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The surge in popularity of large language models (LLMs) has opened doors for new approaches to the creation of interactive agents. However, managing and interpreting the temporal behavior of such agents over the course of a potentially…

Artificial Intelligence · Computer Science 2024-08-29 Raven Rothkopf , Hannah Tongxin Zeng , Mark Santolucito

Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

Computation and Language · Computer Science 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship. Identifying cancer patients at risk of heart failure (HF) is critical to improving cancer treatment outcomes and safety. This study…

Machine Learning · Computer Science 2024-11-05 Ziyi Chen , Mengyuan Zhang , Mustafa Mohammed Ahmed , Yi Guo , Thomas J. George , Jiang Bian , Yonghui Wu

Radiology visual question answering (RVQA) provides precise answers to questions about chest X-ray images, alleviating radiologists' workload. While recent methods based on multimodal large language models (MLLMs) and retrieval-augmented…

Artificial Intelligence · Computer Science 2025-08-06 Ziruo Yi , Jinyu Liu , Ting Xiao , Mark V. Albert

Large Language Model (LLM) agents deployed in complex real-world scenarios increasingly operate as spatially distributed entities. However, this physical dispersion constrains agents to limited local perception and finite temporal horizons.…

Multiagent Systems · Computer Science 2026-03-18 Handi Chen , Running Zhao , Xiuzhe Wu , Edith C. H. Ngai

Large language models (LLMs) exhibit strong reasoning capabilities but typically require expensive post-training to reach high performance. Recent test-time alignment methods offer a lightweight alternative, but have been explored mainly…

Computation and Language · Computer Science 2026-03-20 Arushi Rai , Qiang Zhang , Hanqing Zeng , Yunkai Zhang , Dipesh Tamboli , Xiangjun Fan , Zhuokai Zhao , Lizhu Zhang

The growing demand for on-device large language model (LLM) inference highlights the need for efficient mobile edge computing (MEC) solutions, especially in resource-constrained settings. Speculative decoding offers a promising solution by…

Machine Learning · Computer Science 2025-12-01 Jungyeon Koh , Hyun Jong Yang

Recent advances in Large Language Model (LLM) agents have demonstrated their promising general capabilities. However, their performance in specialized real-world domains often degrades due to challenges in effectively integrating external…

Computation and Language · Computer Science 2025-10-10 Yuzheng Cai , Siqi Cai , Yuchen Shi , Zihan Xu , Lichao Chen , Yulei Qin , Xiaoyu Tan , Gang Li , Zongyi Li , Haojia Lin , Yong Mao , Ke Li , Xing Sun

Recent progress in large language models (LLMs) has enabled tool-augmented agents capable of solving complex real-world tasks through step-by-step reasoning. However, existing evaluations often focus on general-purpose or multimodal…

Despite the outstanding capabilities of large language models (LLMs), knowledge-intensive reasoning still remains a challenging task due to LLMs' limitations in compositional reasoning and the hallucination problem. A prevalent solution is…

Computation and Language · Computer Science 2025-09-29 Amy Xin , Jinxin Liu , Zijun Yao , Zhicheng Lee , Shulin Cao , Lei Hou , Juanzi Li

Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and…

Artificial Intelligence · Computer Science 2026-03-24 Wenxian Yang , Hanzheng Qiu , Bangqun Zhang , Chengquan Li , Zhiyong Huang , Xiaobin Feng , Rongshan Yu , Jiahong Dong

Traditional diagnosis of chronic diseases involves in-person consultations with physicians to identify the disease. However, there is a lack of research focused on predicting and developing application systems using clinical notes and blood…

Software Engineering · Computer Science 2024-06-27 Chun-Chieh Liao , Wei-Ting Kuo , I-Hsuan Hu , Yen-Chen Shih , Jun-En Ding , Feng Liu , Fang-Ming Hung

Recently, Diffusion Large Language Models (dLLMs) have demonstrated unique efficiency advantages, enabled by their inherently parallel decoding mechanism and flexible generation paradigm. Meanwhile, despite the rapid advancement of Search…

Artificial Intelligence · Computer Science 2026-02-10 Jiahao Zhao , Shaoxuan Xu , Zhongxiang Sun , Fengqi Zhu , Jingyang Ou , Yuling Shi , Chongxuan Li , Xiao Zhang , Jun Xu

Monitoring autonomous large language model (LLM) agents for covert malicious behavior is challenging due to delayed, context-dependent, and long-horizon attack patterns. Agents may pursue hidden objectives while maintaining superficially…

Machine Learning · Computer Science 2026-05-26 Nesreen K. Ahmed , Nima Nafisi

Medical Decision-Making (MDM) is a complex process requiring substantial domain-specific expertise to effectively synthesize heterogeneous and complicated clinical information. While recent advancements in Large Language Models (LLMs) show…

Artificial Intelligence · Computer Science 2025-08-20 Liuxin Bao , Zhihao Peng , Xiaofei Zhou , Runmin Cong , Jiyong Zhang , Yixuan Yuan

Despite the recent advancements in NLP with the advent of Large Language Models (LLMs), Entity Linking (EL) for historical texts remains challenging due to linguistic variation, noisy inputs, and evolving semantic conventions. Existing…

Computation and Language · Computer Science 2026-01-14 Cristian Santini , Marieke Van Erp , Mehwish Alam

Background: Modern large language models (LLMs) offer powerful reasoning that converts narratives into structured, taxonomy-aligned data, revealing patterns across planning, delivery, and verification. Embedded as agentic tools, LLMs can…

Large Language Models (LLMs) demonstrate strong generalization and reasoning abilities, making them well-suited for complex decision-making tasks such as medical consultation (MC). However, existing LLM-based methods often fail to capture…

Computation and Language · Computer Science 2025-10-13 Zhihao Jia , Mingyi Jia , Junwen Duan , Jianxin Wang

Improving large language models (LLMs) for electronic health record (EHR) reasoning is essential for enabling accurate and generalizable clinical predictions. While LLMs excel at medical text understanding, they underperform on EHR-based…

Artificial Intelligence · Computer Science 2025-08-20 Yue Fang , Yuxin Guo , Jiaran Gao , Hongxin Ding , Xinke Jiang , Weibin Liao , Yongxin Xu , Yinghao Zhu , Zhibang Yang , Liantao Ma , Junfeng Zhao , Yasha Wang

Large language models (LLMs) exhibit strong symbolic and compositional reasoning, yet they struggle with time series question answering as the data is typically transformed into an LLM-compatible modality, e.g., serialized text, plotted…

Artificial Intelligence · Computer Science 2026-04-08 Penghang Liu , Elizabeth Fons , Annita Vapsi , Mohsen Ghassemi , Svitlana Vyetrenko , Daniel Borrajo , Vamsi K. Potluru , Manuela Veloso