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Multi-modality medical imaging is crucial in clinical treatment as it can provide complementary information for medical image segmentation. However, collecting multi-modal data in clinical is difficult due to the limitation of the scan time…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Shuai Wang , Zipei Yan , Daoan Zhang , Haining Wei , Zhongsen Li , Rui Li

Microscopy-based phenotypic profiling is scalable for drug discovery but lacks the mechanistic depth of transcriptomics, which remains costly and scarce. Existing multimodal approaches either use images to support other modalities or…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Jiayuan Chen , Ruoqi Liu , Zishan Gu , Ping Zhang

Spatial transcriptomics (ST) provides crucial insights into tissue micro-environments, but is limited to its high cost and complexity. As an alternative, predicting gene expression from pathology whole slide images (WSI) is gaining…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mingcheng Qu , Yuncong Wu , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Pathological diagnosis relies on the visual inspection of histologically stained thin tissue specimens, where different types of stains are applied to bring contrast to and highlight various desired histological features. However, the…

Medical Physics · Physics 2022-08-18 Xilin Yang , Bijie Bai , Yijie Zhang , Yuzhu Li , Kevin de Haan , Tairan Liu , Aydogan Ozcan

Histopathological analysis has been transformed by serial section-based methods, advancing beyond traditional 2D histology to enable volumetric and microstructural insights in oncology and inflammatory disease diagnostics. This review…

Tissues and Organs · Quantitative Biology 2025-08-05 Zhenfeng Zhuang , Min Cen , Lei Jiang , Qiong Peng , Yihuang Hu , Hong-Yu Zhou , Liansheng Wang

Cross-modal medical image segmentation presents a significant challenge, as different imaging modalities produce images with varying resolutions, contrasts, and appearances of anatomical structures. We introduce compositionality as an…

Computer Vision and Pattern Recognition · Computer Science 2024-08-22 Aniek Eijpe , Valentina Corbetta , Kalina Chupetlovska , Regina Beets-Tan , Wilson Silva

Improving the performance of semantic segmentation models using multispectral information is crucial, especially for environments with low-light and adverse conditions. Multi-modal fusion techniques pursue either the learning of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Aniruddh Sikdar , Jayant Teotia , Suresh Sundaram

Scene information plays a crucial role in trajectory forecasting systems for autonomous driving by providing semantic clues and constraints on potential future paths of traffic agents. Prevalent trajectory prediction techniques often take…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Yuning Wang , Pu Zhang , Lei Bai , Jianru Xue

Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…

Methodology · Statistics 2022-09-15 Andrea Sottosanti , Davide Risso

Deploying language models often requires navigating accuracy vs. performance trade-offs to meet latency constraints while preserving utility. Traditional model distillation reduces size but incurs substantial costs through training separate…

Computation and Language · Computer Science 2026-01-27 Andrea Gurioli , Federico Pennino , João Monteiro , Maurizio Gabbrielli

Spatial transcriptomics clustering is pivotal for identifying cell subpopulations by leveraging spatial location information. While recent graph-based methods modeling cell-cell interactions have improved clustering accuracy, they remain…

Machine Learning · Computer Science 2026-01-21 Chenkai Guo , Yikai Zhu , Renxiang Guan , Jinli Ma , Siwei Wang , Ke Liang , Guangdun Peng , Dayu Hu

Knowledge distillation (KD) has proven highly effective for compressing large models and enhancing the performance of smaller ones. However, its effectiveness diminishes in cross-modal scenarios, such as vision-to-language distillation,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Junhong Liu , Yuan Zhang , Tao Huang , Wenchao Xu , Renyu Yang

Learning based on multimodal data has attracted increasing interest recently. While a variety of sensory modalities can be collected for training, not all of them are always available in development scenarios, which raises the challenge to…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Shicai Wei , Yang Luo , Chunbo Luo

U-Nets have achieved tremendous success in medical image segmentation. Nevertheless, it may suffer limitations in global (long-range) contextual interactions and edge-detail preservation. In contrast, Transformer has an excellent ability to…

Computer Vision and Pattern Recognition · Computer Science 2022-06-03 Nan Wang , Shaohui Lin , Xiaoxiao Li , Ke Li , Yunhang Shen , Yue Gao , Lizhuang Ma

The development of computer vision solutions for gigapixel images in digital pathology is hampered by significant computational limitations due to the large size of whole slide images. In particular, digitizing biopsies at high resolutions…

Computer Vision and Pattern Recognition · Computer Science 2024-01-12 Rocío del Amor , Julio Silva-Rodríguez , Adrián Colomer , Valery Naranjo

Spatial Transcriptomics (ST) enables the measurement of gene expression while preserving spatial information, offering critical insights into tissue architecture and disease pathology. Recent developments have explored the use of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Hai Dang Nguyen , Nguyen Dang Huy Pham , The Minh Duc Nguyen , Dac Thai Nguyen , Hang Thi Nguyen , Duong M. Nguyen

Multi-modal recommendation has gained traction as items possess rich attributes like text and images. Semantic ID-based approaches effectively discretize this information into compact tokens. However, two challenges persist: (1) Suboptimal…

Artificial Intelligence · Computer Science 2026-05-27 Pingjun Pan , Tingting Zhou , Peiyao Lu , Tingting Fei , Hongxiang Chen , Chuanjiang Luo

Monocular 3D object detection is a promising yet ill-posed task for autonomous vehicles due to the lack of accurate depth information. Cross-modality knowledge distillation could effectively transfer depth information from LiDAR to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Rui Ding , Meng Yang , Nanning Zheng

Convolutional neural networks (CNNs) are a standard tool for computer vision tasks such as image classification. However, typical model architectures may result in the loss of topological information. In specific domains such as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-05 Shrunal Pothagoni , Benjamin Schweinhart

The success of automated medical image analysis depends on large-scale and expert-annotated training sets. Unsupervised domain adaptation (UDA) has been raised as a promising approach to alleviate the burden of labeled data collection.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Jianan Fan , Dongnan Liu , Hang Chang , Heng Huang , Mei Chen , Weidong Cai
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