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Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

We introduce InfiFusion, an efficient training pipeline designed to integrate multiple domain-specialized Large Language Models (LLMs) into a single pivot model, effectively harnessing the strengths of each source model. Traditional fusion…

Computation and Language · Computer Science 2025-02-18 Zhaoyi Yan , Yiming Zhang , Baoyi He , Yuhao Fu , Qi Zhou , Zhijie Sang , Chunlin Ji , Shengyu Zhang , Fei Wu , Hongxia Yang

Federated learning (FL) is a popular privacy-preserving paradigm that enables distributed clients to collaboratively train models with a central server while keeping raw data locally. In practice, distinct model architectures, varying data…

Machine Learning · Computer Science 2024-05-28 Yuting Ma , Lechao Cheng , Yaxiong Wang , Zhun Zhong , Xiaohua Xu , Meng Wang

Whole slide image (WSI) analysis has emerged as an increasingly essential technique in computational pathology. Recent advances in the pathology foundation models (FMs) have demonstrated significant advantages in deriving meaningful…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Zhidong Yang , Xiuhui Shi , Wei Ba , Zhigang Song , Haijing Luan , Taiyuan Hu , Senlin Lin , Jiguang Wang , Shaohua Kevin Zhou , Rui Yan

Large Language Models (LLMs) have demonstrated remarkable effectiveness in adapting to downstream tasks through fine-tuning. Federated Learning (FL) extends this capability by enabling collaborative fine-tuning across distributed clients…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-20 Zikai Zhang , Rui Hu , Jiahao Xu

Model merging aims to integrate multiple expert models into a single model that inherits their complementary strengths without incurring the inference-time cost of ensembling. Recent progress has shown that merging can be highly effective…

Artificial Intelligence · Computer Science 2026-05-19 Shilian Chen , Jie Zhou , Qin Chen , Wen Wu , Xin Li , Qi Feng , Liang He

Pathology foundation models (PFMs) have demonstrated strong representational capabilities through self-supervised pre-training on large-scale, unannotated histopathology image datasets. However, their diverse yet opaque pretraining…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yuxiang Xiao , Yang Hu , Bin Li , Tianyang Zhang , Zexi Li , Huazhu Fu , Jens Rittscher , Kaixiang Yang

Federated learning (FL) aims to collaboratively train a shared model across multiple clients without transmitting their local data. Data heterogeneity is a critical challenge in realistic FL settings, as it causes significant performance…

Machine Learning · Computer Science 2023-11-15 Yuwei Wang , Runhan Li , Hao Tan , Xuefeng Jiang , Sheng Sun , Min Liu , Bo Gao , Zhiyuan Wu

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

The rapid advancement of large language models (LLMs) has created a diverse landscape of models, each excelling at different tasks. This diversity drives researchers to employ multiple LLMs in practice, leaving behind valuable multi-LLM log…

Machine Learning · Computer Science 2025-09-30 Tao Feng , Haozhen Zhang , Zijie Lei , Pengrui Han , Mostofa Patwary , Mohammad Shoeybi , Bryan Catanzaro , Jiaxuan You

Differentiable simulation of soft bodies is a foundation for system identification, trajectory optimization, and Real2Sim transfer. Yet, existing methods such as the differentiable Projective Dynamics (DiffPD) struggle when faced with…

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Efficient fine-tuning of large language models for task-specific applications is imperative, yet the vast number of parameters in these models makes their training increasingly challenging. Despite numerous proposals for effective methods,…

Computation and Language · Computer Science 2024-10-15 Chenghao Fan , Zhenyi Lu , Wei Wei , Jie Tian , Xiaoye Qu , Dangyang Chen , Yu Cheng

Foundation models trained on large-scale pathology image corpora have demonstrated strong transfer capabilities across diverse histopathology tasks. Building on this progress, we introduce PLUTO-4, our next generation of pathology…

Heterogeneous model fusion enhances the performance of LLMs by integrating the knowledge and capabilities of multiple structurally diverse models. However, existing approaches often rely solely on selecting the best output for each prompt…

Computation and Language · Computer Science 2025-04-18 Longguang Zhong , Fanqi Wan , Ziyi Yang , Guosheng Liang , Tianyuan Shi , Xiaojun Quan

As FMs drive progress toward Artificial General Intelligence (AGI), fine-tuning them under privacy and resource constraints has become increasingly critical particularly when highquality training data resides on distributed edge devices.…

Machine Learning · Computer Science 2025-08-27 Gang Hu , Yinglei Teng , Pengfei Wu , Nan Wang

Edge intelligence has emerged as a promising strategy to deliver low-latency and ubiquitous services for mobile devices. Recent advances in fine-tuning mechanisms of foundation models have enabled edge intelligence by integrating low-rank…

Signal Processing · Electrical Eng. & Systems 2025-09-25 Jingyi Wang , Zhongyuan Zhao , Qingtian Wang , Zexu Li , Yue Wang , Tony Q. S. Quek

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Federated learning has received significant attention for its ability to simultaneously protect customer privacy and leverage distributed data from multiple devices for model training. However, conventional approaches often focus on…

Machine Learning · Computer Science 2025-10-07 Jiahao Zeng , Wolong Xing , Liangtao Shi , Xin Huang , Jialin Wang , Zhile Cao , Zhenkui Shi
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