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Machine learning (ML) promises better clinical decision-making, yet opaque model behavior limits the adoption in healthcare. We propose two novel regularization techniques for ensuring the interpretability of ML models trained on real-world…

Machine Learning · Computer Science 2026-03-24 Salma Rachidi , Aso Bozorgpanah , Eric Fey , Alexander Jung

The integration of machine learning in medical image analysis can greatly enhance the quality of healthcare provided by physicians. The combination of human expertise and computerized systems can result in improved diagnostic accuracy. An…

Transparency around limitations can improve the scientific rigor of research, help ensure appropriate interpretation of research findings, and make research claims more credible. Despite these benefits, the machine learning (ML) research…

Machine Learning · Computer Science 2022-05-18 Jessie J. Smith , Saleema Amershi , Solon Barocas , Hanna Wallach , Jennifer Wortman Vaughan

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

Computation and Language · Computer Science 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

The proliferation of machine learning (ML) has drawn unprecedented interest in the study of various multimedia contents such as text, image, audio and video, among others. Consequently, understanding and learning ML-based representations…

Multimedia · Computer Science 2023-05-02 Lei Gao , Ling Guan

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Machine-learning (ML) models in flow cytometry have the potential to reduce error rates, increase reproducibility, and boost the efficiency of clinical labs. While numerous ML models for flow cytometry data have been proposed, few studies…

During a research project in which we developed a machine learning (ML) driven visualization system for non-ML experts, we reflected on interpretability research in ML, computer-supported collaborative work and human-computer interaction.…

Human-Computer Interaction · Computer Science 2022-01-19 Jesse Josua Benjamin , Christoph Kinkeldey , Claudia Müller-Birn , Tim Korjakow , Eva-Maria Herbst

Deep learning shows promise for medical image analysis but lacks interpretability, hindering adoption in healthcare. Attribution techniques that explain model reasoning may increase trust in deep learning among clinical stakeholders. This…

Machine Learning · Computer Science 2023-08-08 Yusuf Brima , Marcellin Atemkeng

Explanations have gained an increasing level of interest in the AI and Machine Learning (ML) communities in order to improve model transparency and allow users to form a mental model of a trained ML model. However, explanations can go…

Machine Learning · Computer Science 2022-10-11 Stefano Teso , Öznur Alkan , Wolfang Stammer , Elizabeth Daly

In recent years, the use of sophisticated statistical models that influence decisions in domains of high societal relevance is on the rise. Although these models can often bring substantial improvements in the accuracy and efficiency of…

Machine Learning · Computer Science 2021-04-13 Alfredo Carrillo , Luis F. Cantú , Alejandro Noriega

Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Zohaib Salahuddin , Henry C Woodruff , Avishek Chatterjee , Philippe Lambin

Research is facing a reproducibility crisis, in which the results and findings of many studies are difficult or even impossible to reproduce. This is also the case in machine learning (ML) and artificial intelligence (AI) research. Often,…

Machine Learning · Computer Science 2023-07-21 Harald Semmelrock , Simone Kopeinik , Dieter Theiler , Tony Ross-Hellauer , Dominik Kowald

Microelectronic design verification remains a critical bottleneck in device development, traditionally mitigated by expanding verification teams and computational resources. Since the late 1990s, machine learning (ML) has been proposed to…

Hardware Architecture · Computer Science 2025-03-18 Christopher Bennett , Kerstin Eder

Recent years have witnessed the rapid growth of machine learning in a wide range of fields such as image recognition, text classification, credit scoring prediction, recommendation system, etc. In spite of their great performance in…

Machine Learning · Computer Science 2021-09-20 Guandong Xu , Tri Dung Duong , Qian Li , Shaowu Liu , Xianzhi Wang

Multimodal Large Language Models (MLLMs) have tremendous potential to improve the accuracy, availability, and cost-effectiveness of healthcare by providing automated solutions or serving as aids to medical professionals. Despite promising…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Mohammad Shahab Sepehri , Zalan Fabian , Maryam Soltanolkotabi , Mahdi Soltanolkotabi

Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…

Machine Learning · Computer Science 2025-06-05 Sreejita Ghosh , Elizabeth S. Baranowski , Michael Biehl , Wiebke Arlt , Peter Tino , Kerstin Bunte

Many research fields are currently reckoning with issues of poor levels of reproducibility. Some label it a "crisis", and research employing or building Machine Learning (ML) models is no exception. Issues including lack of transparency,…

Software Engineering · Computer Science 2025-02-27 Harald Semmelrock , Tony Ross-Hellauer , Simone Kopeinik , Dieter Theiler , Armin Haberl , Stefan Thalmann , Dominik Kowald

As machine learning (ML)-based decision support tools proliferate in clinical practice, understanding how clinicians integrate personalized ML predictions alongside randomized controlled trial (RCT) evidence is critical. We designed a…

Human-Computer Interaction · Computer Science 2026-05-19 Zeshan Hussain , Barbara D. Lam , Fernando A. Acosta-Perez , Irbaz Bin Riaz , Maia Jacobs , Andrew J. Yee , David Sontag

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

Artificial Intelligence · Computer Science 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller