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Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Medical question answering (QA) benchmarks often focus on multiple-choice or fact-based tasks, leaving open-ended answers to real patient questions underexplored. This gap is particularly critical in mental health, where patient questions…

Computation and Language · Computer Science 2026-05-15 Yahan Li , Jifan Yao , John Bosco S. Bunyi , Adam C. Frank , Angel Hsing-Chi Hwang , Ruishan Liu

Small language models (SLMs), despite their widespread adoption in modern smart devices, have received significantly less academic attention compared to their large language model (LLM) counterparts, which are predominantly deployed in data…

Computation and Language · Computer Science 2025-02-27 Zhenyan Lu , Xiang Li , Dongqi Cai , Rongjie Yi , Fangming Liu , Xiwen Zhang , Nicholas D. Lane , Mengwei Xu

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

As Large Language Models (LLMs) become integrated into daily life, they are increasingly used for personal queries, including Sexual and Reproductive Health (SRH), allowing users to chat anonymously without fear of judgment. However,…

Large language models (LLMs) have demonstrated emergent abilities in text generation, question answering, and reasoning, facilitating various tasks and domains. Despite their proficiency in various tasks, LLMs like PaLM 540B and Llama-3.1…

Computation and Language · Computer Science 2024-12-31 Fali Wang , Zhiwei Zhang , Xianren Zhang , Zongyu Wu , Tzuhao Mo , Qiuhao Lu , Wanjing Wang , Rui Li , Junjie Xu , Xianfeng Tang , Qi He , Yao Ma , Ming Huang , Suhang Wang

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Large Language Models are essential coding assistants, yet their training is predominantly English-centric. In this study, we evaluate the performance of code language models in non-English contexts, identifying challenges in their adoption…

Open-weight versions of large language models (LLMs) are rapidly advancing, with state-of-the-art models like DeepSeek-V3 now performing comparably to proprietary LLMs. This progression raises the question of whether small open-weight LLMs…

Computation and Language · Computer Science 2025-09-24 Damian Stachura , Joanna Konieczna , Artur Nowak

When deploying large language models (LLMs), it is important to ensure that these models are not only capable, but also reliable. Many benchmarks have been created to track LLMs' growing capabilities, however there has been no similar focus…

Machine Learning · Computer Science 2025-02-06 Joshua Vendrow , Edward Vendrow , Sara Beery , Aleksander Madry

Small open-source medical large language models (LLMs) offer promising opportunities for low-resource deployment and broader accessibility. However, their evaluation is often limited to accuracy on medical multiple choice question (MCQ)…

Computation and Language · Computer Science 2026-01-21 Vanessa D'Amario , Randy Daniel , Alessandro Zanetti , Dhruv Edamadaka , Nitya Alaparthy , Joshua Tarkoff

This study investigates the reliability and validity of five advanced Large Language Models (LLMs), Claude 3.5, DeepSeek v2, Gemini 2.5, GPT-4, and Mistral 24B, for automated essay scoring in a real world higher education context. A total…

Computers and Society · Computer Science 2025-08-05 Andrea Gaggioli , Giuseppe Casaburi , Leonardo Ercolani , Francesco Collova' , Pietro Torre , Fabrizio Davide

This study provides the first comprehensive assessment of consistency and reproducibility in Large Language Model (LLM) outputs in finance and accounting research. We evaluate how consistently LLMs produce outputs given identical inputs…

General Finance · Quantitative Finance 2025-09-16 Julian Junyan Wang , Victor Xiaoqi Wang

Large language models (LLMs) are increasingly used for medical consultation and health information support. In this high-stakes setting, safety depends not only on medical knowledge, but also on how models respond when patient inputs are…

Computation and Language · Computer Science 2026-04-01 Yahan Li , Xinyi Jie , Wanjia Ruan , Xubei Zhang , Huaijie Zhu , Yicheng Gao , Chaohao Du , Ruishan Liu

Universal healthcare access is critically needed, especially in resource-limited settings. Large Language Models (LLMs) offer promise for democratizing healthcare with advanced diagnostics, but their reliability requires thorough…

Computation and Language · Computer Science 2025-03-17 Krishna Subedi

Medical Large Language Models (LLMs) are increasingly deployed for clinical decision support across diverse specialties, yet systematic evaluation of their robustness to adversarial misuse and privacy leakage remains inaccessible to most…

Cryptography and Security · Computer Science 2025-12-10 Jinghao Wang , Ping Zhang , Carter Yagemann

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

This study evaluates the capacity of large language models (LLMs) to generate structured clinical consultation templates for electronic consultation. Using 145 expert-crafted templates developed and routinely used by Stanford's eConsult…

Large Language Models(LLMs) hold promise for improving healthcare access in low-resource settings, but their effectiveness in African primary care remains underexplored. We present a methodology for creating a benchmark dataset and…

The growing use of large language models (LLMs) for biomedical question answering raises concerns about the accuracy and evidentiary support of their responses. To address this, we present Answered with Evidence, a framework for evaluating…

Machine Learning · Computer Science 2025-07-08 Julian D Baldwin , Christina Dinh , Arjun Mukerji , Neil Sanghavi , Saurabh Gombar