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The L1-regularized Gaussian maximum likelihood estimator (MLE) has been shown to have strong statistical guarantees in recovering a sparse inverse covariance matrix, or alternatively the underlying graph structure of a Gaussian Markov…

Machine Learning · Computer Science 2013-06-14 Cho-Jui Hsieh , Matyas A. Sustik , Inderjit S. Dhillon , Pradeep Ravikumar

The application of machine learning models can be significantly impeded by the occurrence of distributional shifts, as the assumption of homogeneity between the population of training and testing samples in machine learning and statistics…

Machine Learning · Statistics 2023-06-06 Wenlu Tang , Zicheng Liu

We develop estimation for potentially high-dimensional additive structural equation models. A key component of our approach is to decouple order search among the variables from feature or edge selection in a directed acyclic graph encoding…

Methodology · Statistics 2014-12-02 Peter Bühlmann , Jonas Peters , Jan Ernest

Posterior sampling for high-dimensional Bayesian inverse problems is a common challenge in real-world applications. Randomized Maximum Likelihood (RML) is an optimization based methodology that gives samples from an approximation to the…

Computation · Statistics 2024-09-05 Valentin Breaz , Richard Wilkinson

Structured latent variables allow incorporating meaningful prior knowledge into deep learning models. However, learning with such variables remains challenging because of their discrete nature. Nowadays, the standard learning approach is to…

Machine Learning · Computer Science 2021-10-29 Kirill Struminsky , Artyom Gadetsky , Denis Rakitin , Danil Karpushkin , Dmitry Vetrov

Robust and efficient optimization methods for variance component estimation using Restricted Maximum Likelihood (REML) models for genetic mapping of quantitative traits are considered. We show that the standard Newton-AI scheme may fail…

Other Quantitative Biology · Quantitative Biology 2007-11-19 Kateryna Mishchenko , Sverker Holmgren , Lars Ronnegard

We propose an analytical solution for approximating the gradient of the Evidence Lower Bound (ELBO) in variational inference problems where the statistical model is a Bayesian network consisting of observations drawn from a mixture of a…

Machine Learning · Computer Science 2025-04-14 Roumen Nikolaev Popov

Maximum Likelihood Estimators (MLE) has many good properties. For example, the asymptotic variance of MLE solution attains equality of the asymptotic Cram{\'e}r-Rao lower bound (efficiency bound), which is the minimum possible variance for…

Machine Learning · Statistics 2019-11-05 Song Liu , Takafumi Kanamori , Wittawat Jitkrittum , Yu Chen

Estimating covariance parameters for multivariate spatial Gaussian random fields is computationally challenging, as the number of parameters grows rapidly with the number of variables, and likelihood evaluation requires operations of order…

Methodology · Statistics 2026-04-10 Francisco Cuevas-Pacheco , Gabriel Riffo , Xavier Emery

Spatial generalized linear mixed models (SGLMMs) are popular and flexible models for non-Gaussian spatial data. They are useful for spatial interpolations as well as for fitting regression models that account for spatial dependence, and are…

Methodology · Statistics 2021-10-26 Yawen Guan , Murali Haran

Causal mediation analysis with random interventions has become an area of significant interest for understanding time-varying effects with longitudinal and survival outcomes. To tackle causal and statistical challenges due to the complex…

Methodology · Statistics 2023-04-12 Zeyi Wang , Lars van der Laan , Maya Petersen , Thomas Gerds , Kajsa Kvist , Mark van der Laan

Marginal maximum likelihood estimation (MMLE) in item response theory (IRT) is highly sensitive to aberrant responses, such as careless answering and random guessing, which can reduce estimation accuracy. To address this issue, this study…

Methodology · Statistics 2025-02-18 Yuki Itaya , Kenichi Hayashi

In this paper we describe a new methodology to calculate analytically the error for a maximum likelihood estimate (MLE) for physical parameters from Gravitational wave signals. All the existing litterature focuses on the usage of the Cramer…

General Relativity and Quantum Cosmology · Physics 2011-08-15 Michele Zanolin , Salvatore Vitale , Nicholas Makris

Models with a large number of latent variables are often used to fully utilize the information in big or complex data. However, they can be difficult to estimate using standard approaches, and variational inference methods are a popular…

Methodology · Statistics 2021-04-20 Rubén Loaiza-Maya , Michael Stanley Smith , David J. Nott , Peter J. Danaher

Datasets in the fields of climate and environment are often very large and irregularly spaced. To model such datasets, the widely used Gaussian process models in spatial statis- tics face tremendous challenges due to the prohibitive…

Methodology · Statistics 2016-05-31 Huang Huang , Ying Sun

Intractable distributions present a common difficulty in inference within the probabilistic knowledge representation framework and variational methods have recently been popular in providing an approximate solution. In this article, we…

Artificial Intelligence · Computer Science 2011-05-30 D. Barber , P. de van Laar

In this paper, we investigate the empirical counterpart of Group Distributionally Robust Optimization (GDRO), which aims to minimize the maximal empirical risk across $m$ distinct groups. We formulate empirical GDRO as a…

Machine Learning · Computer Science 2024-09-23 Dingzhi Yu , Yunuo Cai , Wei Jiang , Lijun Zhang

We propose a framework for computing, optimizing and integrating with respect to a smooth marginal likelihood in statistical models that involve high-dimensional parameters/latent variables and continuous low-dimensional hyperparameters.…

Methodology · Statistics 2026-02-10 Omiros Papaspiliopoulos , Timothée Stumpf-Fétizon , Jonathan Weare

Modern applications of Bayesian inference involve models that are sufficiently complex that the corresponding posterior distributions are intractable and must be approximated. The most common approximation is based on Markov chain Monte…

Machine Learning · Statistics 2019-05-15 Yue Yang , Ryan Martin , Howard Bondell

While Deep Neural Networks (DNNs) achieve remarkable performance, their tendency to produce overconfident predictions. Evidential Deep Learning (EDL) mitigates this by formulating predictions as a Dirichlet distribution over class…

Machine Learning · Computer Science 2026-05-27 Jiawei Tang , Xinyan Du , Hui Liu , Junhui Hou , Yuheng Jia