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The widespread adoption of electronic health records has created new opportunities for translational clinical research, yet this promise remains constrained by fragmented data across privacy-siloed institutions and substantial heterogeneity…

This work introduces a unified framework for analyzing games in greater depth. In the existing literature, players' strategies are typically assigned scalar values, and equilibrium concepts are used to identify compatible choices. However,…

Computer Science and Game Theory · Computer Science 2026-02-04 Melih İşeri , Erhan Bayraktar

The recent trend towards Personalized Federated Learning (PFL) has garnered significant attention as it allows for the training of models that are tailored to each client while maintaining data privacy. However, current PFL techniques…

Machine Learning · Computer Science 2023-05-03 Yue Wu , Shuaicheng Zhang , Wenchao Yu , Yanchi Liu , Quanquan Gu , Dawei Zhou , Haifeng Chen , Wei Cheng

Within the evolving field of digital intervention, serious games emerge as promising tools for evidence-based interventions. Research indicates that gamified therapy, whether employed independently or in conjunction with online…

Human-Computer Interaction · Computer Science 2024-04-17 Julieana Moon , Naimul Khan

Federated learning offers a privacy-preserving framework for recommendation systems by enabling local data processing; however, data localization introduces substantial obstacles. Traditional federated recommendation approaches treat each…

Machine Learning · Computer Science 2026-03-10 Xudong Wang , Qingbo Hao , Yingyuan Xiao

Strategic coopetition in multi-stakeholder systems requires understanding how cooperation persists through time without binding contracts. This technical report extends computational foundations for strategic coopetition to sequential…

Multiagent Systems · Computer Science 2026-04-03 Vik Pant , Eric Yu

Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. Modern approaches for data generation based on machine…

Machine Learning · Computer Science 2023-01-11 Chao Yan , Yao Yan , Zhiyu Wan , Ziqi Zhang , Larsson Omberg , Justin Guinney , Sean D. Mooney , Bradley A. Malin

In Oncology, trials evaluating drug combinations are becoming more common. While combination therapies bring the potential for greater efficacy, they also create unique challenges for ensuring drug safety. In Phase-I dose escalation trials…

Applications · Statistics 2023-02-23 Lukas A. Widmer , Andrew Bean , David Ohlssen , Sebastian Weber

This article reviews recent advances in applying natural language processing (NLP) to Electronic Health Records (EHRs) for computational phenotyping. NLP-based computational phenotyping has numerous applications including diagnosis…

Computation and Language · Computer Science 2018-06-18 Zexian Zeng , Yu Deng , Xiaoyu Li , Tristan Naumann , Yuan Luo

Preference learning from human feedback has the ability to align generative models with the needs of end-users. Human feedback is costly and time-consuming to obtain, which creates demand for data-efficient query selection methods. This…

Machine Learning · Computer Science 2026-02-18 Guy Schacht , Ziyad Sheebaelhamd , Riccardo De Santi , Mojmír Mutný , Andreas Krause

Identifying genetic interactions for a given microorganism such as yeast is difficult. Quantitative Fitness Analysis (QFA) is a high-throughput experimental and computational methodology for quantifying the fitness of microbial cultures.…

Applications · Statistics 2014-05-29 Jonathan Heydari

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

In this paper, we study decentralized decision-making where agents optimize private objectives under incomplete information and imperfect public monitoring, in a non-cooperative setting. By shaping utilities-embedding shadow prices or…

Computer Science and Game Theory · Computer Science 2025-10-31 David Smith , Jie Dong , Yizhou Yang

We investigate mean-field games (MFG) in which agents can actively control their speed of access to information. Specifically, the agents can dynamically decide to obtain observations with reduced delay by accepting higher observation…

Optimization and Control · Mathematics 2025-06-03 Dirk Becherer , Christoph Reisinger , Jonathan Tam

Standard simulations of the Iterated Prisoners Dilemma (IPD) operate in deterministic, noise-free environments, producing strategies that may be theoretically optimal but fragile when confronted with real-world uncertainty. This paper…

Neural and Evolutionary Computing · Computer Science 2026-01-07 Oguzhan Yildirim

Achieving optimal balance in games is essential to their success, yet reliant on extensive manual work and playtesting. To facilitate this process, the Procedural Content Generation via Reinforcement Learning (PCGRL) framework has recently…

Human-Computer Interaction · Computer Science 2024-09-10 Florian Rupp , Alessandro Puddu , Christian Becker-Asano , Kai Eckert

Promoting healthy lifestyle behaviors remains a major public health concern, particularly due to their crucial role in preventing chronic conditions such as cancer, heart disease, and type 2 diabetes. Mobile health applications present a…

Machine Learning · Computer Science 2024-05-24 Aishwarya Mandyam , Matthew Jörke , William Denton , Barbara E. Engelhardt , Emma Brunskill

We present a personalized and reliable prediction model for healthcare, which can provide individually tailored medical services such as diagnosis, disease treatment, and prevention. Our proposed framework targets at making personalized and…

Machine Learning · Statistics 2019-11-26 Ingyo Chung , Saehoon Kim , Juho Lee , Kwang Joon Kim , Sung Ju Hwang , Eunho Yang

Aligning large language models (LLMs) with human values and safety constraints is challenging, especially when objectives like helpfulness, truthfulness, and avoidance of harm conflict. Reinforcement Learning from Human Feedback (RLHF) has…

Computation and Language · Computer Science 2025-03-31 Xuying Li , Zhuo Li , Yuji Kosuga , Victor Bian

In this paper, we present a unifying framework for analyzing equilibria and designing interventions for large network games sampled from a stochastic network formation process represented by a graphon. We first introduce a new class of…

Computer Science and Game Theory · Computer Science 2020-07-01 Francesca Parise , Asuman Ozdaglar
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