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Mitochondrial diseases are currently untreatable due to our limited understanding of their pathology. We study the expression of various mitochondrial proteins in skeletal myofibres (SM) in order to discover processes involved in…

Machine Learning · Computer Science 2022-11-01 Atif Khan , Conor Lawless , Amy E Vincent , Satish Pilla , Sushanth Ramesh , A. Stephen McGough

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Euler's elastica constitute an appealing variational image inpainting model. It minimises an energy that involves the total variation as well as the level line curvature. These components are transparent and make it attractive for shape…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Karl Schrader , Tobias Alt , Joachim Weickert , Michael Ertel

Functional magnetic resonance imaging or functional MRI (fMRI) is a non-invasive way to assess brain activity by detecting changes associated with blood flow. In this work, we propose a full Bayesian procedure to analyze fMRI data for…

Neurodegeneration as measured through magnetic resonance imaging (MRI) is recognized as a potential biomarker for diagnosing Alzheimer's disease (AD), but is generally considered less specific than amyloid or tau based biomarkers. Due to a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Rosemary He , Gabriella Ang , Daniel Tward

Learning energy-based model (EBM) requires MCMC sampling of the learned model as an inner loop of the learning algorithm. However, MCMC sampling of EBMs in high-dimensional data space is generally not mixing, because the energy function,…

Machine Learning · Statistics 2022-03-17 Erik Nijkamp , Ruiqi Gao , Pavel Sountsov , Srinivas Vasudevan , Bo Pang , Song-Chun Zhu , Ying Nian Wu

The diagnosis, prognosis, and treatment of patients with musculoskeletal (MSK) disorders require radiology imaging (using computed tomography, magnetic resonance imaging(MRI), and ultrasound) and their precise analysis by expert…

Image and Video Processing · Electrical Eng. & Systems 2020-03-03 Ismail Irmakci , Syed Muhammad Anwar , Drew A. Torigian , Ulas Bagci

This work proposes $\mu$GUIDE: a general Bayesian framework to estimate posterior distributions of tissue microstructure parameters from any given biophysical model or MRI signal representation, with exemplar demonstration in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Maëliss Jallais , Marco Palombo

Energy-based models (EBMs) are generative models that are usually trained via maximum likelihood estimation. This approach becomes challenging in generic situations where the trained energy is non-convex, due to the need to sample the Gibbs…

Machine Learning · Computer Science 2022-02-16 Carles Domingo-Enrich , Alberto Bietti , Marylou Gabrié , Joan Bruna , Eric Vanden-Eijnden

We propose a novel unsupervised deep-learning-based algorithm for dynamic magnetic resonance imaging (MRI) reconstruction. Dynamic MRI requires rapid data acquisition for the study of moving organs such as the heart. Existing reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Jaejun Yoo , Kyong Hwan Jin , Harshit Gupta , Jerome Yerly , Matthias Stuber , Michael Unser

Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Churan Wang , Fei Gao , Lijun Yan , Siwen Wang , Yizhou Yu , Yizhou Wang

Electron and scanning probe microscopy produce vast amounts of data in the form of images or hyperspectral data, such as EELS or 4D STEM, that contain information on a wide range of structural, physical, and chemical properties of…

Machine Learning · Computer Science 2023-06-09 Arpan Biswas , Maxim Ziatdinov , Sergei V. Kalinin

We present topological derivative and energy based procedures for the imaging of micro and nanostructures using one beam of visible light of a single wavelength. Objects with diameters as small as 10 nm can be located, and their position…

Biological Physics · Physics 2016-10-04 A. Carpio , T. G. Dimiduk , M. L. Rapun , V. Selgas

Deep neural networks can approximate functions on different types of data, from images to graphs, with varied underlying structure. This underlying structure can be viewed as the geometry of the data manifold. By extending recent advances…

Machine Learning · Computer Science 2023-01-03 Saket Tiwari , George Konidaris

Deep learning (DL) models for segmenting various anatomical structures have achieved great success via a static DL model that is trained in a single source domain. Yet, the static DL model is likely to perform poorly in a continually…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Xiaofeng Liu , Helen A. Shih , Fangxu Xing , Emiliano Santarnecchi , Georges El Fakhri , Jonghye Woo

Machine learning (ML) is shaping our exploration of topological matter, whose existence is inherently tied to the geometry of quantum states or energy spectra. In non-Hermitian systems, distinctive spectral geometry can lead to topological…

Single-subject mapping of resting-state brain functional activity to non-imaging phenotypes is a major goal of neuroimaging. The large majority of learning approaches applied today rely either on static representations or on short-term…

Machine Learning · Computer Science 2022-08-09 Ahmed El-Gazzar , Rajat Mani Thomas , Guido Van Wingen

Noninvasive MR-guided focused ultrasound (MRgFUS) treatments are promising alternatives to the surgical removal of malignant tumors. A significant challenge is assessing the viability of treated tissue during and immediately after MRgFUS…

Image and Video Processing · Electrical Eng. & Systems 2020-10-01 Blake E. Zimmerman , Sara Johnson , Henrik Odéen , Jill Shea , Markus D. Foote , Nicole Winkler , Sarang C. Joshi , Allison Payne

Image-based personalized medicine has the potential to transform healthcare, particularly for diseases that exhibit heterogeneous progression such as Multiple Sclerosis (MS). In this work, we introduce the first treatment-aware…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Gian Mario Favero , Ge Ya Luo , Nima Fathi , Justin Szeto , Douglas L. Arnold , Brennan Nichyporuk , Chris Pal , Tal Arbel

What is the shortest path between two data points lying in a high-dimensional space? While the answer is trivial in Euclidean geometry, it becomes significantly more complex when the data lies on a curved manifold -- requiring a Riemannian…

Machine Learning · Computer Science 2025-11-04 Louis Béthune , David Vigouroux , Yilun Du , Rufin VanRullen , Thomas Serre , Victor Boutin
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