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Coordinating large populations of grid-edge devices requires learning methods that remain fully decentralised in deployment while still respecting three-phase AC distribution-network physics. This paper proposes gradient-based multi-agent…

Machine Learning · Computer Science 2026-04-28 Yihong Zhou , Hongtai Zeng , Thomas Morstyn

The rapid growth of memory and computation requirements of large language models (LLMs) has outpaced the development of hardware, hindering people who lack large-scale high-end GPUs from training or deploying LLMs. However, consumer-level…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-06 Zhenheng Tang , Yuxin Wang , Xin He , Longteng Zhang , Xinglin Pan , Qiang Wang , Rongfei Zeng , Kaiyong Zhao , Shaohuai Shi , Bingsheng He , Xiaowen Chu

The Cellular Potts Model (CPM) is a widely used simulation paradigm for systems of interacting cells that has been used to study scenarios ranging from plant development to morphogenesis, tumour growth and cell migration. Despite their wide…

Tissues and Organs · Quantitative Biology 2023-12-18 Shabaz Sultan , Sapna Devi , Scott N. Mueller , Johannes Textor

Development of computer technology in chemistry, bring many application of chemistry. Not only the application to visualize the structure of molecule but also to molecular dynamics simulation. One of them is Gromacs. Gromacs is an example…

Computational Engineering, Finance, and Science · Computer Science 2009-12-07 A. D. Astuti , A. B. Mutiara

We develop an algorithm suitable for parallel molecular dynamics simulations in $d$ spatial dimensions and describe its implementation in C++. All routines work in arbitrary $d$; the maximum simulated $d$ is limited only by available…

Soft Condensed Matter · Physics 2022-05-18 Robert S. Hoy , Kevin A. Interiano-Alberto

Modern GPU systems are constantly evolving to meet the needs of computing-intensive applications in scientific and machine learning domains. However, there is typically a gap between the hardware capacity and the achievable application…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-02 Gabin Schieffer , Ruimin Shi , Stefano Markidis , Andreas Herten , Jennifer Faj , Ivy Peng

The distributed computing infrastructure (DCI) on the basis of BOINC and EDGeS-bridge technologies for high-performance distributed computing is used for porting the sequential molecular dynamics (MD) application to its parallel version for…

Computational Engineering, Finance, and Science · Computer Science 2014-04-24 Olexander Gatsenko , Lev Bekenev , Evgen Pavlov , Yuri G. Gordienko

A modern graphics processing unit (GPU) is able to perform massively parallel scientific computations at low cost. We extend our implementation of the checkerboard algorithm for the two dimensional Ising model [T. Preis et al., J. Comp.…

Computational Physics · Physics 2010-07-22 Benjamin Block , Peter Virnau , Tobias Preis

The introduction of AI and ML technologies into medical devices has revolutionized healthcare diagnostics and treatments. Medical device manufacturers are keen to maximize the advantages afforded by AI and ML by consolidating multiple…

Software Engineering · Computer Science 2024-02-08 Soham Sinha , Shekhar Dwivedi , Mahdi Azizian

The rapid advancement of deep learning is reshaping the hardware design landscape toward AI tasks, posing fundamental challenges for HPC workloads such as atomistic simulation. Here we present SMC-AI, a general algorithmic framework that…

This article introduces a highly parallel algorithm for molecular dynamics simulations with short-range forces on single node multi- and many-core systems. The algorithm is designed to achieve high parallel speedups for strongly…

Computational Physics · Physics 2013-11-20 R. Meyer

Mass spectrometry (MS) is essential for proteomics and metabolomics but faces impending challenges in efficiently processing the vast volumes of data. This paper introduces SpecPCM, an in-memory computing (IMC) accelerator designed to…

Hardware Architecture · Computer Science 2024-11-18 Keming Fan , Ashkan Moradifirouzabadi , Xiangjin Wu , Zheyu Li , Flavio Ponzina , Anton Persson , Eric Pop , Tajana Rosing , Mingu Kang

Molecular dynamics (MD) simulations provide atomistic insights into the structure, dynamics, and function of biomolecules by generating time-resolved, high-dimensional trajectories. Analyzing such data benefits from estimating the minimal…

Biomolecules · Quantitative Biology 2026-03-02 Irene Cazzaniga , Toni Giorgino

We present an active learning framework for efficiently generating training data for machine-learned interatomic potentials (MLIPs). The method combines local entropy-driven molecular dynamics with global dataset-aware filtering: a…

Materials Science · Physics 2026-05-21 Meiyan Wang , Rishi Rao , Li Zhu

Since its inception in 1995, LAMMPS has grown to be a world-class molecular dynamics code, with thousands of users, over one million lines of code, and multi-scale simulation capabilities. We discuss how LAMMPS has adapted to the modern…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-25 Anders Johansson , Evan Weinberg , Christian R. Trott , Megan J. McCarthy , Stan G. Moore

State of the art domain decomposition algorithms for large-scale boundary value problems (with $M\gg 1$ degrees of freedom) suffer from bounded strong scalability because they involve the synchronisation and communication of workers…

Numerical Analysis · Mathematics 2023-08-21 Francisco Bernal , Jorge Morón-Vidal , Juan A. Acebrón

Machine learning interatomic potentials (MLIPs) have transformed materials discovery by leveraging graph neural networks (GNNs) to predict material properties with near density functional theory (DFT) accuracy. While large-scale pretrained…

Materials Science · Physics 2026-05-29 Rushikesh Pawar , Harshit Rawat , Ayush Kumar , Phani Motamarri

Understanding the dynamic behavior of biomolecules is fundamental to elucidating biological function and facilitating drug discovery. While Molecular Dynamics (MD) simulations provide a rigorous physical basis for studying these dynamics,…

Biomolecules · Quantitative Biology 2026-03-19 Liang Shi , Jiarui Lu , Junqi Liu , Chence Shi , Zhi Yang , Jian Tang

In recent years, Graph Neural Networks (GNNs) have achieved remarkable success in many graph mining tasks. However, scaling them to large graphs is challenging due to the high computational and storage costs of repeated feature propagation…

Machine Learning · Computer Science 2025-04-11 Yuxuan Liang , Wentao Zhang , Zeang Sheng , Ling Yang , Quanqing Xu , Jiawei Jiang , Yunhai Tong , Bin Cui

We present a new deep learning-based machine learning potential (MLP) for molecular dynamics simulations of solid carbon monoxide (CO), capable of accurately describing CO vibrations both in the fundamental state and in highly excited…