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Time periodic patterns in a semiconductor superlattice, relevant to microwave generation, are obtained upon numerical integration of a known set of drift-diffusion equations. The associated spatio-temporal transport mechanisms are uncovered…

Materials Science · Physics 2021-10-01 F. Terragni , L. L. Bonilla , J. M. Vega

Foundation models have recently gained significant attention because of their generalizability and adaptability across multiple tasks and data distributions. Although medical foundation models have emerged, solutions for cardiac imaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Sekeun Kim , Pengfei Jin , Sifan Song , Cheng Chen , Yiwei Li , Hui Ren , Xiang Li , Tianming Liu , Quanzheng Li

Accurate spatiotemporal pattern analysis is critical in fields such as urban traffic, meteorology, and public health monitoring. However, existing methods face performance bottlenecks, typically yielding only incremental gains and often…

Machine Learning · Computer Science 2026-05-20 Jing Chen , Shixiang Pan , Yujie Fan , Haocheng Ye , Haitao Xu , Wenqiang Xu

Myocardial motion and deformation are rich descriptors that characterize cardiac function. Image registration, as the most commonly used technique for myocardial motion tracking, is an ill-posed inverse problem which often requires prior…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Chen Qin , Shuo Wang , Chen Chen , Wenjia Bai , Daniel Rueckert

The accurate, reliable and efficient numerical approximation of multi-physics processes in heterogeneous porous media with varying media coefficients that include fluid flow and structure interactions is of fundamental importance in energy,…

Numerical Analysis · Mathematics 2018-01-17 Uwe Köcher

Cardiovascular disease arises from interactions between inherited risk, molecular programmes, and tissue-scale remodelling that are observed clinically through imaging. Health systems now routinely generate large volumes of cardiac MRI, CT…

Quantitative Methods · Quantitative Biology 2026-01-14 Minh H. N. Le , Tuan Vinh , Thanh-Huy Nguyen , Tao Li , Bao Quang Gia Le , Han H. Huynh , Monika Raj , Carl Yang , Min Xu , Nguyen Quoc Khanh Le

Respiratory airflow signals provide critical insight into breathing mechanics, yet conventional analysis methods remain limited in their ability to characterize the internal structure of individual breaths. Traditional approaches treat…

Signal Processing · Electrical Eng. & Systems 2026-04-27 Victoria Ribeiro Rodrigues , Paul W. Davenport , Nicholas J. Napoli

We derive an equation that governs the spatiotemporal dynamics of small amplitude alternans in paced cardiac tissue. We show that a pattern-forming linear instability leads to the spontaneous formation of stationary or traveling waves whose…

Statistical Mechanics · Physics 2009-11-07 Blas Echebarria , Alain Karma

We discuss the spatiotemporal behavior of local density and its relation to dynamical heterogeneity in a highly supercooled liquid by using molecular dynamics simulations of a binary mixture with different particle sizes in two dimensions.…

Soft Condensed Matter · Physics 2015-03-20 Hayato Shiba , Takeshi Kawasaki

The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…

Medical Physics · Physics 2023-08-03 Sebastian Skatulla , Carlo Sansour , Mary Familusi , Jagir Hussan , Ntobeko Ntusi

In silico tissue models enable evaluating quantitative models of magnetic resonance imaging. This includes validating and sensitivity analysis of imaging biomarkers and tissue microstructure parameters. We propose a novel method to generate…

We propose a multi-scale lung model to investigate spatio-temporal distributions of ventilation variables. Lung envelope and large airway geometries are derived from CT scans; smaller airways are generated using a physiologically consistent…

Tissues and Organs · Quantitative Biology 2026-03-31 Jonathan Stéphano , Michaël Brunengo , Riccardo Di Dio , Thomas Laporte , Benjamin Mauroy

Purpose: This study proposes a novel anatomically-driven dynamic modeling framework for coronary arteries using skeletal skinning weights computation, aiming to achieve precise control over vessel deformation while maintaining real-time…

Graphics · Computer Science 2025-03-05 Shuo Wang , Tong Ren , Nan Cheng , Rong Wang , Li Zhang

Microfluidic technology has emerged as a powerful tool for studying complex biological processes with enhanced precision and control. A microfluidic chip was designed to emulate human-like microvascular networks with precise control over…

Biological Physics · Physics 2025-02-18 Shobhit Das , Shilpi Pandey , Oliver Hayden

We develop a technique for the multivariate data analysis of perturbed self-sustained oscillators. The approach is based on the reconstruction of the phase dynamics model from observations and on a subsequent exploration of this model. For…

Medical Physics · Physics 2019-06-03 M. Rosenblum , M. Frühwirth , M. Moser , A. Pikovsky

Quantitative assessment of cardiac left ventricle (LV) morphology is essential to assess cardiac function and improve the diagnosis of different cardiovascular diseases. In current clinical practice, LV quantification depends on the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-25 Sulaiman Vesal , Mingxuan Gu , Andreas Maier , Nishant Ravikumar

In cases of pressure or volume overload, probing cardiac function may be difficult because of the interactions between shape and deformations.In this work, we use the LDDMM framework and parallel transport to estimate and reorient…

Computer Vision and Pattern Recognition · Computer Science 2021-02-18 Nicolas Guigui , Pamela Moceri , Maxime Sermesant , Xavier Pennec

Deep learning enables automatic and robust extraction of cardiac function descriptors from echocardiographic sequences, such as ejection fraction or strain. These descriptors provide fine-grained information that physicians consider, in…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Nathan Painchaud , Jérémie Stym-Popper , Pierre-Yves Courand , Nicolas Thome , Pierre-Marc Jodoin , Nicolas Duchateau , Olivier Bernard

Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…

Medical Physics · Physics 2026-03-05 Nathan Dermul , Hans Dierckx

Large observational clinical datasets become increasingly available for mining associations between various disease traits and administered therapy. These datasets can be considered as representations of the landscape of all possible…