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Identifying unique characteristics in a network through comparison with another network is an essential network analysis task. For example, with networks of protein interactions obtained from normal and cancer tissues, we can discover…

Machine Learning · Computer Science 2022-02-16 Takanori Fujiwara , Jian Zhao , Francine Chen , Yaoliang Yu , Kwan-Liu Ma

One-shot medical image segmentation (MIS) is crucial for medical analysis due to the burden of medical experts on manual annotation. The recent emergence of the segment anything model (SAM) has demonstrated remarkable adaptation in MIS but…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Jia Wang , Yunan Mei , Jiarui Liu , Xin Fan

The study of histopathological subtypes is valuable for the personalisation of effective treatment strategies for ovarian cancer. However, increasing diagnostic workloads present a challenge for UK pathology departments, leading to the rise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marcus Jenkins , Jasenka Mazibrada , Bogdan Leahu , Michal Mackiewicz

Data imbalance between common and rare diseases during model training often causes intelligent diagnosis systems to have biased predictions towards common diseases. The state-of-the-art approaches apply a two-stage learning framework to…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Chenghua Zeng , Huijuan Lu , Kanghao Chen , Ruixuan Wang , Wei-Shi Zheng

The effective management of brain tumors relies on precise typing, subtyping, and grading. This study advances patient care with findings from rigorous multiple instance learning experimentations across various feature extractors and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Ekansh Chauhan , Amit Sharma , Megha S Uppin , C. V. Jawahar , P. K. Vinod

Deep convolutional neural network (DCNN) models have been widely explored for skin disease diagnosis and some of them have achieved the diagnostic outcomes comparable or even superior to those of dermatologists. However, broad…

Computer Vision and Pattern Recognition · Computer Science 2022-02-14 Peng Yao , Shuwei Shen , Mengjuan Xu , Peng Liu , Fan Zhang , Jinyu Xing , Pengfei Shao , Benjamin Kaffenberger , Ronald X. Xu

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Accurate tumor detection in digital pathology whole-slide images (WSIs) is crucial for cancer diagnosis and treatment planning. Multiple Instance Learning (MIL) has emerged as a widely used approach for weakly-supervised tumor detection…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Marina D'Amato , Jeroen van der Laak , Francesco Ciompi

To date, the most common approach for radiology deep learning pipelines is the use of end-to-end 3D networks based on models pre-trained on other tasks, followed by fine-tuning on the task at hand. In contrast, adjacent medical fields such…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Marta Ligero , Tim Lenz , Georg Wölflein , Omar S. M. El Nahhas , Daniel Truhn , Jakob Nikolas Kather

Multiple instance learning (MIL) is the standard approach for whole-slide image (WSI) classification and survival prediction, where attention-based models ag gregate patch features into slide-level predictions. These models treat attention…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Xiangyu Li , Ran Su

Multiple instance learning (MIL) can reduce the need for costly annotation in tasks such as semantic segmentation by weakening the required degree of supervision. We propose a novel MIL formulation of multi-class semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2015-04-16 Deepak Pathak , Evan Shelhamer , Jonathan Long , Trevor Darrell

Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Jinqiu Chen , Huyan Xu

Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions,…

Class incremental learning (CIL) aims to recognize both the old and new classes along the increment tasks. Deep neural networks in CIL suffer from catastrophic forgetting and some approaches rely on saving exemplars from previous tasks,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Xiuwei Chen , Xiaobin Chang

Multiple Instance Learning (MIL) is increasingly being used as a support tool within clinical settings for pathological diagnosis decisions, achieving high performance and removing the annotation burden. However, existing approaches for…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Sungrae Hong , Kyungeun Kim , Juhyeon Kim , Sol Lee , Jisu Shin , Chanjae Song , Mun Yong Yi

Digitization of histology images and the advent of new computational methods, like deep learning, have helped the automatic grading of colorectal adenocarcinoma cancer (CRA). Present automated CRA grading methods, however, usually use tiny…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Neda Zamanitajeddin , Mostafa Jahanifar , Nasir Rajpoot

Deep neural networks have shown promising results in disease detection and classification using medical image data. However, they still suffer from the challenges of handling real-world scenarios especially reliably detecting…

Image and Video Processing · Electrical Eng. & Systems 2021-11-03 Muhammad Zaida , Shafaqat Ali , Mohsen Ali , Sarfaraz Hussein , Asma Saadia , Waqas Sultani

One-Class Classification (OCC) is a special case of multi-class classification, where data observed during training is from a single positive class. The goal of OCC is to learn a representation and/or a classifier that enables recognition…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Pramuditha Perera , Poojan Oza , Vishal M. Patel

Machine Learning (ML) approaches have been used to enhance the detection capabilities of Network Intrusion Detection Systems (NIDSs). Recent work has achieved near-perfect performance by following binary- and multi-class network anomaly…

Cryptography and Security · Computer Science 2022-12-16 Mohanad Sarhan , Gayan Kulatilleke , Wai Weng Lo , Siamak Layeghy , Marius Portmann

Regression via classification (RvC) is a common method used for regression problems in deep learning, where the target variable belongs to a set of continuous values. By discretizing the target into a set of non-overlapping classes, it has…

Machine Learning · Computer Science 2022-04-11 Axel Berg , Magnus Oskarsson , Mark O'Connor