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Medical image segmentation is crucial for clinical diagnosis, yet existing models are limited by their reliance on explicit human instructions and lack the active reasoning capabilities to understand complex clinical questions. While recent…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Yu Huang , Zelin Peng , Yichen Zhao , Piao Yang , Xiaokang Yang , Wei Shen

Despite significant progress in pixel-level medical image analysis, existing medical image segmentation models rarely explore medical segmentation and diagnosis tasks jointly. However, it is crucial for patients that models can provide…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Lingran Song , Yucheng Zhou , Jianbing Shen

We present SimpleSeg, a strikingly simple yet highly effective approach to endow Multimodal Large Language Models (MLLMs) with native pixel-level perception. Our method reframes segmentation as a simple sequence generation problem: the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Tianhui Song , Haoyu Lu , Hao Yang , Lin Sui , Haoning Wu , Zaida Zhou , Zhiqi Huang , Yiping Bao , Y. Charles , Xinyu Zhou , Limin Wang

We explore the feasibility and potential of building a ground-truth-free evaluation model to assess the quality of segmentations generated by the Segment Anything Model (SAM) and its variants in medical imaging. This evaluation model…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Ahjol Senbi , Tianyu Huang , Fei Lyu , Qing Li , Yuhui Tao , Wei Shao , Qiang Chen , Chengyan Wang , Shuo Wang , Tao Zhou , Yizhe Zhang

Semi-supervised learning (SSL) for medical image segmentation is a challenging yet highly practical task, which reduces reliance on large-scale labeled dataset by leveraging unlabeled samples. Among SSL techniques, the weak-to-strong…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Shiao Xie , Hongyi Wang , Ziwei Niu , Hao Sun , Shuyi Ouyang , Yen-Wei Chen , Lanfen Lin

Semi-supervised learning (SSL) has emerged as an effective paradigm for medical image segmentation, reducing the reliance on extensive expert annotations. Meanwhile, vision-language models (VLMs) have demonstrated strong generalization and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Jiaqi Guo , Mingzhen Li , Hanyu Su , Santiago López , Lexiaozi Fan , Daniel Kim , Aggelos Katsaggelos

Current open-source Large Multimodal Models (LMMs) excel at tasks such as open-vocabulary language grounding and segmentation but can suffer under false premises when queries imply the existence of something that is not actually present in…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Tsung-Han Wu , Giscard Biamby , David Chan , Lisa Dunlap , Ritwik Gupta , Xudong Wang , Joseph E. Gonzalez , Trevor Darrell

Recent advances in MLLMs are reframing segmentation from fixed-category prediction to instruction-grounded localization. While reasoning based segmentation has progressed rapidly in natural scenes, remote sensing lacks a generalizable…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Lifan Jiang , Yuhang Pei , oxi Wu , Yan Zhao , Tianrun Wu , Shulong Yu , Lihui Zhang , Deng Cai

Recently, automated medical image segmentation methods based on deep learning have achieved great success. However, they heavily rely on large annotated datasets, which are costly and time-consuming to acquire. Few-shot learning aims to…

Artificial Intelligence · Computer Science 2024-08-20 Jiayu Huo , Ruiqiang Xiao , Haotian Zheng , Yang Liu , Sebastien Ourselin , Rachel Sparks

Universal medical image segmentation models have emerged as a promising paradigm due to their strong generalizability across diverse tasks, showing great potential for a wide range of clinical applications. This potential has been partly…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Yanwu Yang , Guinan Su , Jiesi Hu , Francesco Sammarco , Jonas Geiping , Thomas Wolfers

Reference Expression Segmentation (RES) aims to segment image regions specified by referring expressions and has become popular with the rise of multimodal large models (MLLMs). While MLLMs excel in semantic understanding, their…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Jingchao Wang , Zhijian Wu , Dingjiang Huang , Yefeng Zheng , Hong Wang

We present LlamaSeg, a visual autoregressive framework that unifies multiple image segmentation tasks via natural language instructions. We reformulate image segmentation as a visual generation problem, representing masks as "visual" tokens…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Jiru Deng , Tengjin Weng , Tianyu Yang , Wenhan Luo , Zhiheng Li , Wenhao Jiang

Over the past few years, the rapid development of deep learning technologies for computer vision has significantly improved the performance of medical image segmentation (MedISeg). However, the diverse implementation strategies of various…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Dong Zhang , Yi Lin , Hao Chen , Zhuotao Tian , Xin Yang , Jinhui Tang , Kwang Ting Cheng

Medical large language models (LLMs) achieve impressive performance on standardized benchmarks, yet these evaluations fail to capture the complexity of real clinical encounters where patients exhibit memory gaps, limited health literacy,…

Artificial Intelligence · Computer Science 2026-04-14 Sina Mansouri , Mohit Marvania , Vibhavari Ashok Shihorkar , Han Ngoc Tran , Kazhal Shafiei , Mehrdad Fazli , Yikuan Li , Ziwei Zhu

In clinical practice, segmenting specific lesions based on the needs of physicians can significantly enhance diagnostic accuracy and treatment efficiency. However, conventional lesion segmentation models lack the flexibility to distinguish…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shuyi Ouyang , Jinyang Zhang , Xiangye Lin , Xilai Wang , Qingqing Chen , Yen-Wei Chen , Lanfen Lin

Generalized Referring Expression Segmentation (GRES) extends the scope of classic RES to refer to multiple objects in one expression or identify the empty targets absent in the image. GRES poses challenges in modeling the complex spatial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Zhuofan Xia , Dongchen Han , Yizeng Han , Xuran Pan , Shiji Song , Gao Huang

While deep learning models have become the predominant method for medical image segmentation, they are typically not capable of generalizing to unseen segmentation tasks involving new anatomies, image modalities, or labels. Given a new…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Victor Ion Butoi , Jose Javier Gonzalez Ortiz , Tianyu Ma , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Medical vision--language models (VLMs) are usually evaluated on intact image--question pairs, but trustworthy clinical use requires a stronger property: a model must recognise when the evidential basis for an answer has failed. We study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Hanqi Jiang , Junhao Chen , Mingyu Kang , Hyeokjae Kwon , Yi Pan , Lifeng Chen , Weihang You , Haozhen Gong , Ruiyu Yan , Jinglei Lv , Lin Zhao , Hui Ren , Quanzheng Li , Tianming Liu , Xiang Li

Recent advances in Vision Language Models (VLMs) and Vision Foundation Models (VFMs) have opened new opportunities for zero-shot text-guided segmentation of remote sensing imagery. However, most existing approaches still rely on additional…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Jose Sosa , Danila Rukhovich , Anis Kacem , Djamila Aouada

Medical imaging has witnessed remarkable progress but usually requires a large amount of high-quality annotated data which is time-consuming and costly to obtain. To alleviate this burden, semi-supervised learning has garnered attention as…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Qingyue Wei , Lequan Yu , Xianhang Li , Wei Shao , Cihang Xie , Lei Xing , Yuyin Zhou
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