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Distribution-to-distribution generative models support scientific imaging tasks ranging from modeling cellular perturbation responses to translating medical images across conditions. Trustworthy generation requires reliability, or…

Machine Learning · Computer Science 2026-05-22 Dongxia Wu , Yuhui Zhang , Serena Yeung-Levy , Emma Lundberg , Emily B. Fox

Understanding temporal dynamics in medical imaging is crucial for applications such as disease progression modeling, treatment planning and anatomical development tracking. However, most deep learning methods either consider only single…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Nico Albert Disch , Yannick Kirchhoff , Robin Peretzke , Maximilian Rokuss , Saikat Roy , Constantin Ulrich , David Zimmerer , Klaus Maier-Hein

Forecasting conditional stochastic nonlinear dynamical systems is a fundamental challenge repeatedly encountered across the biological and physical sciences. While flow-based models can impressively predict the temporal evolution of…

Machine Learning · Computer Science 2025-04-02 Adam P. Generale , Andreas E. Robertson , Surya R. Kalidindi

Accurate emulation of multi-scale physical systems governed by PDEs demands models that remain stable over long autoregressive rollouts while preserving fine-scale structures. Deterministic emulators produce overly-smoothed predictions,…

Flow matching trains a neural velocity field by regression against a target velocity associated with a prescribed probability path connecting a simple initial distribution to the data distribution. A central design choice is the path…

Machine Learning · Computer Science 2026-05-21 Shukai Du , Junzhe Zhang , Yiming Li

We consider the use of probabilistic neural networks for fluid flow {surrogate modeling} and data recovery. This framework is constructed by assuming that the target variables are sampled from a Gaussian distribution conditioned on the…

Fluid Dynamics · Physics 2020-10-14 Romit Maulik , Kai Fukami , Nesar Ramachandra , Koji Fukagata , Kunihiko Taira

Generating high-quality time-series data is challenging because real-world signals often exhibit multimodal patterns and multiscale dynamics, including oscillations and high-frequency variations. Flow Matching (FM) offers an efficient…

Machine Learning · Computer Science 2026-05-29 Junru Zhang , Lang Feng , Jinbo Wang , Xu Guo , Yucheng Wang , Han Yu , Min Wu , Yabo Dong , Duanqing Xu

Data-driven methods are emerging as efficient alternatives to traditional numerical forecasting, offering fast inference and lower computational cost. Yet, for complex systems, long-term accuracy often deteriorates due to error…

Machine Learning · Computer Science 2025-09-03 Hao Zhou , Sibo Cheng

We propose a Neural Hidden Markov Model (HMM) with Adaptive Granularity Attention (AGA) for high-frequency order flow modeling. The model addresses the challenge of capturing multi-scale temporal dynamics in financial markets, where…

Statistical Finance · Quantitative Finance 2026-03-24 Tianzuo Hu

Autoregressive neural network models have been used successfully for sequence generation, feature extraction, and hypothesis scoring. This paper presents yet another use for these models: allocating more computation to more difficult…

Machine Learning · Computer Science 2020-06-03 Loren Lugosch , Derek Nowrouzezahrai , Brett H. Meyer

Autoregressive models (ARMs) currently hold state-of-the-art performance in likelihood-based modeling of image and audio data. Generally, neural network based ARMs are designed to allow fast inference, but sampling from these models is…

Machine Learning · Computer Science 2020-07-09 Auke Wiggers , Emiel Hoogeboom

Associative memories in the brain receive and store patterns of activity registered by the sensory neurons, and are able to retrieve them when necessary. Due to their importance in human intelligence, computational models of associative…

Machine Learning · Computer Science 2021-09-17 Tommaso Salvatori , Yuhang Song , Yujian Hong , Simon Frieder , Lei Sha , Zhenghua Xu , Rafal Bogacz , Thomas Lukasiewicz

We introduce a new generative modeling framework, \textbf{Flow Matching with Arbitrary Auxiliary Paths (AuxPath-FM)}, which generalizes conditional flow matching by incorporating an auxiliary variable drawn from an arbitrary distribution…

Machine Learning · Computer Science 2026-05-08 Xin Peng , Ang Gao

3D human reaction generation faces three main challenges:(1) high motion fidelity, (2) real-time inference, and (3) autoregressive adaptability for online scenarios. Existing methods fail to meet all three simultaneously. We propose…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Zichen Geng , Zeeshan Hayder , Wei Liu , Hesheng Wang , Ajmal Mian

Brain aging synthesis is a critical task with broad applications in clinical and computational neuroscience. The ability to predict the future structural evolution of a subject's brain from an earlier MRI scan provides valuable insights…

Machine Learning · Computer Science 2025-08-01 Ridvan Yesiloglu , Wei Peng , Md Tauhidul Islam , Ehsan Adeli

Flow matching models have shown great potential in image generation tasks among probabilistic generative models. However, most flow matching models in the literature do not explicitly utilize the underlying clustering structure in the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Anirban Samaddar , Yixuan Sun , Viktor Nilsson , Sandeep Madireddy

Brain activity is intrinsically a neural dynamic process constrained by anatomical space. This leads to significant variations in spatial distribution patterns and correlation patterns of neural activity across variable and heterogeneous…

Machine Learning · Computer Science 2026-03-10 Hongjie Jiang , Yifei Tang , Shuqiang Wang

One of the predominant methods for training world models is autoregressive prediction in the output space of the next element of a sequence. In Natural Language Processing (NLP), this takes the form of Large Language Models (LLMs)…

Machine Learning · Computer Science 2024-06-14 Alexi Gladstone , Ganesh Nanduru , Md Mofijul Islam , Aman Chadha , Jundong Li , Tariq Iqbal

Autoregressive language modeling (ALM) have been successfully used in self-supervised pre-training in Natural language processing (NLP). However, this paradigm has not achieved comparable results with other self-supervised approach in…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Yu Qi , Fan Yang , Yousong Zhu , Yufei Liu , Liwei Wu , Rui Zhao , Wei Li

Conditional flow matching (CFM) stands out as an efficient, simulation-free approach for training flow-based generative models, achieving remarkable performance for data generation. However, CFM is insufficient to ensure accuracy in…

Machine Learning · Computer Science 2026-02-03 Yuhao Huang , Taos Transue , Shih-Hsin Wang , William Feldman , Hong Zhang , Bao Wang