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Spatially Resolved Transcriptomics (SRT) is a cutting-edge technique that captures the spatial context of cells within tissues, enabling the study of complex biological networks. Recent graph-based methods leverage both gene expression and…

Machine Learning · Computer Science 2025-06-24 Yunhak Oh , Junseok Lee , Yeongmin Kim , Sangwoo Seo , Namkyeong Lee , Chanyoung Park

Spatial transcriptomics (ST) enables gene expression mapping within anatomical context but remains costly and low-throughput. Hematoxylin and eosin (H\&E) staining offers rich morphology yet lacks molecular resolution. We present…

Spatial transcriptomics provides an unprecedented perspective for deciphering tissue spatial heterogeneity. However, high-resolution spatial transcriptomic technology remains constrained by limited gene coverage, technical complexity, and…

Biomolecules · Quantitative Biology 2026-05-19 Xinlei Huang , Weihao Dai , Zijun Qin , Xin Yu , Di Wang , Yanran Liu , Lixin Cheng , Xubin Zheng

Deformable image registration (DIR) is a cornerstone of medical image analysis, enabling spatial alignment for tasks like comparative studies and multi-modal fusion. While learning-based methods (e.g., CNNs, transformers) offer fast…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Nikita Drozdov , Marat Zinovev , Dmitry Sorokin

Spatial Transcriptomics (ST) is a technology that measures gene expression profiles within tissue sections while retaining spatial context. It reveals localized gene expression patterns and tissue heterogeneity, both of which are essential…

Quantitative Methods · Quantitative Biology 2026-03-24 Wei Zhang , Jiajun Chu , Xinci Liu , Chen Tong , Xinyue Li

Image registration with deep neural networks has become an active field of research and exciting avenue for a long standing problem in medical imaging. The goal is to learn a complex function that maps the appearance of input image pairs to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Matthew C. H. Lee , Ozan Oktay , Andreas Schuh , Michiel Schaap , Ben Glocker

Spatial transcriptomics (ST) maps gene expression within tissue at individual spots, making it a valuable resource for multimodal representation learning. Additionally, ST inherently contains rich hierarchical information both across and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Xulin Chen , Junzhou Huang

Sensor fusion has become a popular topic in robotics. However, conventional fusion methods encounter many difficulties, such as data representation differences, sensor variations, and extrinsic calibration. For example, the calibration…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Shuyi Zhou , Shuxiang Xie , Ryoichi Ishikawa , Ken Sakurada , Masaki Onishi , Takeshi Oishi

Whole-slide images (WSIs) are fundamental for computational pathology, where accurate lesion segmentation is critical for clinical decision making. Existing methods partition WSIs into discrete patches, disrupting spatial continuity and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Yunheng Wu , Wenqi Huang , Liangyi Wang , Masahiro Oda , Yuichiro Hayashi , Daniel Rueckert , Kensaku Mori

Longitudinal image registration enables studying temporal changes in brain morphology which is useful in applications where monitoring the growth or atrophy of specific structures is important. However this task is challenging due to;…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Aisha L. Shuaibu , Kieran A. Gibb , Peter A. Wijeratne , Ivor J. A. Simpson

Multimode fibers (MMFs) provide a compact, high-throughput platform for minimally invasive imaging and information transmission. However, their utility is fundamentally constrained by mode mixing, which renders image transmission spatially…

Spatial transcriptomics (ST) has revolutionised transcriptomics analysis by preserving tissue architecture, allowing researchers to study gene expression in its native spatial context. However, despite its potential, ST still faces…

Quantitative Methods · Quantitative Biology 2025-05-19 Anthony Baptista , Rosamond Nuamah , Ciro Chiappini , Anita Grigoriadis

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling high resolution gene expression profiling within tissues. However, the high cost and scarcity of high resolution ST data remain significant challenges. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

Multi-Delay single-shot arterial spin labeling (ASL) imaging provides accurate cerebral blood flow (CBF) and, in addition, arterial transit time (ATT) maps but the inherent low SNR can be challenging. Especially standard fitting using…

Segmentation of anatomical shapes from medical images has taken an important role in the automation of clinical measurements. While typical deep-learning segmentation approaches are performed on discrete voxels, the underlying objects being…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Nil Stolt-Ansó , Julian McGinnis , Jiazhen Pan , Kerstin Hammernik , Daniel Rueckert

High-quality magnetic resonance (MR) image, i.e., with near isotropic voxel spacing, is desirable in various scenarios of medical image analysis. However, many MR acquisitions use large inter-slice spacing in clinical practice. In this…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 Kai Xuan , Liping Si , Lichi Zhang , Zhong Xue , Yining Jiao , Weiwu Yao , Dinggang Shen , Dijia Wu , Qian Wang

We present ESLAM, an efficient implicit neural representation method for Simultaneous Localization and Mapping (SLAM). ESLAM reads RGB-D frames with unknown camera poses in a sequential manner and incrementally reconstructs the scene…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Mohammad Mahdi Johari , Camilla Carta , François Fleuret

With the emergence of Neural Radiance Fields (NeRF), neural implicit representations have gained widespread applications across various domains, including simultaneous localization and mapping. However, current neural implicit SLAM faces a…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Zhiyao Zhang , Yunzhou Zhang , Yanmin Wu , Bin Zhao , Xingshuo Wang , Rui Tian

Spatial transcriptomics (ST) reveals spatial heterogeneity of gene expression, yet its resolution is limited by current platforms. Recent methods enhance resolution via H&E-stained histology, but three major challenges persist: (1)…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Xuepeng Liu , Zheng Jiang , Pinan Zhu , Hanyu Liu , Chao Li

Implicit neural representation (INR) has become the standard approach for arbitrary-scale image super-resolution (ASSR). To date, no empirical study has systematically examined the effectiveness of existing methods, nor investigated the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tayyab Nasir , Daochang Liu , Ajmal Mian