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Cell segmentation in histopathological images is vital for diagnosis, and treatment of several diseases. Annotating data is tedious, and requires medical expertise, making it difficult to employ supervised learning. Instead, we study a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Aayush Kumar Tyagi , Vaibhav Mishra , Prathosh A. P. , Mausam

Semantic segmentation of microscopic cell images using deep learning is an important technique, however, it requires a large number of images and ground truth labels for training. To address the above problem, we consider an efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Sota Kato , Kazuhiro Hotta

Most state-of-the-art instance segmentation methods have to be trained on densely annotated images. While difficult in general, this requirement is especially daunting for biomedical images, where domain expertise is often required for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Adrian Wolny , Qin Yu , Constantin Pape , Anna Kreshuk

Deep learning provides us with powerful methods to perform nucleus or cell segmentation with unprecedented quality. However, these methods usually require large training sets of manually annotated images, which are tedious and expensive to…

Image and Video Processing · Electrical Eng. & Systems 2023-01-11 Thomas Bonte , Maxence Philbert , Emeline Coleno , Edouard Bertrand , Arthur Imbert , Thomas Walter

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Fang Hu , Xuexue Sun , Ke Qing , Fenxi Xiao , Zhi Wang , Xiaolu Fan

Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Tyler Ward , Aaron Moseley , Abdullah-Al-Zubaer Imran

Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Rituparna Sarkar , Suvadip Mukherjee , Elisabeth Labruyère , Jean-Christophe Olivo-Marin

Unsupervised semantic segmentation aims to categorize each pixel in an image into a corresponding class without the use of annotated data. It is a widely researched area as obtaining labeled datasets is expensive. While previous works in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-01 Yau Shing Jonathan Cheung , Xi Chen , Lihe Yang , Hengshuang Zhao

Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Peilin Zhou , Bo Du , Yongchao Xu

Being able to segment unseen classes not observed during training is an important technical challenge in deep learning, because of its potential to reduce the expensive annotation required for semantic segmentation. Prior zero-label…

Computer Vision and Pattern Recognition · Computer Science 2021-04-26 Giuseppe Pastore , Fabio Cermelli , Yongqin Xian , Massimiliano Mancini , Zeynep Akata , Barbara Caputo

Instance segmentation is a fundamental vision task that aims to recognize and segment each object in an image. However, it requires costly annotations such as bounding boxes and segmentation masks for learning. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Xinlong Wang , Zhiding Yu , Shalini De Mello , Jan Kautz , Anima Anandkumar , Chunhua Shen , Jose M. Alvarez

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

Tracking cells and detecting mitotic events in time-lapse microscopy image sequences is a crucial task in biomedical research. However, it remains highly challenging due to dividing objects, low signal-tonoise ratios, indistinct boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Zhu Chen , Mert Edgü , Er Jin , Johannes Stegmaier

Self-supervised learning (SSL) can be used to solve complex visual tasks without human labels. Self-supervised representations encode useful semantic information about images, and as a result, they have already been used for tasks such as…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Paul Engstler , Luke Melas-Kyriazi , Christian Rupprecht , Iro Laina

Is self-supervised deep learning (DL) for medical image analysis already a serious alternative to the de facto standard of end-to-end trained supervised DL? We tackle this question for medical image classification, with a particular focus…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Maximilian Nielsen , Laura Wenderoth , Thilo Sentker , René Werner

Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

In the field of semi-supervised medical image segmentation, the shortage of labeled data is the fundamental problem. How to effectively learn image features from unlabeled images to improve segmentation accuracy is the main research…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Zhanhong Qiu , Haitao Gan , Ming Shi , Zhongwei Huang , Zhi Yang

Deep learning methods show promising results for overlapping cervical cell instance segmentation. However, in order to train a model with good generalization ability, voluminous pixel-level annotations are demanded which is quite expensive…

Computer Vision and Pattern Recognition · Computer Science 2020-07-22 Yanning Zhou , Hao Chen , Huangjing Lin , Pheng-Ann Heng

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

Instance segmentation of surgical instruments is a long-standing research problem, crucial for the development of many applications for computer-assisted surgery. This problem is commonly tackled via fully-supervised training of deep…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Luca Sestini , Benoit Rosa , Elena De Momi , Giancarlo Ferrigno , Nicolas Padoy