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Electronic health record (EHR) question answering is often handled by LLM-based pipelines that are costly to deploy and do not explicitly leverage the hierarchical structure of clinical data. Motivated by evidence that medical ontologies…

Artificial Intelligence · Computer Science 2026-04-24 Yuyu Liu , Sarang Rajendra Patil , Mengjia Xu , Tengfei Ma

Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Timothy A. Miller , Yanjun Gao , Matthew M. Churpek , Anoop Mayampurath , Dmitriy Dligach , Majid Afshar

Hyperbolic geometry has emerged as an effective latent space for representing complex networks, owing to its ability to capture hierarchical organization and heterogeneous connectivity patterns using low-dimensional embeddings. As a result,…

Machine Learning · Computer Science 2026-05-01 Sofía Pérez Casulo , Marcelo Fiori , Bernardo Marenco , Federico Larroca

The arrangement of network nodes in hyperbolic spaces has become a widely studied problem, motivated by numerous results suggesting the existence of hidden metric spaces behind the structure of complex networks. Although several methods…

Physics and Society · Physics 2023-02-06 Bianka Kovács , Gergely Palla

Finding suitable embeddings for connectomes (spatially embedded complex networks that map neural connections in the brain) is crucial for analyzing and understanding cognitive processes. Recent studies have found two-dimensional hyperbolic…

Neurons and Cognition · Quantitative Biology 2024-07-24 Dorota Celińska-Kopczyńska , Eryk Kopczyński

Hyperbolic representation learning has been widely used to extract implicit hierarchies within data, and recently it has found its way to the open-world classification task of Generalized Category Discovery (GCD). However, prior hyperbolic…

Machine Learning · Computer Science 2026-02-06 Mohamad Dalal , Thomas B. Moeslund , Joakim Bruslund Haurum

Large Language Models (LLMs) have attracted significant attention in recommender systems for their excellent world knowledge capabilities. However, existing methods that rely on Euclidean space struggle to capture the rich hierarchical…

Information Retrieval · Computer Science 2025-04-22 Wentao Cheng , Zhida Qin , Zexue Wu , Pengzhan Zhou , Tianyu Huang

Learning graph representations via low-dimensional embeddings that preserve relevant network properties is an important class of problems in machine learning. We here present a novel method to embed directed acyclic graphs. Following prior…

Machine Learning · Computer Science 2018-06-08 Octavian-Eugen Ganea , Gary Bécigneul , Thomas Hofmann

With powerful and integrative large language models (LLMs), medical AI agents have demonstrated unique advantages in providing personalized medical consultations, continuous health monitoring, and precise treatment plans.…

Hardware Architecture · Computer Science 2025-11-03 Zhipeng Liao , Kunming Shao , Jiangnan Yu , Liang Zhao , Tim Kwang-Ting Cheng , Chi-Ying Tsui , Jie Yang , Mohamad Sawan

With the daily influx of 3D data on the internet, text-3D retrieval has gained increasing attention. However, current methods face two major challenges: Hierarchy Representation Collapse (HRC) and Redundancy-Induced Saliency Dilution…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Wenrui Li , Yidan Lu , Yeyu Chai , Rui Zhao , Hengyu Man , Xiaopeng Fan

Many complex systems involve interactions between more than two agents. Hypergraphs capture these higher-order interactions through hyperedges that may link more than two nodes. We consider the problem of embedding a hypergraph into…

Social and Information Networks · Computer Science 2023-01-06 Xue Gong , Desmond J. Higham , Konstantinos Zygalakis

Graph representation learning in Euclidean space, despite its widespread adoption and proven utility in many domains, often struggles to effectively capture the inherent hierarchical and complex relational structures prevalent in real-world…

Machine Learning · Computer Science 2025-08-26 Menglin Yang , Min Zhou , Tong Zhang , Jiahong Liu , Zhihao Li , Lujia Pan , Hui Xiong , Irwin King

Multimodal learning that integrates histopathology images and genomic data holds great promise for cancer survival prediction. However, existing methods face key limitations: 1) They rely on multimodal mapping and metrics in Euclidean…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Jiaqi Yang , Wenting Chen , Xiaohan Xing , Sean He , Xiaoling Luo , Xinheng Lyu , Linlin Shen , Guoping Qiu

Large language models (LLMs) have shown great success in text modeling tasks across domains. However, natural language exhibits inherent semantic hierarchies and nuanced geometric structure, which current LLMs do not capture completely…

Machine Learning · Computer Science 2025-11-07 Neil He , Rishabh Anand , Hiren Madhu , Ali Maatouk , Smita Krishnaswamy , Leandros Tassiulas , Menglin Yang , Rex Ying

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Concept Bottleneck Models (CBMs) have become a popular approach to enable interpretability in neural networks by constraining classifier inputs to a set of human-understandable concepts. While effective, current models embed concepts in…

Machine Learning · Computer Science 2026-05-13 Daniel Uyterlinde , Swasti Shreya Mishra , Pascal Mettes

SNOMED CT is a biomedical ontology with a hierarchical representation, modelling terminological concepts at a large scale. Knowledge retrieval in SNOMED CT is critical for its application but often proves challenging due to linguistic…

Computation and Language · Computer Science 2026-04-21 Jonathon Dilworth , Hui Yang , Jiaoyan Chen , Yongsheng Gao , Ernesto Jimenez-Ruiz

With the recent advance of geometric deep learning, neural networks have been extensively used for data in non-Euclidean domains. In particular, hyperbolic neural networks have proved successful in processing hierarchical information of…

Machine Learning · Computer Science 2023-01-24 Eric Qu , Dongmian Zou

Foundation models pre-trained on massive datasets, including large language models (LLMs), vision-language models (VLMs), and large multimodal models, have demonstrated remarkable success in diverse downstream tasks. However, recent studies…

Machine Learning · Computer Science 2025-07-25 Neil He , Hiren Madhu , Ngoc Bui , Menglin Yang , Rex Ying

Representing data in hyperbolic space can effectively capture latent hierarchical relationships. With the goal of enabling accurate classification of points in hyperbolic space while respecting their hyperbolic geometry, we introduce…

Machine Learning · Computer Science 2018-06-04 Hyunghoon Cho , Benjamin DeMeo , Jian Peng , Bonnie Berger