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The joint interpretation of multi-modal and multi-view fundus images is critical for retinopathy prevention, as different views can show the complete 3D eyeball field and different modalities can provide complementary lesion areas. Compared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yonghao Huang , Leiting Chen , Chuan Zhou

Accurate identification of late-life depression (LLD) using structural brain MRI is essential for monitoring disease progression and facilitating timely intervention. However, existing learning-based approaches for LLD detection are often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Yuzhen Gao , Qianqian Wang , Yongheng Sun , Cui Wang , Yongquan Liang , Mingxia Liu

Depression and post traumatic stress disorder (PTSD) often co-occur with connected symptoms, complicating automated assessment, which is often binary and disorder specific. Clinically useful diagnosis needs severity aware cross disorder…

Computation and Language · Computer Science 2025-10-24 Filippo Cenacchi , Deborah Richards , Longbing Cao

Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Jun-En Ding , Chien-Chin Hsu , Feng Liu

Depression is a severe mental disorder, and reliable identification plays a critical role in early intervention and treatment. Multimodal depression detection aims to improve diagnostic performance by jointly modeling complementary…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Chongxiao Wang , Junjie Liang , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Accurate and early diagnosis of Alzheimer's disease (AD) is critical for effective intervention and requires integrating complementary information from multimodal neuroimaging data. However, conventional fusion approaches often rely on…

Machine Learning · Computer Science 2026-04-14 Farica Zhuang , Shu Yang , Dinara Aliyeva , Zixuan Wen , Duy Duong-Tran , Christos Davatzikos , Tianlong Chen , Song Wang , Li Shen

Accelerated multi-modal magnetic resonance (MR) imaging is a new and effective solution for fast MR imaging, providing superior performance in restoring the target modality from its undersampled counterpart with guidance from an auxiliary…

Image and Video Processing · Electrical Eng. & Systems 2022-05-12 Chun-Mei Feng , Yunlu Yan , Geng Chen , Yong Xu , Ling Shao , Huazhu Fu

The integration of different imaging modalities, such as structural, diffusion tensor, and functional magnetic resonance imaging, with deep learning models has yielded promising outcomes in discerning phenotypic characteristics and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Zhiyuan Li , Hailong Li , Anca L. Ralescu , Jonathan R. Dillman , Mekibib Altaye , Kim M. Cecil , Nehal A. Parikh , Lili He

Multi-modality imaging is widely used in clinical practice and biomedical research to gain a comprehensive understanding of an imaging subject. Currently, multi-modality imaging is accomplished by post hoc fusion of independently…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Lingting Zhu , Yizheng Chen , Lianli Liu , Lei Xing , Lequan Yu

Depression is a leading cause of death worldwide, and the diagnosis of depression is nontrivial. Multimodal learning is a popular solution for automatic diagnosis of depression, and the existing works suffer two main drawbacks: 1) the…

Multimedia · Computer Science 2023-01-03 Chengbo Yuan , Qianhui Xu , Yong Luo

The integration of multimodal medical imaging can provide complementary and comprehensive information for the diagnosis of Alzheimer's disease (AD). However, in clinical practice, since positron emission tomography (PET) is often missing,…

Computational Engineering, Finance, and Science · Computer Science 2024-12-03 Fuyou Mao , Lixin Lin , Ming Jiang , Dong Dai , Chao Yang , Hao Zhang , Yan Tang

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Multimodal MRIs play a crucial role in clinical diagnosis and treatment. Feature disentanglement (FD)-based methods, aiming at learning superior feature representations for multimodal data analysis, have achieved significant success in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Tianling Liu , Hongying Liu , Fanhua Shang , Lequan Yu , Tong Han , Liang Wan

Multimodal neuroimage can provide complementary information about the dementia, but small size of complete multimodal data limits the ability in representation learning. Moreover, the data distribution inconsistency from different…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Qiankun Zuo , Baiying Lei , Yanyan Shen , Yong Liu , Zhiguang Feng , Shuqiang Wang

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Weichen Huang

Diagnosing dementia, particularly for Alzheimer's Disease (AD) and frontotemporal dementia (FTD), is complex due to overlapping symptoms. While magnetic resonance imaging (MRI) and positron emission tomography (PET) data are critical for…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Yitong Li , Morteza Ghahremani , Youssef Wally , Christian Wachinger

In this study, we focus on automated approaches to detect depression from clinical interviews using multi-modal machine learning (ML). Our approach differentiates from other successful ML methods such as context-aware analysis through…

Machine Learning · Computer Science 2024-12-30 Genevieve Lam , Huang Dongyan , Weisi Lin

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen

Multimodal deep learning methods capture synergistic features from multiple modalities and have the potential to improve accuracy for stress detection compared to unimodal methods. However, this accuracy gain typically comes from high…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Morteza Bodaghi , Majid Hosseini , Raju Gottumukkala