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Decision-making in personalized medicine such as cancer therapy or critical care must often make choices for dosage combinations, i.e., multiple continuous treatments. Existing work for this task has modeled the effect of multiple…

Machine Learning · Computer Science 2023-10-30 Jonas Schweisthal , Dennis Frauen , Valentyn Melnychuk , Stefan Feuerriegel

We develop methodology for a multistage decision problem with flexible number of stages in which the rewards are survival times that are subject to censoring. We present a novel Q-learning algorithm that is adjusted for censored data and…

Statistics Theory · Mathematics 2012-05-31 Yair Goldberg , Michael R. Kosorok

When safety is formulated as a limit of cumulative cost, safe reinforcement learning (RL) aims to learn policies that maximize return subject to the cost constraint in data collection and deployment. Off-policy safe RL methods, although…

Machine Learning · Computer Science 2026-03-26 Guopeng Li , Matthijs T. J. Spaan , Julian F. P. Kooij

Reinforcement learning is a popular method of finding optimal solutions to complex problems. Algorithms like Q-learning excel at learning to solve stochastic problems without a model of their environment. However, they take longer to solve…

Artificial Intelligence · Computer Science 2024-04-25 Jan Diekhoff , Jörn Fischer

Sequential detection of independent anomalous processes among K processes is considered. At each time, only M processes can be observed, and the observations from each chosen process follow two different distributions, depending on whether…

Information Theory · Computer Science 2023-07-19 Kobi Cohen , Qing Zhao

Many real-world combinatorial problems involve uncertain parameters, which can be predicted given contextual features and historical data. These `predict-then-optimize' or `contextual optimization' problems have gained significant…

Machine Learning · Computer Science 2026-05-19 Noah Schutte , Senne Berden , Tias Guns , Krzysztof Postek , Neil Yorke-Smith

This paper investigates the challenges of optimal online policy learning under missing data. State-of-the-art algorithms implicitly assume that rewards are always observable. I show that when rewards are missing at random, the Upper…

Econometrics · Economics 2025-07-29 Filippo Palomba

We give an efficient algorithm for learning a binary function in a given class C of bounded VC dimension, with training data distributed according to P and test data according to Q, where P and Q may be arbitrary distributions over X. This…

Machine Learning · Computer Science 2021-02-17 Adam Kalai , Varun Kanade

Preferential Bayesian optimization allows optimization of objectives that are either expensive or difficult to measure directly, by relying on a minimal number of comparative evaluations done by a human expert. Generating candidate…

Doubly robust learning offers a robust framework for causal inference from observational data by integrating propensity score and outcome modeling. Despite its theoretical appeal, practical adoption remains limited due to perceived…

Machine Learning · Statistics 2024-07-09 Hlynur Davíð Hlynsson

The goal of coreset selection in supervised learning is to produce a weighted subset of data, so that training only on the subset achieves similar performance as training on the entire dataset. Existing methods achieved promising results in…

Machine Learning · Computer Science 2023-01-25 Xiao Zhou , Renjie Pi , Weizhong Zhang , Yong Lin , Tong Zhang

Quantitative disease severity scoring in medical imaging is costly, time-consuming, and subject to inter-reader variability. At the same time, clinical archives contain far more longitudinal imaging data than expert-annotated severity…

Predictive models are often used for real-time decision making. However, typical machine learning techniques ignore feature evaluation cost, and focus solely on the accuracy of the machine learning models obtained utilizing all the features…

Machine Learning · Computer Science 2014-08-19 Leilani Battle , Edward Benson , Aditya Parameswaran , Eugene Wu

Positive--Unlabeled (PU) learning considers settings in which only positive and unlabeled data are available, while negatives are missing or left unlabeled. This situation is common in real applications where annotating reliable negatives…

Machine Learning · Computer Science 2025-10-30 Miao Zhang , Junpeng Li , Changchun Hua , Yana Yang

The presence of label noise often misleads the training of deep neural networks. Departing from the recent literature which largely assumes the label noise rate is only determined by the true label class, the errors in human-annotated…

Machine Learning · Computer Science 2021-03-31 Zhaowei Zhu , Tongliang Liu , Yang Liu

Distributionally robust policy learning aims to find a policy that performs well under the worst-case distributional shift, and yet most existing methods for robust policy learning consider the worst-case joint distribution of the covariate…

Machine Learning · Computer Science 2025-06-03 Jingyuan Wang , Zhimei Ren , Ruohan Zhan , Zhengyuan Zhou

Choosing optimal (or at least better) policies is an important problem in domains from medicine to education to finance and many others. One approach to this problem is through controlled experiments/trials - but controlled experiments are…

Artificial Intelligence · Computer Science 2018-02-26 Onur Atan , William R. Zame , M van der Schaar

Optimal designs are usually model-dependent and likely to be sub-optimal if the postulated model is not correctly specified. In practice, it is common that a researcher has a list of candidate models at hand and a design has to be found…

Statistics Theory · Mathematics 2023-03-29 Mingyao Ai , Holger Dette , Zhengfu Liu , Jun Yu

Linear dynamical systems that obey stochastic differential equations are canonical models. While optimal control of known systems has a rich literature, the problem is technically hard under model uncertainty and there are hardly any…

Systems and Control · Electrical Eng. & Systems 2023-06-09 Mohamad Kazem Shirani Faradonbeh , Mohamad Sadegh Shirani Faradonbeh

We propose a reinforcement learning based approach to tackle the cost-sensitive learning problem where each input feature has a specific cost. The acquisition process is handled through a stochastic policy which allows features to be…

Machine Learning · Computer Science 2016-07-14 Gabriella Contardo , Ludovic Denoyer , Thierry Artières