeng Guo , Yong Liu , Xiangyu Zhao

Multi-agent AI systems powered by large language models (LLMs) are increasingly applied to solve complex tasks. However, these systems often rely on fragile, manually designed prompts and heuristics, making optimization difficult. A key…

Artificial Intelligence · Computer Science 2025-02-10 Wanjia Zhao , Mert Yuksekgonul , Shirley Wu , James Zou

Recent breakthroughs in Large Language Models (LLMs) have led to the emergence of agentic AI systems that extend beyond the capabilities of standalone models. By empowering LLMs to perceive external environments, integrate multimodal…

Artificial Intelligence · Computer Science 2025-03-24 Chengkai Huang , Junda Wu , Yu Xia , Zixu Yu , Ruhan Wang , Tong Yu , Ruiyi Zhang , Ryan A. Rossi , Branislav Kveton , Dongruo Zhou , Julian McAuley , Lina Yao

Clinical decision making (CDM) is a complex, dynamic process crucial to healthcare delivery, yet it remains a significant challenge for artificial intelligence systems. While Large Language Model (LLM)-based agents have been tested on…

Computation and Language · Computer Science 2025-10-13 Jie Liu , Wenxuan Wang , Zizhan Ma , Guolin Huang , Yihang SU , Kao-Jung Chang , Wenting Chen , Haoliang Li , Linlin Shen , Michael Lyu

Autonomous Driving Systems (ADS) require diverse and safety-critical traffic scenarios for effective training and testing, but the existing data generation methods struggle to provide flexibility and scalability. We propose LASER, a novel…

Robotics · Computer Science 2024-10-25 Hao Gao , Jingyue Wang , Wenyang Fang , Jingwei Xu , Yunpeng Huang , Taolue Chen , Xiaoxing Ma

We demonstrate LLARS (LLM Assisted Research System), an open-source platform that bridges the gap between domain experts and developers for building LLM-based systems. It integrates three tightly connected modules into an end-to-end…

Artificial Intelligence · Computer Science 2026-05-12 Philipp Steigerwald , Mara Stieler , Jennifer Burghardt , Eric Rudolph , Jens Albrecht

Drug development and pharmacovigilance are frequently bottlenecked by legacy clinical reporting pipelines. These monolithic systems encode regulatory-grade logic but resist AI integration by producing opaque output with no machine-readable…

Software Engineering · Computer Science 2026-05-15 Jaime Yan

Clinical antimicrobial therapy requires the dynamic integration of pathogen profiles,host factors, pharmacological properties of antimicrobials,and the severity of infection. This complexity imposes fundamental limitations on the…

Artificial Intelligence · Computer Science 2025-11-27 Zhe Li , Yehan Qiu , Yujie Chen , Xiang Zhou

Building agents, systems that perceive and act upon their environment with a degree of autonomy, has long been a focus of AI research. This pursuit has recently become vastly more practical with the emergence of large language models (LLMs)…

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