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Retrieval Augmented Generation (RAG) is a promising technique for mitigating two key limitations of large language models (LLMs): outdated information and hallucinations. RAG system stores documents as embedding vectors in a database. Given…

Information Retrieval · Computer Science 2026-02-10 Taehee Jeong , Xingzhe Zhao , Peizu Li , Markus Valvur , Weihua Zhao

With appropriate data selection and training techniques, Large Language Models (LLMs) have demonstrated exceptional success in various medical examinations and multiple-choice questions. However, the application of LLMs in medical dialogue…

Computation and Language · Computer Science 2024-03-12 Jiageng Wu , Xian Wu , Yefeng Zheng , Jie Yang

Knowledge gaps and hallucinations are persistent challenges for Large Language Models (LLMs), which generate unreliable responses when lacking the necessary information to fulfill user instructions. Existing approaches, such as…

Computation and Language · Computer Science 2025-11-20 Riccardo Pozzi , Matteo Palmonari , Andrea Coletta , Luigi Bellomarini , Jens Lehmann , Sahar Vahdati

Large Language Models (LLMs) are pre-trained on large-scale corpora and excel in numerous general natural language processing (NLP) tasks, such as question answering (QA). Despite their advanced language capabilities, when it comes to…

Considering the inherent limitations of parametric knowledge in large language models (LLMs), retrieval-augmented generation (RAG) is widely employed to expand their knowledge scope. Since RAG has shown promise in knowledge-intensive tasks…

Computation and Language · Computer Science 2025-05-20 Yuhao Wang , Ruiyang Ren , Yucheng Wang , Wayne Xin Zhao , Jing Liu , Hua Wu , Haifeng Wang

Large Language Models (LLMs) have exhibited impressive generation capabilities, but they suffer from hallucinations when solely relying on their internal knowledge, especially when answering questions that require less commonly known…

Computation and Language · Computer Science 2023-11-01 Wenting Zhao , Ye Liu , Tong Niu , Yao Wan , Philip S. Yu , Shafiq Joty , Yingbo Zhou , Semih Yavuz

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Large Language Models (LLMs) have exhibited remarkable capabilities in clinical scenarios. Despite their potential, existing works face challenges when applying LLMs to medical settings. Strategies relying on training with medical datasets…

Computation and Language · Computer Science 2025-10-10 Keer Lu , Zheng Liang , Da Pan , Shusen Zhang , Guosheng Dong , Zhonghai Wu , Huang Leng , Bin Cui , Wentao Zhang

While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu

Knowledge Tracing (KT) models students' evolving knowledge states to predict future performance, serving as a foundation for personalized education. While traditional deep learning models achieve high accuracy, they often lack…

Computation and Language · Computer Science 2026-03-25 Runze Li , Kedi Chen , Guwei Feng , Mo Yu , Jun Wang , Wei Zhang

Interest in generative Electrocardiogram-Language Models (ELMs) is growing, as they can produce textual responses conditioned on ECG signals and textual queries. Unlike traditional classifiers that output label probabilities, ELMs are more…

Computation and Language · Computer Science 2025-10-02 Xiaoyu Song , William Han , Tony Chen , Chaojing Duan , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by integrating external knowledge, where the LLM's ability to generate responses based on the combination of a given query and retrieved documents is crucial.…

Computation and Language · Computer Science 2025-08-01 Zhehao Tan , Yihan Jiao , Dan Yang , Lei Liu , Jie Feng , Duolin Sun , Yue Shen , Jian Wang , Peng Wei , Jinjie Gu

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…

Computation and Language · Computer Science 2024-07-09 Bojana Bašaragin , Adela Ljajić , Darija Medvecki , Lorenzo Cassano , Miloš Košprdić , Nikola Milošević

While holding great promise for improving and facilitating healthcare, large language models (LLMs) struggle to produce up-to-date responses on evolving topics due to outdated knowledge or hallucination. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2024-12-23 Gongbo Zhang , Zihan Xu , Qiao Jin , Fangyi Chen , Yilu Fang , Yi Liu , Justin F. Rousseau , Ziyang Xu , Zhiyong Lu , Chunhua Weng , Yifan Peng

Large language models (LLMs) encode knowledge in parametric weights, making it costly to update or extend without retraining. Retrieval-augmented generation (RAG) mitigates this limitation by appending retrieved text to the input, but…

Computation and Language · Computer Science 2026-04-24 Bin Ju , Shenfeng Weng , Danying Zhou , Rongkai Xu , Kunkai Su

Retrieval-augmented generation (RAG) frameworks enable large language models (LLMs) to retrieve relevant information from a knowledge base and incorporate it into the context for generating responses. This mitigates hallucinations and…

Computation and Language · Computer Science 2024-04-09 Pouria Rouzrokh , Shahriar Faghani , Cooper U. Gamble , Moein Shariatnia , Bradley J. Erickson

Retrieval-augmented generation (RAG) is a key means to effectively enhance large language models (LLMs) in many knowledge-based tasks. However, existing RAG methods struggle with knowledge-intensive reasoning tasks, because useful…

Computation and Language · Computer Science 2024-10-28 Zhuoqun Li , Xuanang Chen , Haiyang Yu , Hongyu Lin , Yaojie Lu , Qiaoyu Tang , Fei Huang , Xianpei Han , Le Sun , Yongbin Li

Current medical language models, adapted from large language models (LLMs), typically predict ICD code-based diagnosis from electronic health records (EHRs) because these labels are readily available. However, ICD codes do not capture the…

Computation and Language · Computer Science 2025-12-09 Wenhao Li , Hongkuan Zhang , Hongwei Zhang , Zhengxu Li , Zengjie Dong , Yafan Chen , Niranjan Bidargaddi , Hong Liu

Retrieval-Augmented Generation (RAG) models are designed to incorporate external knowledge, reducing hallucinations caused by insufficient parametric (internal) knowledge. However, even with accurate and relevant retrieved content, RAG…

Computation and Language · Computer Science 2025-01-22 Zhongxiang Sun , Xiaoxue Zang , Kai Zheng , Yang Song , Jun Xu , Xiao Zhang , Weijie Yu , Yang Song , Han Li

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…