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Multi-agent collaboration systems (MACS), powered by large language models (LLMs), solve complex problems efficiently by leveraging each agent's specialization and communication between agents. However, the inherent exchange of information…

Cryptography and Security · Computer Science 2026-03-04 Jian Cui , Zichuan Li , Luyi Xing , Xiaojing Liao

This paper introduces Agentic-AI Healthcare, a privacy-aware, multilingual, and explainable research prototype developed as a single-investigator project. The system leverages the emerging Model Context Protocol (MCP) to orchestrate…

Cryptography and Security · Computer Science 2025-10-06 Mohammed A. Shehab

Decades' advances in digital health technologies, such as electronic health records, have largely streamlined routine clinical processes. Yet, most these systems are still hard to learn and use: Clinicians often face the burden of managing…

Artificial Intelligence · Computer Science 2025-09-16 Jared Zhu , Junde Wu

Large language model (LLM) systems are increasingly used to support high-stakes decision-making, but they typically perform worse when the available evidence is internally inconsistent. Such a scenario exists in real-world healthcare…

Computation and Language · Computer Science 2026-04-02 Haochen Liu , Weien Li , Rui Song , Zeyu Li , Chun Jason Xue , Xiao-Yang Liu , Sam Nallaperuma , Xue Liu , Ye Yuan

This report describes ARIS (Auto-Research-in-sleep), an open-source research harness for autonomous research, including its architecture, assurance mechanisms, and early deployment experience. The performance of agent systems built on LLMs…

Software Engineering · Computer Science 2026-05-06 Ruofeng Yang , Yongcan Li , Shuai Li

Medical coding converts free-text clinical notes into standardized diagnostic and procedural codes, which are essential for billing, hospital operations, and medical research. Unlike ordinary text classification, it requires multi-step…

Artificial Intelligence · Computer Science 2025-11-18 Jiyang Zheng , Islam Nassar , Thanh Vu , Xu Zhong , Yang Lin , Tongliang Liu , Long Duong , Yuan-Fang Li

Clinical reasoning agents based on large language models (LLMs) aim to automate tasks such as intensive care unit (ICU) monitoring and patient state tracking from electronic health records (EHRs). Existing systems typically rely on manually…

Artificial Intelligence · Computer Science 2026-05-12 Timothy Ossowski , Xinchi Liu , Danyal Maqbool , Vaibhav Dhanuka , Sheng Zhang , Hoifung Poon , Majid Afshar , Tyler Bradshaw , Junjie Hu

Large language models (LLMs) and vision-language models (VLMs) have the potential to transform biological research by enabling autonomous experimentation. Yet, their application remains constrained by rigid protocol design, limited…

Robotics · Computer Science 2025-07-03 Yibo Qiu , Zan Huang , Zhiyu Wang , Handi Liu , Yiling Qiao , Yifeng Hu , Shu'ang Sun , Hangke Peng , Ronald X Xu , Mingzhai Sun

Accurate interpretation of clinical narratives is critical for patient care, but the complexity of these notes makes automation challenging. While Large Language Models (LLMs) show promise, single-model approaches can lack the robustness…

Artificial Intelligence · Computer Science 2025-09-01 Yeawon Lee , Xiaoyang Wang , Christopher C. Yang

Causal discovery is fundamental to scientific research, yet traditional statistical algorithms face significant challenges, including expensive data collection, redundant computation for known relations, and unrealistic assumptions. While…

Computation and Language · Computer Science 2025-10-13 Tao Feng , Lizhen Qu , Niket Tandon , Gholamreza Haffari

Health informatics research is characterized by diverse data modalities, rapid knowledge expansion, and the need to integrate insights across biomedical science, data analytics, and clinical practice. These characteristics make it…

Artificial Intelligence · Computer Science 2025-09-24 Yuxiao Cheng , Jinli Suo

Developing AI models that are useful in clinical practice, requires efficient collaboration between clinicians and AI developers. This poses a practical challenge: clinicians must repeatedly communicate and refine their requirements with AI…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Zihao Zhao , Frederik Hauke , Juliana De Castilhos , Mathis Bode , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

Clinical decision-making is inherently complex and fast-paced, particularly in emergency departments (EDs) where critical, rapid and high-stakes decisions are made. Clinical Decision Rules (CDRs) are standardized evidence-based tools that…

We present MOSAIC, a multi-agent Large Language Model (LLM) framework for solving challenging scientific coding tasks. Unlike general-purpose coding, scientific workflows require algorithms that are rigorous, interconnected with deep domain…

Computation and Language · Computer Science 2026-05-05 Siddeshwar Raghavan , Tanwi Mallick

Large visual language models (VLMs) have shown strong multi-modal medical reasoning ability, but most operate as end-to-end black boxes, diverging from clinicians' evidence-based, staged workflows and hindering clinical accountability.…

Artificial Intelligence · Computer Science 2026-03-12 Yuexi Du , Jinglu Wang , Shujie Liu , Nicha C. Dvornek , Yan Lu

Building and deploying machine learning solutions in healthcare remains expensive and labor-intensive due to fragmented preprocessing workflows, model compatibility issues, and stringent data privacy constraints. In this work, we introduce…

Artificial Intelligence · Computer Science 2025-07-25 Soorya Ram Shimgekar , Shayan Vassef , Abhay Goyal , Navin Kumar , Koustuv Saha

Agentic systems are becoming more capable: agents define strategies, take actions, and interact with different environments. This autonomy poses serious challenges for overseeing and assessing agent behavior. Most current tools are limited,…

Computation and Language · Computer Science 2026-05-22 Asaf Yehudai , Lilach Eden , Michal Shmueli-Scheuer

Enhancing clinical decision support (CDS), reducing documentation burdens, and improving patient health literacy remain persistent challenges in digital health. This paper presents an open-source, agent-based framework that integrates Large…

Software Engineering · Computer Science 2025-06-18 Abul Ehtesham , Aditi Singh , Saket Kumar

Clinical dialogue represents a complex duality requiring both the empathetic fluency of natural conversation and the rigorous precision of evidence-based medicine. While Large Language Models possess unprecedented linguistic capabilities,…

Other Quantitative Biology · Quantitative Biology 2025-12-02 Xiaoquan Zhi , Hongke Zhao , Likang Wu , Chuang Zhao , Hengshu Zhu

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta
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