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Biomedical question answering often requires decisions from retrieved literature whose relevance, quality, and support for candidate answers are uneven. Most retrieval-augmented large language model (LLM) methods feed this literature to the…

Computation and Language · Computer Science 2026-05-19 Chang Zong , Hao Ning , Siliang Tang , Jie Huang , Jian Wan

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10…

Computation and Language · Computer Science 2025-07-08 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Medical problem-solving demands expert knowledge and intricate reasoning. Recent studies of large language models (LLMs) attempt to ease this complexity by introducing external knowledge verification through retrieval-augmented generation…

Computation and Language · Computer Science 2026-01-19 Yue Huang , Yanyuan Chen , Dexuan Xu , Chenzhuo Zhao , Weihua Yue , Yu Huang

As large language models (LLMs) become increasingly integrated into clinical decision-making, ensuring transparent and trustworthy reasoning is essential. However, existing evaluation strategies of LLMs' medical reasoning capability either…

Large language models (LLMs) are increasingly deployed in clinical decision support, yet subtle demographic cues can influence their reasoning. Prior work has documented disparities in outputs across patient groups, but little is known…

Computation and Language · Computer Science 2025-10-16 Rajarshi Ghosh , Abhay Gupta , Hudson McBride , Anurag Vaidya , Faisal Mahmood

Due to their architecture and vast pre-training data, large language models (LLMs) demonstrate strong text classification performance. However, LLM output - here, the category assigned to a text - depends heavily on the wording of the…

Computation and Language · Computer Science 2025-12-04 Kylie L. Anglin , Stephanie Milan , Brittney Hernandez , Claudia Ventura

Clinical decision-making requires synthesizing heterogeneous evidence, including patient histories, clinical guidelines, and trajectories of comparable cases. While large language models (LLMs) offer strong reasoning capabilities, they…

Artificial Intelligence · Computer Science 2026-03-03 Shuheng Chen , Namratha Patil , Haonan Pan , Angel Hsing-Chi Hwang , Yao Du , Ruishan Liu , Jieyu Zhao

Electronic Health Records (EHRs) often lack explicit links between medications and diagnoses, making clinical decision-making and research more difficult. Even when links exist, diagnosis lists may be incomplete, especially during early…

Computation and Language · Computer Science 2025-03-31 Dina Albassam , Adam Cross , Chengxiang Zhai

It is desirable to coarsely classify short scientific texts, such as grant or publication abstracts, for strategic insight or research portfolio management. These texts efficiently transmit dense information to experts possessing a rich…

Artificial Intelligence · Computer Science 2024-07-09 Harsh Sakhrani , Naseela Pervez , Anirudh Ravi Kumar , Fred Morstatter , Alexandra Graddy Reed , Andrea Belz

Abstracts derived from biomedical literature possess distinct domain-specific characteristics, including specialised writing styles and biomedical terminologies, which necessitate a deep understanding of the related literature. As a result,…

Computation and Language · Computer Science 2023-10-25 Chen Tang , Shun Wang , Tomas Goldsack , Chenghua Lin

Timely and accurate situational reports are essential for humanitarian decision-making, yet current workflows remain largely manual, resource intensive, and inconsistent. We present a fully automated framework that uses large language…

Computation and Language · Computer Science 2025-12-23 Ivan Decostanzi , Yelena Mejova , Kyriaki Kalimeri

The Micropublications semantic model for scientific claims, evidence, argumentation and annotation in biomedical publications, is a metadata model of scientific argumentation, designed to support several key requirements for exchange and…

Digital Libraries · Computer Science 2014-02-04 Tim Clark , Paolo N. Ciccarese , Carole A. Goble

Plain language summaries (PLSs) are essential for facilitating effective communication between clinicians and patients by making complex medical information easier for laypeople to understand and act upon. Large language models (LLMs) have…

Computation and Language · Computer Science 2025-05-16 Yue Guo , Jae Ho Sohn , Gondy Leroy , Trevor Cohen

Extracting structured information from text, such as key-value pairs that could augment tabular data, is quite useful in many enterprise use cases. Although large language models (LLMs) have enabled numerous automated pipelines for…

Computation and Language · Computer Science 2025-07-30 Satyananda Kashyap , Sola Shirai , Nandana Mihindukulasooriya , Horst Samulowitz

This study investigates the automation of meta-analysis in scientific documents using large language models (LLMs). Meta-analysis is a robust statistical method that synthesizes the findings of multiple studies support articles to provide a…

Computation and Language · Computer Science 2024-11-19 Jawad Ibn Ahad , Rafeed Mohammad Sultan , Abraham Kaikobad , Fuad Rahman , Mohammad Ruhul Amin , Nabeel Mohammed , Shafin Rahman

The surge in scientific submissions has placed increasing strain on the traditional peer-review process, prompting the exploration of large language models (LLMs) for automated review generation. While LLMs demonstrate competence in…

Computation and Language · Computer Science 2025-09-25 Ruochi Li , Haoxuan Zhang , Edward Gehringer , Ting Xiao , Junhua Ding , Haihua Chen

HealthBranches is a novel benchmark dataset for medical Question-Answering (Q&A), specifically designed to evaluate complex reasoning in Large Language Models (LLMs). This dataset is generated through a semi-automated pipeline that…

Computation and Language · Computer Science 2025-08-12 Cristian Cosentino , Annamaria Defilippo , Marco Dossena , Christopher Irwin , Sara Joubbi , Pietro Liò

Abstract. Automatically generating scientific literature surveys is a valuable task that can significantly enhance research efficiency. However, the diverse and complex nature of information within a literature survey poses substantial…

Computation and Language · Computer Science 2024-08-16 Yuxuan Lai , Yupeng Wu , Yidan Wang , Wenpeng Hu , Chen Zheng

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins
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