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Recently, a lot of automated white blood cells (WBC) or leukocyte classification techniques have been developed. However, all of these methods only utilize a single modality microscopic image i.e. either blood smear or fluorescence based,…

Image and Video Processing · Electrical Eng. & Systems 2022-08-18 Litao Yang , Deval Mehta , Dwarikanath Mahapatra , Zongyuan Ge

White blood cells (WBCs) play a crucial role in safeguarding the human body against pathogens and foreign substances. Leveraging the abundance of WBC imaging data and the power of deep learning algorithms, automated WBC analysis has the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-23 Aditya Shankar Pal , Debojyoti Biswas , Joy Mahapatra , Debasis Banerjee , Prantar Chakrabarti , Utpal Garain

Machine learning (ML) and deep learning (DL) models have been employed to significantly improve analyses of medical imagery, with these approaches used to enhance the accuracy of prediction and classification. Model predictions and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Rabia Asghar , Sanjay Kumar , Paul Hynds , Arslan Shaukat

Accurate segmentation and classification of white blood cells (WBCs) in microscopic images are essential for diagnosis and monitoring of many hematological disorders, yet remain challenging due to staining variability, complex backgrounds,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Zekriyapanah Gashti , Mostafa Mohammadpour , Ghasem Farjamnia

creating automated processes in different areas of medical science with the application of engineering tools is a highly growing field over recent decades. In this context, many medical image processing and analyzing researchers use…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Hamed Talebi , Amin Ranjbar , Alireza Davoudi , Hamed Gholami , Mohammad Bagher Menhaj

Deep learning models have gained remarkable performance on a variety of image classification tasks. However, many models suffer from limited performance in clinical or medical settings when data are imbalanced. To address this challenge, we…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Margarita L. Zuley , Shandong Wu

White blood cells (WBCs) are the most diverse cell types observed in the healing process of injured skeletal muscles. In the course of healing, WBCs exhibit dynamic cellular response and undergo multiple protein expression changes. The…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Yang Jiao , Hananeh Derakhshan , Barbara St. Pierre Schneider , Emma Regentova , Mei Yang

In this paper, we describe our method for the ISIC 2019 Skin Lesion Classification Challenge. The challenge comes with two tasks. For task 1, skin lesions have to be classified based on dermoscopic images. For task 2, dermoscopic images and…

Computer Vision and Pattern Recognition · Computer Science 2019-10-10 Nils Gessert , Maximilian Nielsen , Mohsin Shaikh , René Werner , Alexander Schlaefer

The precise categorization of white blood cell (WBC) is crucial for diagnosing blood-related disorders. However, manual analysis in clinical settings is time-consuming, labor-intensive, and prone to errors. Numerous studies have employed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Yuzhuo Chen , Zetong Chen , Yunuo An , Chenyang Lu , Xu Qiao

Leukemia (blood cancer) is an unusual spread of White Blood Cells or Leukocytes (WBCs) in the bone marrow and blood. Pathologists can diagnose leukemia by looking at a person's blood sample under a microscope. They identify and categorize…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Mohammad Zolfaghari , Hedieh Sajedi

Diagnosis of hematological malignancies depends on accurate identification of white blood cells in peripheral blood smears. Deep learning techniques are emerging as a viable solution to scale and optimize this process by automatic cell…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Michael Deutges , Ario Sadafi , Nassir Navab , Carsten Marr

Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Saqib Nazir , Ardhendu Behera

Class imbalance is a critical issue in image classification that significantly affects the performance of deep recognition models. In this work, we first identify a network degeneration dilemma that hinders the model learning by introducing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Zhiwei Zhang

Accurate classification of blood cells plays a key role in improving automated blood analysis for both medical and veterinary applications. This work presents a two-stage deep clustering method for classifying blood cells from…

Quantitative Methods · Quantitative Biology 2025-09-25 Mihaela Macarie-Ancau , Adrian Groza

White balance (WB) correction in scenes with multiple illuminants remains a persistent challenge in computer vision. Recent methods explored fusion-based approaches, where a neural network linearly blends multiple sRGB versions of an input…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 David Serrano-Lozano , Aditya Arora , Luis Herranz , Konstantinos G. Derpanis , Michael S. Brown , Javier Vazquez-Corral

The accurate classification of white blood cells and related blood components is crucial for medical diagnoses. While traditional manual examinations and automated hematology analyzers have been widely used, they are often slow and prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Alexander Kim , Ryan Kim

The examination of blood samples at a microscopic level plays a fundamental role in clinical diagnostics, influencing a wide range of medical conditions. For instance, an in-depth study of White Blood Cells (WBCs), a crucial component of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Satoshi Tsutsui , Winnie Pang , Bihan Wen

Class imbalance is a problem of significant importance in applied deep learning where trained models are exploited for decision support and automated decisions in critical areas such as health and medicine, transportation, and finance. The…

Machine Learning · Computer Science 2020-12-07 Colin Bellinger , Roberto Corizzo , Nathalie Japkowicz

Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Baomin Wang , Geng Hu , Dan Chen , Lihua Hu , Cheng Li , Yu An , Guiping Hu , Guang Jia