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Latent generative modeling, where a pretrained autoencoder maps pixels into a latent space for the diffusion process, has become the standard strategy for Diffusion Transformers (DiT); however, the autoencoder component has barely evolved.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Boyang Zheng , Nanye Ma , Shengbang Tong , Saining Xie

High-throughput phenotypic screens generate vast microscopy image datasets that push the limits of generative models due to their large dimensionality. Despite the growing popularity of general-purpose models trained on natural images for…

Quantitative Methods · Quantitative Biology 2025-10-24 Télio Cropsal , Rocío Mercado

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Huynh Trinh Ngoc , Toan Nguyen Hai , Ba Luong Son , Long Tran Quoc

We present Deep Compression Autoencoder (DC-AE), a new family of autoencoder models for accelerating high-resolution diffusion models. Existing autoencoder models have demonstrated impressive results at a moderate spatial compression ratio…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Junyu Chen , Han Cai , Junsong Chen , Enze Xie , Shang Yang , Haotian Tang , Muyang Li , Yao Lu , Song Han

Latent diffusion models have established a new state-of-the-art in high-resolution visual generation. Integrating Vision Foundation Model priors improves generative efficiency, yet existing latent designs remain largely heuristic. These…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Hangyu Liu , Jianyong Wang , Yutao Sun

Variational Autoencoders (VAE) are probabilistic deep generative models underpinned by elegant theory, stable training processes, and meaningful manifold representations. However, they produce blurry images due to a lack of explicit…

Computer Vision and Pattern Recognition · Computer Science 2019-11-15 Prashnna K Gyawali , Rudra Saha , Linwei Wang , VSR Veeravasarapu , Maneesh Singh

Most visual generative models compress images into a latent space before applying diffusion or autoregressive modelling. Yet, existing approaches such as VAEs and foundation model aligned encoders implicitly constrain the latent space…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Sen Ye , Jianning Pei , Mengde Xu , Shuyang Gu , Chunyu Wang , Liwei Wang , Han Hu

Autoencoder (AE) is the key to the success of latent diffusion models for image and video generation, reducing the denoising resolution and improving efficiency. However, the power of AE has long been underexplored in terms of network…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Yushu Wu , Yanyu Li , Ivan Skorokhodov , Anil Kag , Willi Menapace , Sharath Girish , Aliaksandr Siarohin , Yanzhi Wang , Sergey Tulyakov

Variational autoencoders (VAEs) typically encode images into a compact latent space, reducing computational cost but introducing an optimization dilemma: a higher-dimensional latent space improves reconstruction fidelity but often hampers…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Xunzhi Xiang , Xingye Tian , Guiyu Zhang , Yabo Chen , Shaofeng Zhang , Xuebo Wang , Xin Tao , Qi Fan

We present DC-AE 1.5, a new family of deep compression autoencoders for high-resolution diffusion models. Increasing the autoencoder's latent channel number is a highly effective approach for improving its reconstruction quality. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Junyu Chen , Dongyun Zou , Wenkun He , Junsong Chen , Enze Xie , Song Han , Han Cai

Recent work leverages Vision Foundation Models as image encoders to boost the generative performance of latent diffusion models (LDMs), as their semantic feature distributions are easy to learn. However, such semantic features often lack…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Siyu Liu , Chujie Qin , Hubery Yin , Qixin Yan , Zheng-Peng Duan , Chen Li , Jing Lyu , Chun-Le Guo , Chongyi Li

Autoencoders empower state-of-the-art image and video generative models by compressing pixels into a latent space through visual tokenization. Although recent advances have alleviated the performance degradation of autoencoders under high…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Dongxu Liu , Jiahui Zhu , Yuang Peng , Haomiao Tang , Yuwei Chen , Chunrui Han , Zheng Ge , Daxin Jiang , Mingxue Liao

The recent use of diffusion prior, enhanced by pre-trained text-image models, has markedly elevated the performance of image super-resolution (SR). To alleviate the huge computational cost required by pixel-based diffusion SR, latent-based…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Feng Luo , Jinxi Xiang , Jun Zhang , Xiao Han , Wei Yang

Diffusion autoencoders (DAEs) are typically formulated as a noise prediction model and trained with a linear-$\beta$ noise schedule that spends much of its sampling steps at high noise levels. Because high noise levels are associated with…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Pramook Khungurn , Sukit Seripanitkarn , Phonphrm Thawatdamrongkit , Supasorn Suwajanakorn

Reducing token count is crucial for efficient training and inference of latent diffusion models, especially at high resolution. A common strategy is to build high-compression image tokenizers with more channels per token. However, when…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Xin Cai , Zhiyuan You , Zhoutong Zhang , Tianfan Xue

Multi-modal foundation models are typically trained on millions of pairs of natural images and text captions, frequently obtained through web-crawling approaches. Although such models depict excellent generative capabilities, they do not…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Pierre Chambon , Christian Bluethgen , Curtis P. Langlotz , Akshay Chaudhari

Video variational autoencoders (VAEs) used in latent diffusion models typically require a sufficiently large number of latent channels to ensure high-quality video reconstruction. However, recent studies have revealed that an excessive…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Jiarui Guan , Wenshuai Zhao , Zhengtao Zou , Juho Kannala , Arno Solin

Advances in latent diffusion models (LDMs) have revolutionized high-resolution image generation, but the design space of the autoencoder that is central to these systems remains underexplored. In this paper, we introduce LiteVAE, a new…

Machine Learning · Computer Science 2025-01-22 Seyedmorteza Sadat , Jakob Buhmann , Derek Bradley , Otmar Hilliges , Romann M. Weber

Diffusion probabilistic models have been shown to generate state-of-the-art results on several competitive image synthesis benchmarks but lack a low-dimensional, interpretable latent space, and are slow at generation. On the other hand,…

Machine Learning · Computer Science 2022-11-30 Kushagra Pandey , Avideep Mukherjee , Piyush Rai , Abhishek Kumar
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