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With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

Multimodal Large Language Models (MLLMs) have demonstrated strong performance in visual understanding tasks, yet they often suffer from object hallucinations--generating descriptions of objects that are inconsistent with or entirely absent…

Artificial Intelligence · Computer Science 2025-05-27 Xinmiao Hu , Chun Wang , Ruihe An , ChenYu Shao , Xiaojun Ye , Sheng Zhou , Liangcheng Li

Despite the impressive capabilities of multimodal large language models (MLLMs) in vision-language tasks, they are prone to hallucinations in real-world scenarios. This paper investigates the hallucination phenomenon in MLLMs from the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Zongmeng Zhang , Wengang Zhou , Jie Zhao , Houqiang Li

Vision-Language Models (VLMs) frequently "hallucinate" - generate plausible yet factually incorrect statements - posing a critical barrier to their trustworthy deployment. In this work, we propose a new paradigm for diagnosing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Lexiang Xiong , Qi Li , Jingwen Ye , Xinchao Wang

Recently, large models have shown significant potential for smart healthcare. However, the deployment of Large Vision-Language Models (LVLMs) for clinical services is currently hindered by three critical challenges: a tendency to…

Artificial Intelligence · Computer Science 2025-10-27 Siyong Chen , Jinbo Wen , Jiawen Kang , Tenghui Huang , Xumin Huang , Yuanjia Su , Hudan Pan , Zishao Zhong , Dusit Niyato , Shengli Xie , Dong In Kim

Multimodal hallucination in multimodal large language models (MLLMs) restricts the correctness of MLLMs. However, multimodal hallucinations are multi-sourced and arise from diverse causes. Existing benchmarks fail to adequately distinguish…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Bowen Dong , Minheng Ni , Zitong Huang , Guanglei Yang , Wangmeng Zuo , Lei Zhang

Large language models (LLMs) have shown promise in clinical diagnosis but remain limited by unreliable report generation, weak evidence grounding, and opaque reasoning. We propose MedCollab, an IBIS-guided multi-agent framework for…

Multiagent Systems · Computer Science 2026-05-27 Yuqi Zhan , Xinyue Wu , Tianyu Lin , Yutong Bao , Xiaoyu Wang , Weihao Cheng , Huangwei Chen , Feiwei Qin , Zhu Zhu

As we all know, hallucinations prevail in Large Language Models (LLMs), where the generated content is coherent but factually incorrect, which inflicts a heavy blow on the widespread application of LLMs. Previous studies have shown that…

Computation and Language · Computer Science 2024-10-15 Xinping Zhao , Jindi Yu , Zhenyu Liu , Jifang Wang , Dongfang Li , Yibin Chen , Baotian Hu , Min Zhang

Large language models (LLMs) have achieved a degree of success in generating coherent and contextually relevant text, yet they remain prone to a significant challenge known as hallucination: producing information that is not substantiated…

Computation and Language · Computer Science 2024-10-28 Ray Li , Tanishka Bagade , Kevin Martinez , Flora Yasmin , Grant Ayala , Michael Lam , Kevin Zhu

Large Vision Language Models (LVLMs) are becoming increasingly important in the medical domain, yet Medical LVLMs (Med-LVLMs) frequently generate hallucinations due to limited expertise and the complexity of medical applications. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Aofei Chang , Le Huang , Parminder Bhatia , Taha Kass-Hout , Fenglong Ma , Cao Xiao

Clinical decision-making is a dynamic, interactive, and cyclic process where doctors have to repeatedly decide on which clinical action to perform and consider newly uncovered information for diagnosis and treatment. Large Language Models…

Computation and Language · Computer Science 2026-03-03 David Bani-Harouni , Chantal Pellegrini , Ege Özsoy , Nassir Navab , Matthias Keicher

Large Language Models (LLMs) are increasingly explored for legal argument generation, yet they pose significant risks of manipulation through hallucination and ungrounded persuasion, and often fail to utilize provided factual bases…

Artificial Intelligence · Computer Science 2025-10-27 Li Zhang , Kevin D. Ashley

Hallucination remains a critical challenge in large language models (LLMs), hindering the development of reliable multimodal LLMs (MLLMs). Existing solutions often rely on human intervention or underutilize the agent's ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Zhongyu Yang , Yingfang Yuan , Xuanming Jiang , Baoyi An , Wei Pang

Multimodal clinical reasoning in the field of gastrointestinal (GI) oncology necessitates the integrated interpretation of endoscopic imagery, radiological data, and biochemical markers. Despite the evident potential exhibited by Multimodal…

Multimodal Chain-of-Thought (MCoT) models have demonstrated impressive capability in complex visual reasoning tasks. Unfortunately, recent studies reveal that they suffer from severe hallucination problems due to diminished visual attention…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Ji Ma , Wei Suo , Peng Wang , Yanning Zhang

In modern medicine, clinical diagnosis relies on the comprehensive analysis of primarily textual and visual data, drawing on medical expertise to ensure systematic and rigorous reasoning. Recent advances in large Vision-Language Models…

Artificial Intelligence · Computer Science 2025-07-03 Ziyue Wang , Junde Wu , Linghan Cai , Chang Han Low , Xihong Yang , Qiaxuan Li , Yueming Jin

Multimodal Large Language Models (MLLMs) have shown impressive perception and reasoning capabilities, yet they often suffer from hallucinations -- generating outputs that are linguistically coherent but inconsistent with the context of the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Bingkui Tong , Jiaer Xia , Kaiyang Zhou

Large Language Models (LLMs) demonstrate strong performance but often lack interpretable reasoning. This paper introduces the Multi-Agent Collaboration Framework for Diverse Thinking Modes (DiMo), which enhances both performance and…

Computation and Language · Computer Science 2025-10-21 Zhixuan He , Yue Feng

Modern large language models (LLMs) like ChatGPT have shown remarkable performance on general language tasks but still struggle on complex reasoning tasks, which drives the research on cognitive behaviors of LLMs to explore human-like…

Computation and Language · Computer Science 2024-10-10 Tian Liang , Zhiwei He , Wenxiang Jiao , Xing Wang , Yan Wang , Rui Wang , Yujiu Yang , Shuming Shi , Zhaopeng Tu

Nowadays, single Large Language Model (LLM) struggles with critical issues such as hallucination and inadequate reasoning abilities. To mitigate these issues, Multi-Agent Debate (MAD) has emerged as an effective strategy, where LLM agents…

Artificial Intelligence · Computer Science 2025-07-08 Yiliu Sun , Zicheng Zhao , Sheng Wan , Chen Gong