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The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…

Artificial Intelligence · Computer Science 2026-04-28 Zhiqi Lv , Duofan Tu , Jun Li , Mingyue Zhao , Heqin Zhu , Wenliang Li , Shaohua Kevin Zhou

We present a novel framework that bridges the gap between the interpretability of decision trees and the advanced reasoning capabilities of large language models (LLMs) to predict startup success. Our approach leverages chain-of-thought…

Artificial Intelligence · Computer Science 2025-04-17 Jack Preuveneers , Joseph Ternasky , Fuat Alican , Yigit Ihlamur

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Vision-Language Models (VLMs) frequently "hallucinate" - generate plausible yet factually incorrect statements - posing a critical barrier to their trustworthy deployment. In this work, we propose a new paradigm for diagnosing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Lexiang Xiong , Qi Li , Jingwen Ye , Xinchao Wang

An extensive library of symptom inventories has been developed over time to measure clinical symptoms, but this variety has led to several long standing issues. Most notably, results drawn from different settings and studies are not…

Computation and Language · Computer Science 2023-09-12 Eamonn Kennedy , Shashank Vadlamani , Hannah M Lindsey , Kelly S Peterson , Kristen Dams OConnor , Kenton Murray , Ronak Agarwal , Houshang H Amiri , Raeda K Andersen , Talin Babikian , David A Baron , Erin D Bigler , Karen Caeyenberghs , Lisa Delano-Wood , Seth G Disner , Ekaterina Dobryakova , Blessen C Eapen , Rachel M Edelstein , Carrie Esopenko , Helen M Genova , Elbert Geuze , Naomi J Goodrich-Hunsaker , Jordan Grafman , Asta K Haberg , Cooper B Hodges , Kristen R Hoskinson , Elizabeth S Hovenden , Andrei Irimia , Neda Jahanshad , Ruchira M Jha , Finian Keleher , Kimbra Kenney , Inga K Koerte , Spencer W Liebel , Abigail Livny , Marianne Lovstad , Sarah L Martindale , Jeffrey E Max , Andrew R Mayer , Timothy B Meier , Deleene S Menefee , Abdalla Z Mohamed , Stefania Mondello , Martin M Monti , Rajendra A Morey , Virginia Newcombe , Mary R Newsome , Alexander Olsen , Nicholas J Pastorek , Mary Jo Pugh , Adeel Razi , Jacob E Resch , Jared A Rowland , Kelly Russell , Nicholas P Ryan , Randall S Scheibel , Adam T Schmidt , Gershon Spitz , Jaclyn A Stephens , Assaf Tal , Leah D Talbert , Maria Carmela Tartaglia , Brian A Taylor , Sophia I Thomopoulos , Maya Troyanskaya , Eve M Valera , Harm Jan van der Horn , John D Van Horn , Ragini Verma , Benjamin SC Wade , Willian SC Walker , Ashley L Ware , J Kent Werner , Keith Owen Yeates , Ross D Zafonte , Michael M Zeineh , Brandon Zielinski , Paul M Thompson , Frank G Hillary , David F Tate , Elisabeth A Wilde , Emily L Dennis

The diagnosis of most mental disorders, including psychiatric evaluations, primarily depends on dialogues between psychiatrists and patients. This subjective process can lead to variability in diagnoses across clinicians and patients,…

Artificial Intelligence · Computer Science 2025-10-30 Eranga Bandara , Ross Gore , Atmaram Yarlagadda , Anita H. Clayton , Preston Samuel , Christopher K. Rhea , Sachin Shetty

Foundation models, including vision language models, are increasingly used in automated driving to interpret scenes, recommend actions, and generate natural language explanations. However, existing evaluation methods primarily assess…

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine learning and deep learning models have achieved notable…

Machine Learning · Computer Science 2025-01-09 Qiuhao Lu , Rui Li , Elham Sagheb , Andrew Wen , Jinlian Wang , Liwei Wang , Jungwei W. Fan , Hongfang Liu

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

The development of intelligent agents, particularly those powered by language models (LMs), has shown a critical role in various environments that require intelligent and autonomous decision-making. Environments are not passive testing…

Artificial Intelligence · Computer Science 2025-10-21 Antonin Sulc , Thorsten Hellert

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Accurate and interpretable image-based diagnosis remains a fundamental challenge in medical AI, particularly under domain shifts and rare-class conditions. Deep learning models often struggle with real-world distribution changes, exhibit…

Machine Learning · Computer Science 2025-12-13 Midhat Urooj , Ayan Banerjee , Farhat Shaikh , Kuntal Thakur , Sandeep Gupta

Neurosymbolic (NeSy) frameworks combine neural representations and learning with symbolic representations and reasoning. Combining the reasoning capacities, explainability, and interpretability of symbolic processing with the flexibility…

Artificial Intelligence · Computer Science 2025-09-10 Sania Sinha , Tanawan Premsri , Danial Kamali , Parisa Kordjamshidi

Chain-of-Thought reasoning is widely used to improve the interpretability of multimodal large language models (MLLMs), yet the faithfulness of the generated reasoning traces remains unclear. Prior work has mainly focused on perceptual…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Weijiang Lv , Yaoxuan Feng , Xiaobo Xia , Jiayu Wang , Yan Jing , Wenchao Chen , Bo Chen

Recent studies of the applications of conversational AI tools, such as chatbots powered by large language models, to complex real-world knowledge work have shown limitations related to reasoning and multi-step problem solving. Specifically,…

Artificial Intelligence · Computer Science 2024-03-06 Nova Spivack , Sam Douglas , Michelle Crames , Tim Connors

Deep neural networks are increasingly employed in high-stakes medical applications, despite their tendency for shortcut learning in the presence of spurious correlations, which can have potentially fatal consequences in practice. Whereas a…

Artificial Intelligence · Computer Science 2025-07-30 Frederik Pahde , Thomas Wiegand , Sebastian Lapuschkin , Wojciech Samek

Autonomous AI is no longer a hard-to-reach concept, it enables the agents to move beyond executing tasks to independently addressing complex problems, adapting to change while handling the uncertainty of the environment. However, what makes…

Neurons and Cognition · Quantitative Biology 2025-05-12 Zinan Liu , Haoran Li , Jingyi Lu , Gaoyuan Ma , Xu Hong , Giovanni Iacca , Arvind Kumar , Shaojun Tang , Lin Wang

Rule-based systems remain central in safety-critical domains but often struggle with scalability, brittleness, and goal misspecification. These limitations can lead to reward hacking and failures in formal verification, as AI systems tend…

Logic in Computer Science · Computer Science 2026-05-12 Zainab Rehan , Christian Medeiros Adriano , Sona Ghahremani , Holger Giese

In this paper, we offer a guide for researchers on evaluating reasoning in language models, building the case that reasoning should be assessed through evidence of adaptive, multi-step search rather than final-answer accuracy alone. Under…

Artificial Intelligence · Computer Science 2026-05-05 Munachiso Samuel Nwadike , Zangir Iklassov , Kareem Ali , Rifo Genadi , Kentaro Inui
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