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The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

The multifactorial etiology of autism spectrum disorder (ASD) suggests that its study would benefit greatly from multimodal approaches that combine data from widely varying platforms, e.g., neuroimaging, genetics, and clinical…

Quantitative Methods · Quantitative Biology 2023-08-11 Nicha C. Dvornek , Catherine Sullivan , James S. Duncan , Abha R. Gupta

Lumbar disc herniation (LDH) is a common musculoskeletal disease that requires magnetic resonance imaging (MRI) for effective clinical management. However, the interpretation of MRI images heavily relies on the expertise of radiologists,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Lingrui Zhang , Liang Guo , Xiao An , Feng Lin , Binlong Zheng , Jiankun Wang , Zhirui Li

Deep learning has revolutionized biomedical research by providing sophisticated methods to handle complex, high-dimensional data. Multimodal deep learning (MDL) further enhances this capability by integrating diverse data types such as…

Machine Learning · Computer Science 2026-03-13 Valerio Guarrasi , Fatih Aksu , Camillo Maria Caruso , Francesco Di Feola , Aurora Rofena , Filippo Ruffini , Paolo Soda

Background: Mental illnesses such as depression and anxiety require improved methods for early detection and personalized intervention. Traditional predictive models often rely on unimodal data or early fusion strategies that fail to…

Machine Learning · Computer Science 2025-07-22 Youcef Barkat , Dylan Hamitouche , Deven Parekh , Ivy Guo , David Benrimoh

Multimodal remote sensing object detection aims to achieve more accurate and robust perception under challenging conditions by fusing complementary information from different modalities. However, existing approaches that rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Jianhong Han , Yupei Wang , Yuan Zhang , Liang Chen

A major challenge in multimodal learning is the presence of noise within individual modalities. This noise inherently affects the resulting multimodal representations, especially when these representations are obtained through explicit…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Mohammad Zia Ur Rehman , Devraj Raghuvanshi , Umang Jain , Shubhi Bansal , Nagendra Kumar

On the increase of major depressive disorders (MDD), many researchers paid attention to their recognition and treatment. Existing MDD recognition algorithms always use a single time-frequency domain method method, but the single…

Neurons and Cognition · Quantitative Biology 2021-11-03 Xiaofang Sun , Xiangwei Zheng , Yonghui Xu , Lizhen Cui , Bin Hu

Classification and identification of the materials lying over or beneath the Earth's surface have long been a fundamental but challenging research topic in geoscience and remote sensing (RS) and have garnered a growing concern owing to the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 Danfeng Hong , Lianru Gao , Naoto Yokoya , Jing Yao , Jocelyn Chanussot , Qian Du , Bing Zhang

Accurately detecting Alzheimer's disease (AD) and predicting mini-mental state examination (MMSE) score are important tasks in elderly health by magnetic resonance imaging (MRI). Most of the previous methods on these two tasks are based on…

Image and Video Processing · Electrical Eng. & Systems 2023-07-10 Xu Tian , Jin Liu , Hulin Kuang , Yu Sheng , Jianxin Wang , The Alzheimer's Disease Neuroimaging Initiative

Cognitive decline is highly heterogeneous across individuals, which complicates prognosis, trial design, and treatment planning. We present the Personalized Cognitive Decline Assessment Digital Twin (PCD-DT), a multimodal and…

Artificial Intelligence · Computer Science 2026-05-01 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

Mild Cognitive Impairment (MCI) serves as a prodromal stage of Alzheimer's Disease (AD), where early identification and intervention can effectively slow the progression to dementia. However, diagnosing AD remains a significant challenge in…

Artificial Intelligence · Computer Science 2025-11-07 Yutao Jin , Haowen Xiao , Junyong Zhai , Yuxiao Li , Jielei Chu , Fengmao Lv , Yuxiao Li

In the field of multimodal segmentation, the correlation between different modalities can be considered for improving the segmentation results. Considering the correlation between different MR modalities, in this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2021-11-10 Tongxue Zhou , Su Ruan , Pierre Vera , Stéphane Canu

Algorithmic detection of facial palsy offers the potential to improve current practices, which usually involve labor-intensive and subjective assessments by clinicians. In this paper, we present a multimodal fusion-based deep learning model…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Heng Yim Nicole Oo , Min Hun Lee , Jeong Hoon Lim

Magnetic Resonance Imaging (MRI) is widely recognized as the most reliable tool for detecting tumors due to its capability to produce detailed images that reveal their presence. However, the accuracy of diagnosis can be compromised when…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Zahid Ullah , Dragan Pamucar , Jihie Kim

Current Computer-Aided Diagnosis (CAD) methods mainly depend on medical images. The clinical information, which usually needs to be considered in practical clinical diagnosis, has not been fully employed in CAD. In this paper, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Songxiao Yang , Xiabi Liu , Zhongshu Zheng , Wei Wang , Xiaohong Ma

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete…

Machine Learning · Computer Science 2026-05-13 Camillo Maria Caruso , Valerio Guarrasi , Paolo Soda

Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang