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Related papers: A Framework for Longitudinal Health AI Agents

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Agentic AI seeks to endow systems with sustained autonomy, reasoning, and interaction capabilities. To realize this vision, its assumptions about agency must be complemented by explicit models of cognition, cooperation, and governance. This…

Artificial Intelligence · Computer Science 2026-02-11 Virginia Dignum , Frank Dignum

Large language model (LLM)-based AI agents are increasingly capable of complex clinical reasoning and may soon participate in medical decision-making with limited or no real-time human oversight. This shift raises fundamental questions…

Computers and Society · Computer Science 2026-03-17 Tom Bisson , Henriette Voelker , Sanddhya Jayabalan , A John Iafrate , Jakob N Kather , Jochen K Lennerz

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

Artificial Intelligence · Computer Science 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang

The rise of Large Language Models (LLMs) has enabled the development of specialized AI agents with domain-specific reasoning and interaction capabilities, particularly in healthcare. While recent frameworks simulate medical decision-making,…

Artificial Intelligence · Computer Science 2025-07-04 Tianqi Shang , Weiqing He , Charles Zheng , Lingyao Li , Li Shen , Bingxin Zhao

Testing conversational AI systems at scale across diverse domains necessitates realistic and diverse user interactions capturing a wide array of behavioral patterns. We present a novel multi-agent framework for realistic, explainable human…

Human-Computer Interaction · Computer Science 2026-01-23 Hareeshwar Karthikeyan

Agentic AI systems -- Large Language Models (LLMs) augmented with planning, tool use, memory, and long-horizon interactions -- can execute complex tasks autonomously, but their multi-step trajectories introduce new failure modes that…

Artificial Intelligence · Computer Science 2026-05-26 Jinhu Qi , Muzhi Li , Jiahong Liu , Yuqin Shu , Dianzhi Yu , Shicheng Ma , Wenqian Cui , Yiyang Zhao , Yiyi Chen , Ruoxi Jiang , Irwin King , Zenglin Xu

The shortage of doctors is creating a critical squeeze in access to medical expertise. While conversational Artificial Intelligence (AI) holds promise in addressing this problem, its safe deployment in patient-facing roles remains largely…

Artificial Intelligence · Computer Science 2025-04-11 Antoine Lizée , Pierre-Auguste Beaucoté , James Whitbeck , Marion Doumeingts , Anaël Beaugnon , Isabelle Feldhaus

This review critically distinguishes between AI Agents and Agentic AI, offering a structured, conceptual taxonomy, application mapping, and analysis of opportunities and challenges to clarify their divergent design philosophies and…

Artificial Intelligence · Computer Science 2025-10-01 Ranjan Sapkota , Konstantinos I. Roumeliotis , Manoj Karkee

AI alignment is about ensuring AI systems only pursue goals and activities that are beneficial to humans. Most of the current approach to AI alignment is to learn what humans value from their behavioural data. This paper proposes a…

Artificial Intelligence · Computer Science 2023-10-06 Pei-Yu Chen , Myrthe L. Tielman , Dirk K. J. Heylen , Catholijn M. Jonker , M. Birna van Riemsdijk

Large language models (LLMs), due to their advanced natural language capabilities, have seen significant success in applications where the user interface is usually a conversational artificial intelligence (AI) agent and engages the user…

Computation and Language · Computer Science 2025-03-10 Fei Wei , Yaliang Li , Bolin Ding

In this work, we introduce the task of life-long personalization of large language models. While recent mainstream efforts in the LLM community mainly focus on scaling data and compute for improved capabilities of LLMs, we argue that it is…

Computation and Language · Computer Science 2024-12-18 Tiannan Wang , Meiling Tao , Ruoyu Fang , Huilin Wang , Shuai Wang , Yuchen Eleanor Jiang , Wangchunshu Zhou

Although artificial intelligence (AI) shows growing promise for mental health care, current approaches to evaluating AI tools in this domain remain fragmented and poorly aligned with clinical practice, social context, and first-hand user…

Conversational agents have been showing lots of opportunities in healthcare by taking over a lot of tasks that used to be done by a human. One of the major functions of conversational healthcare agent is intervening users' daily behaviors.…

Human-Computer Interaction · Computer Science 2021-09-07 Youjin Hwang , Donghoon Shin , Sion Baek , Bongwon Suh , Joonhwan Lee

The rapid advancement of artificial intelligence (AI) systems suggests that artificial general intelligence (AGI) systems may soon arrive. Many researchers are concerned that AIs and AGIs will harm humans via intentional misuse (AI-misuse)…

Artificial Intelligence · Computer Science 2023-05-31 Catalin Mitelut , Ben Smith , Peter Vamplew

This study proposes a novel, integrative framework for patient-centered data science in the digital health era. We developed a multidimensional model that combines traditional clinical data with patient-reported outcomes, social…

Machine Learning · Computer Science 2024-08-07 Mohsen Amoei , Dan Poenaru

Online, people often recount their experiences turning to conversational AI agents (e.g., ChatGPT, Claude, Copilot) for mental health support -- going so far as to replace their therapists. These anecdotes suggest that AI agents have great…

The advent of large language models (LLMs) has catalyzed a transformative shift in artificial intelligence, paving the way for advanced intelligent agents capable of sophisticated reasoning, robust perception, and versatile action across…

Large language models and autonomous AI agents have evolved rapidly, resulting in a diverse array of evaluation benchmarks, frameworks, and collaboration protocols. Driven by the growing need for standardized evaluation and integration, we…

Artificial Intelligence · Computer Science 2026-03-10 Mohamed Amine Ferrag , Norbert Tihanyi , Merouane Debbah

With the advancement of web techniques, they have significantly revolutionized various aspects of people's lives. Despite the importance of the web, many tasks performed on it are repetitive and time-consuming, negatively impacting overall…

Artificial Intelligence · Computer Science 2025-08-06 Liangbo Ning , Ziran Liang , Zhuohang Jiang , Haohao Qu , Yujuan Ding , Wenqi Fan , Xiao-yong Wei , Shanru Lin , Hui Liu , Philip S. Yu , Qing Li

The development of artificial intelligence systems is transitioning from creating static, task-specific models to dynamic, agent-based systems capable of performing well in a wide range of applications. We propose an Interactive Agent…

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