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Large language models (LLMs) are increasingly used for medical consultation and health information support. In this high-stakes setting, safety depends not only on medical knowledge, but also on how models respond when patient inputs are…

Computation and Language · Computer Science 2026-04-01 Yahan Li , Xinyi Jie , Wanjia Ruan , Xubei Zhang , Huaijie Zhu , Yicheng Gao , Chaohao Du , Ruishan Liu

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

Though Large Vision-Language Models (LVLMs) are being actively explored in medicine, their ability to conduct complex real-world telemedicine consultations combining accurate diagnosis with professional dialogue remains underexplored. This…

Human-Computer Interaction · Computer Science 2025-11-12 Ivan Sviridov , Amina Miftakhova , Artemiy Tereshchenko , Galina Zubkova , Pavel Blinov , Andrey Savchenko

As Large Language Models (LLMs) are increasingly deployed as task-oriented agents in enterprise environments, ensuring their strict adherence to complex, domain-specific operational guidelines is critical. While utilizing an LLM-as-a-Judge…

Computation and Language · Computer Science 2026-04-15 Jingbo Yang , Guanyu Yao , Bairu Hou , Xinghan Yang , Nikolai Glushnev , Iwona Bialynicka-Birula , Duo Ding , Shiyu Chang

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Large Language Models (LLMs) are increasingly deployed for knowledge synthesis, yet their capacity for compositional generalization in scientific knowledge remains under-characterized. Existing benchmarks primarily focus on single-turn…

Artificial Intelligence · Computer Science 2026-05-15 Gong Zhiren , Tiantong Wu , Jiaming Zhang , Fuyao Zhang , Che Wang , Yurong Hao , Yikun Hou , Foo Ping , Yilei Zhao , Fei Huang , Chau Yuen , Wei Yang Bryan Lim

The evaluation and improvement of medical large language models (LLMs) are critical for their real-world deployment, particularly in ensuring accuracy, safety, and ethical alignment. Existing frameworks inadequately dissect domain-specific…

Computation and Language · Computer Science 2025-03-11 Luyi Jiang , Jiayuan Chen , Lu Lu , Xinwei Peng , Lihao Liu , Junjun He , Jie Xu

Large language models (LLMs) are entering clinician workflows, yet evaluations rarely measure how clinician reasoning shapes model behavior during clinical interactions. We combined 61 New England Journal of Medicine Case Records with 92…

With the rapid advancement of Large Language Models (LLMs), the safety of LLMs has been a critical concern requiring precise assessment. Current benchmarks primarily concentrate on single-turn dialogues or a single jailbreak attack method…

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

Artificial Intelligence · Computer Science 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

We present MedPI, a high-dimensional benchmark for evaluating large language models (LLMs) in patient-clinician conversations. Unlike single-turn question-answer (QA) benchmarks, MedPI evaluates the medical dialogue across 105 dimensions…

Computation and Language · Computer Science 2026-01-09 Diego Fajardo V. , Oleksii Proniakin , Victoria-Elisabeth Gruber , Razvan Marinescu

While large language models (LLMs) hold transformative potential for medicine, their reasoning robustness and safety in real-world clinical scenarios remain critically underexplored, particularly in dentistry. Here we introduce…

An effective healthcare agent must be able to recall and reason over a patient's longitudinal medical history. However, the absence of datasets with realistic long-term dialogue timelines limits systematic evaluation. Real clinical text is…

Computation and Language · Computer Science 2026-05-20 Hebin Hu , Renke Dai , Ah-Hwee Tan , Yilin Kang

Large Language Models (LLMs) are increasingly deployed in socially complex, interaction-driven tasks, yet their ability to mirror human behavior in emotionally and strategically complex contexts remains underexplored. This study assesses…

Computation and Language · Computer Science 2025-09-23 Deuksin Kwon , Kaleen Shrestha , Bin Han , Elena Hayoung Lee , Gale Lucas

Evaluating Large Language Models (LLMs) for mental health support is challenging due to the emotionally and cognitively complex nature of therapeutic dialogue. Existing benchmarks are limited in scale, reliability, often relying on…

Speech large language models (SpeechLLMs) have extended human-machine interactions from the text modality to the dynamic speech domain. Spoken dialogues convey diverse information, including semantic concepts, acoustic variations,…

Computation and Language · Computer Science 2026-01-14 Heyang Liu , Yuhao Wang , Ziyang Cheng , Hongcheng Liu , Yiqi Li , Yixuan Hou , Ronghua Wu , Qunshan Gu , Yanfeng Wang , Yu Wang

Users typically engage with LLMs interactively, yet most existing benchmarks evaluate them in a static, single-turn format, posing reliability concerns in interactive scenarios. We identify a key obstacle towards reliability: LLMs are…

Computation and Language · Computer Science 2024-11-08 Shuyue Stella Li , Vidhisha Balachandran , Shangbin Feng , Jonathan S. Ilgen , Emma Pierson , Pang Wei Koh , Yulia Tsvetkov

Mental disorders are highly prevalent worldwide, but the shortage of psychiatrists and the inherent subjectivity of interview-based diagnosis create substantial barriers to timely and consistent mental-health assessment. Progress in…

Multiagent Systems · Computer Science 2026-02-12 Shihao Xu , Tiancheng Zhou , Jiatong Ma , Yanli Ding , Yiming Yan , Ming Xiao , Guoyi Li , Haiyang Geng , Yunyun Han , Jianhua Chen , Yafeng Deng

Clinical decision-making in emergency medicine demands rapid, accurate diagnoses under uncertainty. Despite benchmark progress, evidence for LLMs as interactive aids in live physician workflows remains sparse. MedSyn lets physicians…

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