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Ophthalmic diseases pose a significant global health burden. However, traditional diagnostic methods and existing monocular image-based deep learning approaches often overlook the pathological correlations between the two eyes. In practical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Guohao Huo , Zibo Lin , Zitong Wang , Ruiting Dai , Hao Tang

Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 S. Chen , D. Ma , M. Raviselvan , S. Sundaramoorthy , K. Popuri , M. J. Ju , M. V. Sarunic , D. Ratra , M. F. Beg

In this paper, an optic disc and cup segmentation method is proposed using U-Net followed by a multi-scale feature matching network. The proposed method targets task 2 of the REFUGE challenge 2018. In order to solve the segmentation problem…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Vivek Kumar Singh , Hatem A. Rashwan , Adel Saleh , Farhan Akram , Md Mostafa Kamal Sarker , Nidhi Pandey , Saddam Abdulwahab

The optic disc segmentation is an important step for retinal image-based disease diagnosis such as glaucoma. The inner limiting membrane (ILM) is the first boundary in the OCT, which can help to extract the retinal pigment epithelium (RPE)…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Hao Qiu , Zaiwang Gu , Lei Mou , Xiaoqian Mao , Liyang Fang , Yitian Zhao , Jiang Liu , Jun Cheng

Accurate isolation and quantification of intraocular dimensions in the anterior segment (AS) of the eye using optical coherence tomography (OCT) images is important in the diagnosis and treatment of many eye diseases, especially angle…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Tan Hung Pham , Sripad Krishna Devalla , Aloysius Ang , Soh Zhi Da , Alexandre H. Thiery , Craig Boote , Ching-Yu Cheng , Victor Koh , Michael J. A. Girard

Nasopharyngeal carcinoma (NPC) is a kind of malignant tumor. Accurate and automatic segmentation of organs at risk (OAR) of computed tomography (CT) images is clinically significant. In recent years, deep learning models represented by…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Zexi Huang , Lihua Guo , Xin Yang , Sijuan Huang

Optic nerve head (ONH) detection has been a crucial area of study in ophthalmology for years. However, the significant discrepancy between fundus image datasets, each generated using a single type of fundus camera, poses challenges to the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Jiayi Wang , Yi-An Mao , Xiaoyu Ma , Sicen Guo , Yuting Shao , Xiao Lv , Wenting Han , Mark Christopher , Linda M. Zangwill , Yanlong Bi , Rui Fan

Purpose: To evaluate nerve fiber layer (NFL) reflectance for glaucoma diagnosis. Methods: Participants were imaged with 4.5X4.5-mm volumetric disc scans using spectral-domain optical coherence tomography (OCT). The normalized NFL…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ou Tan , Liang Liu , Qisheng You , Jie Wang , Aiyin Chen , Eliesa Ing , John C. Morrison , Yali Jia , David Huang

Despite significant advancements, segmentation based on deep neural networks in medical and surgical imaging faces several challenges, two of which we aim to address in this work. First, acquiring complete pixel-level segmentation labels…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Junwen Wang , Zhonghao Wang , Oscar MacCormac , Jonathan Shapey , Tom Vercauteren

Objective: The spinous process angle (SPA) is one of the essential parameters to denote three-dimensional (3-D) deformity of spine. We propose an automatic segmentation method based on Stacked Hourglass Network (SHN) to detect the spinous…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Hong-Ye Zeng , Song-Han Ge , Yu-Chong Gao , De-Sen Zhou , Kang Zhou , Xu-Ming He , Edmond Lou , Rui Zheng

Purpose: (1) To assess the performance of geometric deep learning (PointNet) in diagnosing glaucoma from a single optical coherence tomography (OCT) 3D scan of the optic nerve head (ONH); (2) To compare its performance to that obtained with…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Alexandre H. Thiery , Fabian Braeu , Tin A. Tun , Tin Aung , Michael J. A. Girard

This work explores a hybrid approach to segmentation as an alternative to a purely data-driven approach. We introduce an end-to-end U-Net based network called DU-Net, which uses additional frequency preserving features, namely the…

Image and Video Processing · Electrical Eng. & Systems 2020-04-16 Alakh Desai , Ruchi Chauhan , Jayanthi Sivaswamy

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

To develop a new method to quantify nonperfused retinal capillaries (NPCs) by using co-registered optical coherence tomography (OCT) and OCT angiography (OCTA), and to evaluate NPCs in eyes with age-related macular degeneration (AMD) and…

Quantitative Methods · Quantitative Biology 2024-11-11 Min Gao , Yukun Guo , Tristan T. Hormel , Jie Wang , Elizabeth White , Dong-Wouk Park , Thomas S. Hwang , Steven T. Bailey , Yali Jia

Nasopharyngeal Carcinoma (NPC) is a leading form of Head-and-Neck (HAN) cancer in the Arctic, China, Southeast Asia, and the Middle East/North Africa. Accurate segmentation of Organs-at-Risk (OAR) from Computed Tomography (CT) images with…

Image and Video Processing · Electrical Eng. & Systems 2021-02-04 Wenhui Lei , Haochen Mei , Zhengwentai Sun , Shan Ye , Ran Gu , Huan Wang , Rui Huang , Shichuan Zhang , Shaoting Zhang , Guotai Wang

Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy,…

The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Abhay Shah , Michael Abramoff , Xiaodong Wu

Objective: To validate and compare the performance of eight available deep learning architectures in grading the severity of glaucoma based on color fundus images. Materials and Methods: We retrospectively collected a dataset of 5978 fundus…

Computer Vision and Pattern Recognition · Computer Science 2018-11-01 Yi Zhen , Lei Wang , Han Liu , Jian Zhang , Jiantao Pu

Existing studies tend tofocus onmodel modifications and integration with higher accuracy, which improve performance but also carry huge computational costs, resulting in longer detection times. Inmedical imaging, the use of time is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-22 Weihu Song , Heng Yu

Retinal vessel segmentation is crucial for diagnosis and assessment of ocular diseases. Notably, segmentation of small retinal vessels has been consistently recognized as a challenging and complex task. To tackle this challenge, we design a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yuanyuan Peng , Wen Li
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