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The release of nnU-Net marked a paradigm shift in 3D medical image segmentation, demonstrating that a properly configured U-Net architecture could still achieve state-of-the-art results. Despite this, the pursuit of novel architectures, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Fabian Isensee , Tassilo Wald , Constantin Ulrich , Michael Baumgartner , Saikat Roy , Klaus Maier-Hein , Paul F. Jaeger

Accurate cardiac ultrasound segmentation is essential for reliable assessment of ventricular function in intelligent healthcare systems. However, echocardiographic images are challenging due to low contrast, speckle noise, irregular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Zahid Ullah , Sieun Choi , Jihie Kim

In this study, we explore in depth a few under-studied topics at the intersection of uncertainty estimation and segmentation. Prior work has shown that the quality of uncertainty estimates can be very sensitive to a range of variables. As…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Michael Smith , Frank P. Ferrie

Uncertainty estimation is an essential and heavily-studied component for the reliable application of semantic segmentation methods. While various studies exist claiming methodological advances on the one hand, and successful application on…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Kim-Celine Kahl , Carsten T. Lüth , Maximilian Zenk , Klaus Maier-Hein , Paul F. Jaeger

TodevelopanovelUncertaintyQuantification (UQ) framework to estimate the uncertainty of patient survival models in the absence of ground truth, we developed and evaluated our approach based on a dataset of 1383 patients treated with…

Computer-aided diagnosis systems must make critical decisions from medical images that are often noisy, ambiguous, or conflicting, yet today's models are trained on overly simplistic labels that ignore diagnostic uncertainty. One-hot labels…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Ang Nan Gu , Michael Tsang , Hooman Vaseli , Purang Abolmaesumi , Teresa Tsang

Reliable uncertainty quantification is crucial for trustworthy decision-making and the deployment of AI models in medical imaging. While prior work has explored the ability of neural networks to quantify predictive, epistemic, and aleatoric…

Machine Learning · Statistics 2025-08-07 Simon Baur , Wojciech Samek , Jackie Ma

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Breast Ultrasound plays a vital role in cancer diagnosis as a non-invasive approach with cost-effective. In recent years, with the development of deep learning, many CNN-based approaches have been widely researched in both tumor…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Dat T. Chung , Minh-Anh Dang , Mai-Anh Vu , Minh T. Nguyen , Thanh-Huy Nguyen , Vinh Q. Dinh

Despite impressive state-of-the-art performance on a wide variety of machine learning tasks, deep learning methods can produce over-confident predictions, particularly with limited training data. Therefore, quantifying uncertainty is…

Machine Learning · Computer Science 2022-04-27 Haleh Akrami , Anand Joshi , Sergul Aydore , Richard Leahy

Medical image segmentation, particularly in the context of ultrasound data, is a crucial aspect of computer vision and medical imaging. This paper delves into the complexities of uncertainty in the segmentation process, focusing on fetal…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Shuge Lei

Uncertainty estimation of trained deep learning networks is valuable for optimizing learning efficiency and evaluating the reliability of network predictions. In this paper, we propose a method for estimating uncertainty in deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Hansang Lee , Haeil Lee , Helen Hong , Junmo Kim

The application of deep learning models to large-scale data sets requires means for automatic quality assurance. We have previously developed a fully automatic algorithm for carotid artery wall segmentation in black-blood MRI that we aim to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Elina Thibeau-Sutre , Dieuwertje Alblas , Sophie Buurman , Christoph Brune , Jelmer M. Wolterink

Organ at risk (OAR) segmentation is a crucial step for treatment planning and outcome determination in radiotherapy treatments of cancer patients. Several deep learning based segmentation algorithms have been developed in recent years,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Ilkin Isler , Curtis Lisle , Justin Rineer , Patrick Kelly , Damla Turgut , Jacob Ricci , Ulas Bagci

Cardiac segmentation is a critical task in medical imaging, essential for detailed analysis of heart structures, which is crucial for diagnosing and treating various cardiovascular diseases. With the advent of deep learning, automated…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Malitha Gunawardhana , Fangqiang Xu , Jichao Zhao

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Accurate segmentation of the left atrial (LA) and LA scars can provide valuable information to predict treatment outcomes in AF. In this paper, we proposed to automatically…

Image and Video Processing · Electrical Eng. & Systems 2023-04-28 Yuchen Zhang , Yanda Meng , Yalin Zheng

Radiotherapy is the main treatment modality for nasopharynx cancer. Delineation of Gross Target Volume (GTV) from medical images such as CT and MRI images is a prerequisite for radiotherapy. As manual delineation is time-consuming and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-28 Haochen Mei , Wenhui Lei , Ran Gu , Shan Ye , Zhengwentai Sun , Shichuan Zhang , Guotai Wang

We introduce Med-CTX, a fully transformer based multimodal framework for explainable breast cancer ultrasound segmentation. We integrate clinical radiology reports to boost both performance and interpretability. Med-CTX achieves exact…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Enobong Adahada , Isabel Sassoon , Kate Hone , Yongmin Li

Deep learning based methods for automatic organ segmentation have shown promise in aiding diagnosis and treatment planning. However, quantifying and understanding the uncertainty associated with model predictions is crucial in critical…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Jadie Adams , Shireen Y. Elhabian

The U-Net was presented in 2015. With its straight-forward and successful architecture it quickly evolved to a commonly used benchmark in medical image segmentation. The adaptation of the U-Net to novel problems, however, comprises several…