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Finding small lesions is very challenging due to lack of noticeable features, severe class imbalance, as well as the size itself. One approach to improve small lesion segmentation is to reduce the region of interest and inspect it at a…

Image and Video Processing · Electrical Eng. & Systems 2022-08-01 Seung Yeon Shin , Thomas C. Shen , Stephen A. Wank , Ronald M. Summers

Accurate grading of Conjunctival Melanocytic Intraepithelial Lesions (CMIL) is essential for treatment and melanoma prediction but remains difficult due to subtle morphological cues and interrelated diagnostic criteria. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Mert Ikinci , Luna Toma , Karin U. Loeffler , Leticia Ussem , Daniela Süsskind , Julia M. Weller , Yousef Yeganeh , Martina C. Herwig-Carl , Shadi Albarqouni

Precisely locating and segmenting medical instruments in images of minimally invasive surgeries, medical instrument segmentation, is an essential first step for several tasks in medical image processing. However, image degradations, small…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Christian Wilms , Alexander Michael Gerlach , Rüdiger Schmitz , Simone Frintrop

Medical referring image segmentation (MRIS) requires pixel-level masks aligned with textual descriptions of anatomical locations, making annotation costly in low-label regimes. Semi-supervised learning (SSL) can mitigate this burden by…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yuchen Li , Zhen Zhao , Yi Liu , Luping Zhou

Brain lesions, including stroke and tumours, have a high degree of variability in terms of location, size, intensity and form, making automatic segmentation difficult. We propose an improvement to existing segmentation methods by exploiting…

Image and Video Processing · Electrical Eng. & Systems 2019-07-22 Kevin Raina , Uladzimir Yahorau , Tanya Schmah

Deep neural networks have demonstrated exceptional efficacy in stroke lesion segmentation. However, the delineation of small lesions, critical for stroke diagnosis, remains a challenge. In this study, we propose two straightforward yet…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Liang Shang , Zhengyang Lou , Andrew L. Alexander , Vivek Prabhakaran , William A. Sethares , Veena A. Nair , Nagesh Adluru

In clinical practice, segmenting specific lesions based on the needs of physicians can significantly enhance diagnostic accuracy and treatment efficiency. However, conventional lesion segmentation models lack the flexibility to distinguish…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shuyi Ouyang , Jinyang Zhang , Xiangye Lin , Xilai Wang , Qingqing Chen , Yen-Wei Chen , Lanfen Lin

Semi-supervised learning for medical image segmentation is an important area of research for alleviating the huge cost associated with the construction of reliable large-scale annotations in the medical domain. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Chae Eun Lee , Hyelim Park , Yeong-Gil Shin , Minyoung Chung

Medical image segmentation plays a vital role in various clinical applications, enabling accurate delineation and analysis of anatomical structures or pathological regions. Traditional CNNs have achieved remarkable success in this field.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Large language models (LLMs) have shown promising capabilities in visually interpreting medical time-series data. However, their general-purpose design can limit domain-specific precision, and the proprietary nature of many models poses…

Artificial Intelligence · Computer Science 2025-07-22 Huayu Li , Zhengxiao He , Xiwen Chen , Ci Zhang , Stuart F. Quan , William D. S. Killgore , Shu-Fen Wung , Chen X. Chen , Geng Yuan , Jin Lu , Ao Li

Medical image segmentation has witnessed significant advancements with the emergence of deep learning. However, the reliance of most neural network models on a substantial amount of annotated data remains a challenge for medical image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Xiaoxiao Wu , Xiaowei Chen , Zhenguo Gao , Shulei Qu , Yuanyuan Qiu

Traditional loss functions in medical image segmentation, such as Dice, often under-segment small lesions because their small relative volume contributes negligibly to the overall loss. To address this, instance-wise loss functions and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Luc Bouteille , Alexander Jaus , Jens Kleesiek , Rainer Stiefelhagen , Lukas Heine

Partially-supervised learning can be challenging for segmentation due to the lack of supervision for unlabeled structures, and the methods directly applying fully-supervised learning could lead to incompatibility, meaning ground truth is…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Ke Zhang , Xiahai Zhuang

Leveraging multimodal information from Magnetic Resonance Imaging (MRI) plays a vital role in lesion segmentation, especially for brain tumors. However, in clinical practice, multimodal MRI data are often incomplete, making it challenging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Yulong Zou , Bo Liu , Cun-Jing Zheng , Yuan-ming Geng , Siyue Li , Qiankun Zuo , Shuihua Wang , Yudong Zhang , Jin Hong

Accurate lesion segmentation in histopathology images is essential for diagnostic interpretation and quantitative analysis, yet it remains challenging due to the limited availability of costly pixel-level annotations. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Hangbei Cheng , Xiaorong Dong , Xueyu Liu , Jianan Zhang , Xuetao Ma , Mingqiang Wei , Liansheng Wang , Junxin Chen , Yongfei Wu

Medical image segmentation is more clinically valuable when it supports diagnosis rather than merely producing lesion masks. However, diagnostically relevant lesion cues are often subtle and localized, while existing models may be…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Fengyi Zhang , Xujie Zeng , Mohan Liu , Zengyi Wang , Yalong Jiang

The goal of self-supervised visual representation learning is to learn strong, transferable image representations, with the majority of research focusing on object or scene level. On the other hand, representation learning at part level has…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Subhabrata Choudhury , Iro Laina , Christian Rupprecht , Andrea Vedaldi

Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

Deep learning techniques have shown great potential in medical image processing, particularly through accurate and reliable image segmentation on magnetic resonance imaging (MRI) scans or computed tomography (CT) scans, which allow the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Yang Liu , Ersi Zhang , Lulu Xu , Chufan Xiao , Xiaoyun Zhong , Lijin Lian , Fang Li , Bin Jiang , Yuhan Dong , Lan Ma , Qiming Huang , Ming Xu , Yongbing Zhang , Dongmei Yu , Chenggang Yan , Peiwu Qin

Semi-supervised learning (SSL), which aims at leveraging a few labeled images and a large number of unlabeled images for network training, is beneficial for relieving the burden of data annotation in medical image segmentation. According to…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Xinkai Zhao , Chaowei Fang , De-Jun Fan , Xutao Lin , Feng Gao , Guanbin Li