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Large language models (LLMs) have shown promising capabilities in healthcare analysis but face several challenges like hallucinations, parroting, and bias manifestation. These challenges are exacerbated in complex, sensitive, and…

Computation and Language · Computer Science 2024-12-18 Vivek Kumar , Eirini Ntoutsi , Pushpraj Singh Rajawat , Giacomo Medda , Diego Reforgiato Recupero

Synthetic data has gained significant momentum thanks to sophisticated machine learning tools that enable the synthesis of high-dimensional datasets. However, many generation techniques do not give the data controller control over what…

Cryptography and Security · Computer Science 2022-11-22 Florimond Houssiau , Samuel N. Cohen , Lukasz Szpruch , Owen Daniel , Michaela G. Lawrence , Robin Mitra , Henry Wilde , Callum Mole

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. Modern approaches for data generation based on machine…

Machine Learning · Computer Science 2023-01-11 Chao Yan , Yao Yan , Zhiyu Wan , Ziqi Zhang , Larsson Omberg , Justin Guinney , Sean D. Mooney , Bradley A. Malin

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

Artificial Intelligence · Computer Science 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani

The development of medical chatbots in Arabic is significantly constrained by the scarcity of large-scale, high-quality annotated datasets. While prior efforts compiled a dataset of 20,000 Arabic patient-doctor interactions from social…

Computation and Language · Computer Science 2025-09-15 Abdulrahman Allam , Seif Ahmed , Ali Hamdi , Khaled Shaban

Commonsense reasoning is a critical aspect of human communication. Despite recent advances in conversational AI driven by large language models, commonsense reasoning remains a challenging task. In this work, we introduce SYNDICOM - a…

Computation and Language · Computer Science 2023-09-20 Christopher Richardson , Anirudh Sundar , Larry Heck

This paper explores SynTOD, a new synthetic data generation approach for developing end-to-end Task-Oriented Dialogue (TOD) Systems capable of handling complex tasks such as intent classification, slot filling, conversational…

Computation and Language · Computer Science 2024-04-24 Chris Samarinas , Pracha Promthaw , Atharva Nijasure , Hansi Zeng , Julian Killingback , Hamed Zamani

Navigating health questions can be daunting in the modern information landscape. Large language models (LLMs) may provide tailored, accessible information, but also risk being inaccurate, biased or misleading. We present insights from 4…

Diagnostic errors in healthcare persist as a critical challenge, with increasing numbers of patients turning to online resources for health information. While AI-powered healthcare chatbots show promise, there exists no standardized and…

Artificial Intelligence · Computer Science 2024-12-18 Deep Bhatt , Surya Ayyagari , Anuruddh Mishra

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

The development of conversational agents to interact with patients and deliver clinical advice has attracted the interest of many researchers, particularly in light of the COVID-19 pandemic. The training of an end-to-end neural based dialog…

Computation and Language · Computer Science 2022-12-13 Deeksha Varshney , Aizan Zafar , Niranshu Kumar Behra , Asif Ekbal

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Creating effective dialogue systems for mental health support requires high-quality multi-turn counseling dialogue data, yet collecting real counselor-client conversations presents significant challenges, including privacy concerns, high…

Computation and Language · Computer Science 2026-05-27 Huachuan Qiu , Zhenzhong Lan

Medical dialogue systems have attracted growing research attention as they have the potential to provide rapid diagnoses, treatment plans, and health consultations. In medical dialogues, a proper diagnosis is crucial as it establishes the…

Computation and Language · Computer Science 2024-01-15 Kaishuai Xu , Wenjun Hou , Yi Cheng , Jian Wang , Wenjie Li

Therapeutic dialogue is not a sequence of isolated responses: client goals, motivation, resistance, and therapeutic alliance evolve over time. Yet current LLM-based mental health dialogue systems often lack explicit mechanisms for tracking…

The diagnosis of oral diseases presents a problematic clinical challenge, characterized by a wide spectrum of pathologies with overlapping symptomatology. To address this, we developed Clinical Semantic Intelligence (CSI), a novel…

Artificial Intelligence · Computer Science 2025-07-22 Mohammad Mashayekhi , Sara Ahmadi Majd , Arian AmirAmjadi , Parsa Hosseini

Clinical dialogue represents a complex duality requiring both the empathetic fluency of natural conversation and the rigorous precision of evidence-based medicine. While Large Language Models possess unprecedented linguistic capabilities,…

Other Quantitative Biology · Quantitative Biology 2025-12-02 Xiaoquan Zhi , Hongke Zhao , Likang Wu , Chuang Zhao , Hengshu Zhu

Research involving privacy-sensitive data has always been constrained by data scarcity, standing in sharp contrast to other areas that have benefited from data scaling. This challenge is becoming increasingly urgent as modern AI…

Serious illness communication (SIC) in end-of-life care faces challenges such as emotional stress, cultural barriers, and balancing hope with honesty. Despite its importance, one of the few available ways for clinicians to practice SIC is…

Human-Computer Interaction · Computer Science 2025-05-06 Kurtis Haut , Masum Hasan , Thomas Carroll , Ronald Epstein , Taylan Sen , Ehsan Hoque