English
Related papers

Related papers: Nobody Puts Bonferroni in a Corner

200 papers

What proportion of treated units actually benefited from an experimental intervention? What is the median or the largest individual treatment effect? This paper develops methods for answering such questions about the distribution of…

Methodology · Statistics 2026-05-11 David Kim , Yongchang Su , Jake Bowers , Xinran Li

Structured multiple-testing problems (gatekeeping trials, dose-finding, multi-tissue eQTL mapping, bundled-challenger A/B experiments) organize hypotheses into design-imposed blocks and demand strong family-wise error rate (FWER) control…

Methodology · Statistics 2026-05-28 Prasanjit Dubey , Xiaoming Huo

This paper tackles the challenge of performing multiple quantile regressions across different quantile levels and the associated problem of controlling the familywise error rate, an issue that is generally overlooked in practice. We propose…

Methodology · Statistics 2026-04-10 Riccardo De Santis , Anna Vesely , Angela Andreella

Online controlled experiments, such as A/B-tests, are commonly used by modern tech companies to enable continuous system improvements. Despite their paramount importance, A/B-tests are expensive: by their very definition, a percentage of…

Machine Learning · Computer Science 2024-01-09 Shubham Baweja , Neeti Pokharna , Aleksei Ustimenko , Olivier Jeunen

Inspired by online learning, data-dependent regret has recently been proposed as a criterion for controller design. In the regret-optimal control paradigm, causal controllers are designed to minimize regret against a hypothetical optimal…

Optimization and Control · Mathematics 2022-09-15 Gautam Goel , Babak Hassibi

Online controlled experiments are a crucial tool to allow for confident decision-making in technology companies. A North Star metric is defined (such as long-term revenue or user retention), and system variants that statistically…

Machine Learning · Computer Science 2024-06-14 Olivier Jeunen , Aleksei Ustimenko

Many online experiments exhibit dependence between users and items. For example, in online advertising, observations that have a user or an ad in common are likely to be associated. Because of this, even in experiments involving millions of…

Methodology · Statistics 2017-10-26 Eytan Bakshy , Dean Eckles

Results on the false discovery rate (FDR) and the false nondiscovery rate (FNR) are developed for single-step multiple testing procedures. In addition to verifying desirable properties of FDR and FNR as measures of error rates, these…

Statistics Theory · Mathematics 2007-06-13 Sanat K. Sarkar

Two-sample network hypothesis testing is an important inference task with applications across diverse fields such as medicine, neuroscience, and sociology. Many of these testing methodologies operate under the implicit assumption that the…

Methodology · Statistics 2024-05-28 Ayushi Saxena , Vince Lyzinski

Efron's two-group model is widely used in large scale multiple testing. This model assumes that test statistics are mutually independent, however in realistic settings they are typically dependent, and taking the dependence into account can…

Methodology · Statistics 2022-12-20 Rajesh Karmakar , Ruth Heller , Saharon Rosset

Recent results concerning asymptotic Bayes-optimality under sparsity (ABOS) of multiple testing procedures are extended to fairly generally distributed effect sizes under the alternative. An asymptotic framework is considered where both the…

Statistics Theory · Mathematics 2011-07-13 Florian Frommlet , Arijit Chakrabarti , Magdalena Murawska , Malgorzata Bogdan

Businesses frequently run online controlled experiments (i.e., A/B tests) to learn about the effect of an intervention on multiple business metrics. To account for multiple hypothesis testing, multiple metrics are commonly aggregated into a…

Methodology · Statistics 2026-01-22 Luke Hagar , Nathaniel T. Stevens

Background Most methods of adjusting for multiplicity focus primarily on controlling type I errors and rarely consider type II errors. We propose a new method that considers controlling for false-positive findings while ensuring sufficient…

Applications · Statistics 2025-07-31 Jiale Li , Zimu Wei

Online testing procedures assume that hypotheses are observed in sequence, and allow the significance thresholds for upcoming tests to depend on the test statistics observed so far. Some of the most popular online methods include alpha…

Methodology · Statistics 2022-02-11 Aaron Fisher

Lean is increasingly used to judge natural-language mathematical answers, but its signal is partial: many answers never formalize, and a failed proof may reflect an ill-typed statement or a missing library fact, not a wrong answer. On…

Artificial Intelligence · Computer Science 2026-05-28 Pauline Bourigault , Xiaotong Ji , Matthieu Zimmer , Rasul Tutunov , Haitham Bou Ammar

Testing multiple hypotheses of conditional independence with provable error rate control is a fundamental problem with various applications. To infer conditional independence with family-wise error rate (FWER) control when only summary…

Methodology · Statistics 2023-10-17 Catherine Xinrui Yu , Jiaqi Gu , Zhaomeng Chen , Zihuai He

After initial release of a machine learning algorithm, the model can be fine-tuned by retraining on subsequently gathered data, adding newly discovered features, or more. Each modification introduces a risk of deteriorating performance and…

Machine Learning · Statistics 2022-03-23 Jean Feng , Gene Pennello , Nicholas Petrick , Berkman Sahiner , Romain Pirracchio , Alexej Gossmann

We propose a simple single-step multiple testing procedure that asymptotically controls the family-wise error rate (FWER) at the desired level exactly under the equicorrelated multivariate Gaussian setup. The method is shown to be…

Statistics Theory · Mathematics 2025-08-14 Swarnadeep Datta , Monitirtha Dey

Multiple hypothesis testing, a situation when we wish to consider many hypotheses, is a core problem in statistical inference that arises in almost every scientific field. In this setting, controlling the false discovery rate (FDR), which…

Statistics Theory · Mathematics 2019-03-19 Shiyun Chen , Shiva Kasiviswanathan

Consider the problem of testing multiple null hypotheses. A classical approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate ($FWER$), the probability of even one…

Statistics Theory · Mathematics 2007-06-13 Joseph P. Romano , Azeem M. Shaikh