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Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho

Large language models (LLMs) have shown superior performance without task-specific fine-tuning. Despite the success, the knowledge stored in the parameters of LLMs could still be incomplete and difficult to update due to the computational…

Computation and Language · Computer Science 2023-10-10 Yile Wang , Peng Li , Maosong Sun , Yang Liu

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

Knowledge Graph Retrieval-Augmented Generation (KG-RAG) extends the RAG paradigm by incorporating structured knowledge from knowledge graphs, enabling Large Language Models (LLMs) to perform more precise and explainable reasoning. While…

Computation and Language · Computer Science 2026-02-04 Jing Ren , Bowen Li , Ziqi Xu , Xikun Zhang , Haytham Fayek , Xiaodong Li

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

The Retrieval-Augmented Language Model (RALM) has shown remarkable performance on knowledge-intensive tasks by incorporating external knowledge during inference, which mitigates the factual hallucinations inherited in large language models…

Computation and Language · Computer Science 2024-12-20 Yuan Xia , Jingbo Zhou , Zhenhui Shi , Jun Chen , Haifeng Huang

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large Language Models (LLMs) have achieved exceptional capabilities in open generation across various domains, yet they encounter difficulties with tasks that require intensive knowledge. To address these challenges, methods for integrating…

Computation and Language · Computer Science 2024-12-17 Fali Wang , Runxue Bao , Suhang Wang , Wenchao Yu , Yanchi Liu , Wei Cheng , Haifeng Chen

Large Language Models (LLMs) are proficient at generating coherent and contextually relevant text but face challenges when addressing knowledge-intensive queries in domain-specific and factual question-answering tasks. Retrieval-augmented…

Information Retrieval · Computer Science 2024-10-08 Garima Agrawal , Tharindu Kumarage , Zeyad Alghamdi , Huan Liu

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

Computation and Language · Computer Science 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Large language models (LLMs) frequently generate confident yet factually incorrect content when used for language generation (a phenomenon often known as hallucination). Retrieval augmented generation (RAG) tries to reduce factual errors by…

Information Retrieval · Computer Science 2026-04-01 Dobrik Georgiev , Kheeran Naidu , Alberto Cattaneo , Federico Monti , Carlo Luschi , Daniel Justus

Safe and trustworthy use of Large Language Models (LLM) in the processing of healthcare documents and scientific papers could substantially help clinicians, scientists and policymakers in overcoming information overload and focusing on the…

An evolving solution to address hallucination and enhance accuracy in large language models (LLMs) is Retrieval-Augmented Generation (RAG), which involves augmenting LLMs with information retrieved from an external knowledge source, such as…

Computation and Language · Computer Science 2024-12-23 Derrick Quinn , Mohammad Nouri , Neel Patel , John Salihu , Alireza Salemi , Sukhan Lee , Hamed Zamani , Mohammad Alian

Large pre-trained language models have been shown to store factual knowledge in their parameters, and achieve state-of-the-art results when fine-tuned on downstream NLP tasks. However, their ability to access and precisely manipulate…

Fine-tuning large language models (LLMs) with high-quality knowledge has been shown to enhance their performance effectively. However, there is a paucity of research on the depth of domain-specific knowledge comprehension by LLMs and the…

Computation and Language · Computer Science 2026-03-19 Haoxuan Yin , Bojian Liu , Chen Tang , Yangfan Wang , Lian Yan , Jingchi Jiang

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

Retrieval-augmented generation (RAG) is a promising approach to address the limitations of fixed knowledge in large language models (LLMs). However, current benchmarks for evaluating RAG systems suffer from two key deficiencies: (1) they…

Computation and Language · Computer Science 2025-01-28 Zehan Qi , Rongwu Xu , Zhijiang Guo , Cunxiang Wang , Hao Zhang , Wei Xu

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Large Language Models~(LLMs) are prone to hallucinations, and Retrieval-Augmented Generation (RAG) helps mitigate this, but at a high computational cost while risking misinformation. Adaptive retrieval aims to retrieve only when necessary,…