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Generating clinical reports that summarize abnormal patterns, diagnostic findings, and clinical interpretations from long-term EEG recordings remains labor-intensive. We present CELM, the first clinical EEG-to-Language foundation model…

Machine Learning · Computer Science 2026-05-15 Jathurshan Pradeepkumar , Zheng Chen , Jimeng Sun

To perform effective causal inference in high-dimensional datasets, initiating the process with causal discovery is imperative, wherein a causal graph is generated based on observational data. However, obtaining a complete and accurate…

Machine Learning · Computer Science 2025-04-18 Elahe Khatibi , Mahyar Abbasian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani

Continuous electroencephalography (EEG) is routinely used in neurocritical care to monitor seizures and other harmful brain activity, including rhythmic and periodic patterns that are clinically significant. Although deep learning methods…

Human-Computer Interaction · Computer Science 2026-01-05 Argha Kamal Samanta , Deepak Mewada , Monalisa Sarma , Debasis Samanta

Electrocardiogram (ECG) monitoring is one of the most powerful technique of cardiovascular disease (CVD) early identification, and the introduction of intelligent wearable ECG devices has enabled daily monitoring. However, due to the need…

Signal Processing · Electrical Eng. & Systems 2024-03-08 Hongxiang Gao , Xingyao Wang , Zhenghua Chen , Min Wu , Jianqing Li , Chengyu Liu

Client perceptions of the therapeutic alliance are critical for counseling effectiveness. Accurately capturing these perceptions remains challenging, as traditional post-session questionnaires are burdensome and often delayed, while…

Computation and Language · Computer Science 2026-02-25 Anqi Li , Chenxiao Wang , Yu Lu , Renjun Xu , Lizhi Ma , Zhenzhong Lan

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

Deep learning has significantly advanced electrocardiogram (ECG) analysis, enabling automatic annotation, disease screening, and prognosis beyond traditional clinical capabilities. However, understanding these models remains a challenge,…

Machine Learning · Computer Science 2025-09-19 Ahcène Boubekki , Konstantinos Patlatzoglou , Joseph Barker , Fu Siong Ng , Antônio H. Ribeiro

Vision-Language Models (VLMs) have enabled interpretable medical diagnosis by integrating visual perception with linguistic reasoning. Yet, existing medical chain-of-thought (CoT) models lack explicit mechanisms to represent and enforce…

Artificial Intelligence · Computer Science 2026-05-29 Jianxin Lin , Chunzheng Zhu , Peter J. Kneuertz , Yunfei Bai , Yuan Xue

Deep learning-based electrocardiogram (ECG) classification has shown impressive performance but clinical adoption has been slowed by the lack of transparent and faithful explanations. Post hoc methods such as saliency maps may fail to…

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by integrating their parametric knowledge with external retrieved content. However, knowledge conflicts caused by internal inconsistencies or noisy retrieved content…

Computation and Language · Computer Science 2025-07-03 Juan Chen , Baolong Bi , Wei Zhang , Jingyan Sui , Xiaofei Zhu , Yuanzhuo Wang , Lingrui Mei , Shenghua Liu

LLM agents excel when environments are mostly static and the needed information fits in a model's context window, but they often fail in open-ended investigations where explanations must be constructed by iteratively mining evidence from…

Artificial Intelligence · Computer Science 2026-01-30 Saurabh Jha , Rohan Arora , Bhavya , Noah Zheutlin , Paulina Toro Isaza , Laura Shwartz , Yu Deng , Daby Sow , Ruchi Mahindru , Ruchir Puri

Compiler auto-tuning faces a dichotomy between traditional black-box search methods, which lack semantic guidance, and recent Large Language Model (LLM) approaches, which often suffer from superficial pattern matching and causal opacity. In…

Machine Learning · Computer Science 2026-02-03 Haolin Pan , Lianghong Huang , Jinyuan Dong , Mingjie Xing , Yanjun Wu

Electroencephalography (EEG) interpretation using multimodal large language models (MLLMs) offers a novel approach for analyzing brain signals. However, the complex nature of brain activity introduces critical challenges: EEG signals…

Signal Processing · Electrical Eng. & Systems 2025-10-02 Ziyi Zeng , Zhenyang Cai , Yixi Cai , Xidong Wang , Junying Chen , Rongsheng Wang , Yipeng Liu , Siqi Cai , Benyou Wang , Zhiguo Zhang , Haizhou Li

Diagnosing hepatic diseases accurately and interpretably is critical, yet it remains challenging in real-world clinical settings. Existing AI approaches for clinical diagnosis often lack transparency, structured reasoning, and…

Artificial Intelligence · Computer Science 2026-03-06 Zheng Li , Jiayi Xu , Zhikai Hu , Hechang Chen , Lele Cong , Yunyun Wang , Shuchao Pang

Medical care follows complex clinical pathways that extend beyond isolated physician-patient encounters, emphasizing decision-making and transitions between different stages. Current benchmarks focusing on static exams or isolated dialogues…

Artificial Intelligence · Computer Science 2025-12-15 Yakun Zhu , Zhongzhen Huang , Qianhan Feng , Linjie Mu , Yannian Gu , Shaoting Zhang , Qi Dou , Xiaofan Zhang

Large language models (LLMs) have shown great potential in decision-making due to the vast amount of knowledge stored within the models. However, these pre-trained models are prone to lack reasoning abilities and are difficult to adapt to…

Machine Learning · Computer Science 2025-06-02 Wei Chen , Jiahao Zhang , Haipeng Zhu , Boyan Xu , Zhifeng Hao , Keli Zhang , Junjian Ye , Ruichu Cai

Randomized experiments or randomized controlled trials (RCTs) are gold standards for causal inference, yet cost and sample-size constraints limit power. We introduce CALM (Causal Analysis leveraging Language Models), a statistical framework…

Methodology · Statistics 2025-12-09 Xinrui Ruan , Xinwei Ma , Yingfei Wang , Waverly Wei , Jingshen Wang

Understanding the process of emotion generation is crucial for analyzing the causes behind emotions. Causal Emotion Entailment (CEE), an emotion-understanding task, aims to identify the causal utterances in a conversation that stimulate the…

Computation and Language · Computer Science 2024-05-22 Zhaopei Huang , Jinming Zhao , Qin Jin

Multimodal large language models (MLLMs) demonstrate considerable potential in clinical diagnostics, a domain that inherently requires synthesizing complex visual and textual data alongside consulting authoritative medical literature.…

Computation and Language · Computer Science 2026-03-23 Yannian Gu , Zhongzhen Huang , Linjie Mu , Xizhuo Zhang , Shaoting Zhang , Xiaofan Zhang

Large Language Models (LLMs) and causal learning each hold strong potential for clinical decision making (CDM). However, their synergy remains poorly understood, largely due to the lack of systematic benchmarks evaluating their integration…

Machine Learning · Computer Science 2025-11-14 Linna Wang , Zhixuan You , Qihui Zhang , Jiunan Wen , Ji Shi , Yimin Chen , Yusen Wang , Fanqi Ding , Ziliang Feng , Li Lu
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